Cell death in disease: from 2010 onwards

The p53 family: guardians of maternal reproduction

(2011) Arnold J. Levine et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Functional phosphoproteomic analysis reveals cold-shock domain protein A to be a Bcr-Abl effector-regulating proliferation and transformation in chronic myeloid leukemia

(2011) D Sears et al.   Cell Death & Disease

Rapid and efficient cancer cell killing mediated by high-affinity death receptor homotrimerizing TRAIL variants

(2011) C R Reis et al.   Cell Death & Disease

Downregulation of microRNA-383 is associated with male infertility and promotes testicular embryonal carcinoma cell proliferation by targeting IRF1

(2011) J Lian et al.   Cell Death & Disease

Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101 and miR-98

(2011) N M Alajez et al.   Cell Death & Disease

The CD14+/lowCD16+ monocyte subset is more susceptible to spontaneous and oxidant-induced apoptosis than the CD14+CD16− subset

(2011) C Zhao et al.   Cell Death & Disease

Necrostatin-1 ameliorates symptoms in R6/2 transgenic mouse model of Huntington's disease

(2011) S Zhu et al.   Cell Death & Disease

p53 stabilization: the importance of nuclear import

(2010) J-C Marine   CELL DEATH AND DIFFERENTIATION

Integrated analysis of microRNA and mRNA expression profiles in physiological myelopoiesis: role of hsa-mir-299-5p in CD34+ progenitor cells commitment

(2010) E Tenedini et al.   Cell Death & Disease

Calreticulin exposure on malignant blasts predicts a cellular anticancer immune response in patients with acute myeloid leukemia

(2010) M Wemeau et al.   Cell Death & Disease

Synergistic induction of cell death in liver tumor cells by TRAIL and chemotherapeutic drugs via the BH3-only proteins Bim and Bid

(2010) S Schneider-Jakob et al.   Cell Death & Disease

A potential role for NEDD1 and the centrosome in senescence of mouse embryonic fibroblasts

(2010) J A Manning et al.   Cell Death & Disease

Phosphorylation of Puma modulates its apoptotic function by regulating protein stability

(2010) M Fricker et al.   Cell Death & Disease

Pegylated IFN-α sensitizes melanoma cells to chemotherapy and causes premature senescence in endothelial cells by IRF-1-mediated signaling

(2010) M Upreti et al.   Cell Death & Disease

Expression of coxsackie and adenovirus receptor distinguishes transitional cancer states in therapy-induced cellular senescence

(2010) P C Wu et al.   Cell Death & Disease

Apoptosis of human melanoma cells induced by inhibition of B-RAFV600E involves preferential splicing of bimS

(2010) C C Jiang et al.   Cell Death & Disease

Potent antitumoral activity of TRAIL through generation of tumor-targeted single-chain fusion proteins

(2010) B Schneider et al.   Cell Death & Disease

Excessive HDAC activation is critical for neurodegeneration in the rd1 mouse

(2010) J Sancho-Pelluz et al.   Cell Death & Disease

Drosophila happyhour modulates JNK-dependent apoptosis

(2010) D Lam et al.   Cell Death & Disease

Magnesium induces neuronal apoptosis by suppressing excitability

(2010) W H Dribben et al.   Cell Death & Disease

Proton pump inhibition induces autophagy as a survival mechanism following oxidative stress in human melanoma cells

(2010) M L Marino et al.   Cell Death & Disease

Characterization of a caspase-3-substrate kinome using an N- and C-terminally tagged protein kinase library produced by a cell-free system

(2010) D Tadokoro et al.   Cell Death & Disease

Protein kinase Cθ is required for cardiomyocyte survival and cardiac remodeling

(2010) R Paoletti et al.   Cell Death & Disease

Mitochondrial translocation of oxidized cofilin induces caspase-independent necrotic-like programmed cell death of T cells

(2010) G H Wabnitz et al.   Cell Death & Disease

Role of the JNK/c-Jun/AP-1 signaling pathway in galectin-1-induced T-cell death

(2010) B Brandt et al.   Cell Death & Disease

BH3-only proteins BIM and PUMA in the regulation of survival and neuronal differentiation of newly generated cells in the adult mouse hippocampus

(2010) E C Bunk et al.   Cell Death & Disease

c-Abl phosphorylation of ΔNp63α is critical for cell viability

(2010) M Yuan et al.   Cell Death & Disease

Activation of mTOR coincides with autophagy during ligation-induced atrophy in the rat submandibular gland

(2010) N Silver et al.   Cell Death & Disease

c-Abl downregulates the slow phase of double-strand break repair

(2010) V Meltser et al.   Cell Death & Disease

Loss of protein kinase C delta alters mammary gland development and apoptosis

(2010) B L Allen-Petersen et al.   Cell Death & Disease

Baifuzi reduces transient ischemic brain damage through an interaction with the STREX domain of BKCa channels

