Familial amyloid precursor protein mutants cause caspase-6-dependent but amyloid β-peptide-independent neuronal degeneration in primary human neuron cultures.

Caspase-6 Activation in Familial Alzheimer Disease Brains Carrying Amyloid Precursor Protein or Presenilin I or Presenilin II Mutations

(2009) Steffen Albrecht et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

(2009) Anatoly Nikolaev et al.   NATURE

Self-activation of Caspase-6 in vitro and in vivo: Caspase-6 activation does not induce cell death in HEK293T cells

(2008) Guy Klaiman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Amyloid precursor protein-induced axonopathies are independent of amyloid-β peptides

(2008) Gorazd B. Stokin et al.   HUMAN MOLECULAR GENETICS

Targets of Caspase-6 Activity in Human Neurons and Alzheimer Disease

(2008) Guy Klaiman et al.   MOLECULAR & CELLULAR PROTEOMICS

Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses

(2008) Lars Bertram et al.   NATURE REVIEWS NEUROSCIENCE

Overexpression of wild-type human APP in mice causes cognitive deficits and pathological features unrelated to Aβ levels

(2008) Ana-María Simón et al.   NEUROBIOLOGY OF DISEASE

Linking Aβ and Tau in Late-Onset Alzheimer's Disease: A Dual Pathway Hypothesis

(2008) Scott A. Small et al.   NEURON