(2010) S Chi et al.   Cell Death & Disease

Palmitoylation of human FasL modulates its cell death-inducing function

(2010) F Guardiola-Serrano et al.   Cell Death & Disease

Impact of the DNA methyltransferases expression on the methylation status of apoptosis-associated genes in glioblastoma multiforme

(2010) E Hervouet et al.   Cell Death & Disease

Linking calorie restriction to longevity through sirtuins and autophagy: any role for TOR

(2010) M V Blagosklonny   Cell Death & Disease

Prions and neuronal death

(2010) G Di Guardo et al.   Cell Death & Disease

Spatio-temporal radiation biology: new insights and biomedical perspectives

(2010) S Lacombe et al.   Cell Death & Disease

Cell Death and Disease: a new journal for a central area of pathophysiology

(2010) G Kroemer et al.   Cell Death & Disease

Mutant Huntingtin induces activation of the Bcl-2/adenovirus E1B 19-kDa interacting protein (BNip3)

(2010) J Sassone et al.   Cell Death & Disease

CXCL12 inhibits expression of the NMDA receptor's NR2B subunit through a histone deacetylase-dependent pathway contributing to neuronal survival

(2010) J Nicolai et al.   Cell Death & Disease

The novel estrogen-induced gene EIG121 regulates autophagy and promotes cell survival under stress

(2010) L Deng et al.   Cell Death & Disease

Bcl-2 antagonists and cancer: from the clinic, back to the bench

(2010) M Degli Esposti   Cell Death & Disease

The anti-apoptotic function of human αA-crystallin is directly related to its chaperone activity

(2010) N Pasupuleti et al.   Cell Death & Disease

FK506-binding protein 51 is a possible novel tumoral marker

(2010) S Romano et al.   Cell Death & Disease

Survivin withdrawal by nuclear export failure as a physiological switch to commit cells to apoptosis

(2010) K-S Chan et al.   Cell Death & Disease

MEK–ERK-dependent multiple caspase activation by mitochondrial proapoptotic Bcl-2 family proteins is essential for heavy ion irradiation-induced glioma cell death

(2010) A Tomiyama et al.   Cell Death & Disease

An otoprotective role for the apoptosis inhibitor protein survivin

(2010) S K Knauer et al.   Cell Death & Disease

Partial dysferlin reconstitution by adult murine mesoangioblasts is sufficient for full functional recovery in a murine model of dysferlinopathy

(2010) J Díaz-Manera et al.   Cell Death & Disease

Novel p63 target genes involved in paracrine signaling and keratinocyte differentiation

(2010) C E Barton et al.   Cell Death & Disease

Resistance to caspase-8 and -9 fragments in a malignant pleural mesothelioma cell line with acquired cisplatin-resistance

(2010) V Janson et al.   Cell Death & Disease

Enhanced cartilage regeneration in MIA/CD-RAP deficient mice

(2010) R Schmid et al.   Cell Death & Disease

Increase in the density of resting microglia precedes neuritic plaque formation and microglial activation in a transgenic model of Alzheimer's disease

(2010) J J Rodríguez et al.   Cell Death & Disease

p73 deficiency results in impaired self renewal and premature neuronal differentiation of mouse neural progenitors independently of p53

(2010) L Gonzalez-Cano et al.   Cell Death & Disease

Bcl-2-regulated cell death signalling in the prevention of autoimmunity

(2010) D Tischner et al.   Cell Death & Disease

Endoplasmic reticulum stress inhibition protects steatotic and non-steatotic livers in partial hepatectomy under ischemia–reperfusion

(2010) I Ben Mosbah et al.   Cell Death & Disease

Alterations of brain and cerebellar proteomes linked to Aβ and tau pathology in a female triple-transgenic murine model of Alzheimer's disease

(2010) D Ciavardelli et al.   Cell Death & Disease

Negative regulation of UCP2 by TGFβ signaling characterizes low and intermediate-grade primary breast cancer

(2010) A Sayeed et al.   Cell Death & Disease

Differential effects of the phosphatidylinositol 4-kinases, PI4KIIα and PI4KIIIβ, on Akt activation and apoptosis

(2010) K M E Chu et al.   Cell Death & Disease

Inhibition of TXNIP expression in vivo blocks early pathologies of diabetic retinopathy

(2010) L Perrone et al.   Cell Death & Disease

Lithium reduces apoptosis and autophagy after neonatal hypoxia–ischemia

(2010) Q Li et al.   Cell Death & Disease

Cytotoxicity of apigenin on leukemia cell lines: implications for prevention and therapy

(2010) R R Ruela-de-Sousa et al.   Cell Death & Disease

Apigenin-induced apoptosis of leukemia cells is mediated by a bimodal and differentially regulated residue-specific phosphorylation of heat-shock protein–27

(2010) M E Gonzalez-Mejia et al.   Cell Death & Disease

MicroRNA-21 dysregulates the expression of MEF2C in neurons in monkey and human SIV/HIV neurological disease

(2010) S V Yelamanchili et al.   Cell Death & Disease

Histone deacetylase 1 and 2 differentially regulate apoptosis by opposing effects on extracellular signal-regulated kinase 1/2

(2010) W-W Lei et al.   Cell Death & Disease

Low concentrations of nitric oxide delay the differentiation of embryonic stem cells and promote their survival

(2010) J R Tejedo et al.   Cell Death & Disease

p53-mediated delayed NF-κB activity enhances etoposide-induced cell death in medulloblastoma

(2010) D Meley et al.   Cell Death & Disease

Cytotoxicity of amyloidogenic immunoglobulin light chains in cell culture

(2010) L A Sikkink et al.   Cell Death & Disease

Autism spectrum disorder is related to endoplasmic reticulum stress induced by mutations in the synaptic cell adhesion molecule, CADM1

(2010) E Fujita et al.   Cell Death & Disease

Cathepsin B-like and cell death in the unicellular human pathogen Leishmania

(2010) A K El-Fadili et al.   Cell Death & Disease

The C-terminus of p63 contains multiple regulatory elements with different functions

(2010) W E Straub et al.   Cell Death & Disease

Giant unilamellar vesicles (GUVs) as a new tool for analysis of caspase-8/Bid-FL complex binding to cardiolipin and its functional activity

(2010) O Jalmar et al.   Cell Death & Disease

Carnitine reduces the lipoperoxidative damage of the membrane and apoptosis after induction of cell stress in experimental glaucoma

(2010) N Calandrella et al.   Cell Death & Disease

Structural and functional neuroprotection in glaucoma: role of galantamine-mediated activation of muscarinic acetylcholine receptors

(2010) M Almasieh et al.   Cell Death & Disease

Familial amyloid precursor protein mutants cause caspase-6-dependent but amyloid β-peptide-independent neuronal degeneration in primary human neuron cultures.

(2010) S N Sivananthan et al.   Cell Death & Disease

TGF-β induces TIAF1 self-aggregation via type II receptor-independent signaling that leads to generation of amyloid β plaques in Alzheimer's disease

(2010) M-H Lee et al.   Cell Death & Disease

c-Flip overexpression affects satellite cell proliferation and promotes skeletal muscle aging

(2010) C Giampietri et al.   Cell Death & Disease

The acetylation of RelA in Lys310 dictates the NF-κB-dependent response in post-ischemic injury

(2010) A Lanzillotta et al.   Cell Death & Disease

Intracellular Ca2+ release through ryanodine receptors contributes to AMPA receptor-mediated mitochondrial dysfunction and ER stress in oligodendrocytes

(2010) A Ruiz et al.   Cell Death & Disease

Orai1 contributes to the establishment of an apoptosis-resistant phenotype in prostate cancer cells

(2010) M Flourakis et al.   Cell Death & Disease

Differential neuroprotective effects of 14-3-3 proteins in models of Parkinson's disease

(2010) T A Yacoubian et al.   Cell Death & Disease

Apoptosis-inducing factor deficiency decreases the proliferation rate and protects the subventricular zone against ionizing radiation

(2010) K Osato et al.   Cell Death & Disease

Tropheryma whipplei, the Whipple's disease bacillus, induces macrophage apoptosis through the extrinsic pathway

(2010) L Gorvel et al.   Cell Death & Disease

IGF1 activates cell cycle arrest following irradiation by reducing binding of ΔNp63 to the p21 promoter

(2010) G C Mitchell et al.   Cell Death & Disease

Protection of rat pancreatic islet function and viability by coculture with rat bone marrow-derived mesenchymal stem cells

(2010) E Karaoz et al.   Cell Death & Disease

Downregulation of miR-205 and miR-31 confers resistance to chemotherapy-induced apoptosis in prostate cancer cells

(2010) N Bhatnagar et al.   Cell Death & Disease

XIAP impairs Smac release from the mitochondria during apoptosis

(2010) L Flanagan et al.   Cell Death & Disease

Extraribosomal functions associated with the C terminus of the 37/67 kDa laminin receptor are required for maintaining cell viability

(2010) J Scheiman et al.   Cell Death & Disease

A programmed cell death pathway in the malaria parasite Plasmodium falciparum has general features of mammalian apoptosis but is mediated by clan CA cysteine proteases

(2010) J-H Ch'ng et al.   Cell Death & Disease

Caspase cleavage of the Golgi stacking factor GRASP65 is required for Fas/CD95-mediated apoptosis

(2010) J P X Cheng et al.   Cell Death & Disease

Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy

(2010) E Morselli et al.   Cell Death & Disease

CLIMP-63 is a gentamicin-binding protein that is involved in drug-induced cytotoxicity

(2010) T Karasawa et al.   Cell Death & Disease

Vital function of PRELI and essential requirement of its LEA motif

(2010) M R McKeller et al.   Cell Death & Disease

Pro-apoptotic Bax is the major and Bak an auxiliary effector in cytokine deprivation-induced mast cell apoptosis

(2010) M Karlberg et al.   Cell Death & Disease

JNK phosphorylates Yes-associated protein (YAP) to regulate apoptosis

(2010) V Tomlinson et al.   Cell Death & Disease

Human embryonic stem cell neural differentiation and enhanced cell survival promoted by hypoxic preconditioning

(2010) K R Francis et al.   Cell Death & Disease

Prenatal alcohol exposure triggers ceramide-induced apoptosis in neural crest-derived tissues concurrent with defective cranial development

(2010) G Wang et al.   Cell Death & Disease

Loss of p53 results in protracted electrographic seizures and development of an aggravated epileptic phenotype following status epilepticus

(2010) T Engel et al.   Cell Death & Disease

A survey of the anti-apoptotic Bcl-2 subfamily expression in cancer types provides a platform to predict the efficacy of Bcl-2 antagonists in cancer therapy

(2010) W J Placzek et al.   Cell Death & Disease

Dietary zinc supplementation of 3xTg-AD mice increases BDNF levels and prevents cognitive deficits as well as mitochondrial dysfunction

(2010) C Corona et al.   Cell Death & Disease

Mechanisms of HIV-associated lymphocyte apoptosis: 2010

(2010) N W Cummins et al.   Cell Death & Disease

Long-term (trophic) purinergic signalling: purinoceptors control cell proliferation, differentiation and death

(2010) G Burnstock et al.   Cell Death & Disease

An automated fluorescence videomicroscopy assay for the detection of mitotic catastrophe

(2010) S Rello-Varona et al.   Cell Death & Disease

Glucocorticoids induce long-lasting effects in neural stem cells resulting in senescence-related alterations

(2010) R Bose et al.   Cell Death & Disease

GX15-070 (obatoclax) overcomes glucocorticoid resistance in acute lymphoblastic leukemia through induction of apoptosis and autophagy

(2010) N Heidari et al.   Cell Death & Disease

Obatoclax induces Atg7-dependent autophagy independent of beclin-1 and BAX/BAK

(2010) F McCoy et al.   Cell Death & Disease

Exploring ultrashort high-energy electron-induced damage in human carcinoma cells

(2010) O Rigaud et al.   Cell Death & Disease

Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria

(2010) E Wirawan et al.   Cell Death & Disease

Inhibition of NF-κB activation sensitizes U937 cells to 3′-azido-3′-deoxythymidine induced apoptosis

(2010) C Matteucci et al.   Cell Death & Disease

Calpain activation through galectin-3 inhibition sensitizes prostate cancer cells to cisplatin treatment

(2010) Y Wang et al.   Cell Death & Disease

Imaging multiple phases of neurodegeneration: a novel approach to assessing cell death in vivo

(2010) M F Cordeiro et al.   Cell Death & Disease

The ubiquitin proteasome system and its involvement in cell death pathways

(2009) F Bernassola et al.   CELL DEATH AND DIFFERENTIATION

Regulation of death receptor signaling by the ubiquitin system

(2009) I E Wertz et al.   CELL DEATH AND DIFFERENTIATION

Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs

(2009) J Silke et al.   CELL DEATH AND DIFFERENTIATION

Dual roles of Drosophila p53 in cell death and cell differentiation

(2009) Y Fan et al.   CELL DEATH AND DIFFERENTIATION

TNF-like weak inducer of apoptosis inhibits proinflammatory TNF receptor-1 signaling

(2009) A Wicovsky et al.   CELL DEATH AND DIFFERENTIATION

Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features

(2009) T Vanden Berghe et al.   CELL DEATH AND DIFFERENTIATION

Stress-mediated nuclear stabilization of p53 is regulated by ubiquitination and importin-α3 binding

(2009) N D Marchenko et al.   CELL DEATH AND DIFFERENTIATION

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

(2009) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity

(2009) Richard Tomasini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The HECT Family of E3 Ubiquitin Ligases: Multiple Players in Cancer Development

(2008) Francesca Bernassola et al.   CANCER CELL

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION

TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

(2008) R. Tomasini et al.   GENES & DEVELOPMENT

The impact of p53 and p73 on aneuploidy and cancer

(2008) Richard Tomasini et al.   TRENDS IN CELL BIOLOGY