Microglial diversity by responses and responders

The subpopulation of microglia sensitive to neurotransmitters/neurohormones is modulated by stimulation with LPS, interferon-γ, and IL-4

(2014) Maria Pannell et al.   GLIA

Morphometric characterization of microglial phenotypes in human cerebral cortex

(2014) Susana G Torres-Platas et al.   Journal of Neuroinflammation

Single-cell technologies for monitoring immune systems

(2014) Pratip K Chattopadhyay et al.   NATURE IMMUNOLOGY

Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior

(2014) Yang Zhan et al.   NATURE NEUROSCIENCE

Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

(2013) Christopher N. Parkhurst et al.   CELL

Proteins in Microglial Activation - Inputs and Outputs by Subsets

(2013) Uwe-Karsten Hanisch   CURRENT PROTEIN & PEPTIDE SCIENCE

Microglial Phenotype and Adaptation

(2013) B. J. L. Eggen et al.   Journal of Neuroimmune Pharmacology

Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells

(2013) Alex K. Shalek et al.   NATURE

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

Tissue-resident macrophages

(2013) Luke C Davies et al.   NATURE IMMUNOLOGY

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways

(2013) Katrin Kierdorf et al.   NATURE NEUROSCIENCE

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

The microglial sensome revealed by direct RNA sequencing

(2013) Suzanne E Hickman et al.   NATURE NEUROSCIENCE

Spinal but not cortical microglia acquire an atypical phenotype with high VEGF, galectin-3 and osteopontin, and blunted inflammatory responses in ALS rats

(2013) Maria Nikodemova et al.   NEUROBIOLOGY OF DISEASE

Microglia: New Roles for the Synaptic Stripper

(2013) Helmut Kettenmann et al.   NEURON

Distinct activation profiles in microglia of different ages: A systematic study in isolated embryonic to aged microglial cultures

(2013) A.Y. Lai et al.   NEUROSCIENCE

Functional diversity of microglia – how heterogeneous are they to begin with?

(2013) Uwe-Karsten Hanisch   Frontiers in Cellular Neuroscience

Toll-like receptor activation reveals developmental reorganization and unmasks responder subsets of microglia

(2012) Jörg Scheffel et al.   GLIA

Development and homeostasis of “resident” myeloid cells: The case of the microglia

(2012) Elisa Gomez Perdiguero et al.   GLIA

Regulation of microglia development and homeostasis

(2012) Melanie Greter et al.   GLIA

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

(2012) Simon Yona et al.   IMMUNITY

Complement receptor-3 negatively regulates the phagocytosis of degenerated myelin through tyrosine kinase Syk and cofilin

(2012) Smadar Hadas et al.   Journal of Neuroinflammation

Wild-type microglia arrest pathology in a mouse model of Rett syndrome

(2012) Noël C. Derecki et al.   NATURE

Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

(2012) Emmanuel L Gautier et al.   NATURE IMMUNOLOGY

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

Neonatal rat microglia derived from different brain regions have distinct activation responses

(2012) Aaron Y. Lai et al.   Neuron Glia Biology

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

(2012) C. Schulz et al.   SCIENCE

Age related changes in microglial phenotype vary between CNS regions: Grey versus white matter differences

(2011) Adam D. Hart et al.   BRAIN BEHAVIOR AND IMMUNITY

Transmitter- and hormone-activated Ca2+ responses in adult microglia/brain macrophages in situ recorded after viral transduction of a recombinant Ca2+ sensor

(2011) Stefanie Seifert et al.   CELL CALCIUM

Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis

(2011) D. Fitzner et al.   JOURNAL OF CELL SCIENCE

The Fractalkine Receptor but Not CCR2 Is Present on Microglia from Embryonic Development throughout Adulthood

(2011) M. Mizutani et al.   JOURNAL OF IMMUNOLOGY

Myelin down-regulates myelin phagocytosis by microglia and macrophages through interactions between CD47 on myelin and SIRPα (signal regulatory protein-α) on phagocytes

(2011) Miri Gitik et al.   Journal of Neuroinflammation

The Role of Microglia in the Healthy Brain

(2011) M.-E. Tremblay et al.   JOURNAL OF NEUROSCIENCE

Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk

(2011) Xingguang Liu et al.   NATURE IMMUNOLOGY

Heterogeneity of CNS myeloid cells and their roles in neurodegeneration

(2011) Marco Prinz et al.   NATURE NEUROSCIENCE

Physiology of Microglia

(2011) Helmut Kettenmann et al.   PHYSIOLOGICAL REVIEWS

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

CD14 and TRIF govern distinct responsiveness and responses in mouse microglial TLR4 challenges by structural variants of LPS

(2010) Tommy Regen et al.   BRAIN BEHAVIOR AND IMMUNITY

Hematopoietic Origin of Pathological Grooming in Hoxb8 Mutant Mice

(2010) Shau-Kwaun Chen et al.   CELL

Microglia promote colonization of brain tissue by breast cancer cells in a Wnt-dependent way

(2010) Tobias Pukrop et al.   GLIA

The myeloid cells of the central nervous system parenchyma

(2010) Richard M. Ransohoff et al.   NATURE

Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine

(2010) M. T. Heneka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Changing Face of Microglia

(2010) M. B. Graeber   SCIENCE

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Compartmentalization from the outside: the extracellular matrix and functional microdomains in the brain

(2010) Alexander Dityatev et al.   TRENDS IN NEUROSCIENCES

Heterogeneity in astrocyte morphology and physiology

(2009) Vitali Matyash et al.   BRAIN RESEARCH REVIEWS

Toll-Like Receptor Stimulation Enhances Phagocytosis and Intracellular Killing of Nonencapsulated and Encapsulated Streptococcus pneumoniae by Murine Microglia

(2009) S. Ribes et al.   INFECTION AND IMMUNITY

Marked induction of inducible nitric oxide synthase and tumor necrosis factor-α in rat CD40+ microglia by comparison to CD40− microglia

(2009) Kohichi Kawahara et al.   JOURNAL OF NEUROIMMUNOLOGY

Microglia Protect Neurons against Ischemia by Synthesis of Tumor Necrosis Factor

(2009) K. L. Lambertsen et al.   JOURNAL OF NEUROSCIENCE

Resting Microglia Directly Monitor the Functional State of Synapses In Vivo and Determine the Fate of Ischemic Terminals

(2009) H. Wake et al.   JOURNAL OF NEUROSCIENCE

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

Subventricular zone microglia possess a unique capacity for massivein vitroexpansion

(2008) Gregory P. Marshall et al.   GLIA

Region-specific expression of immunoregulatory proteins on microglia in the healthy CNS

(2008) Alexander H. de Haas et al.   GLIA

Long-term accumulation of microglia with proneurogenic phenotype concomitant with persistent neurogenesis in adult subventricular zone after stroke

(2008) Pär Thored et al.   GLIA

Toll-Like Receptor Prestimulation Increases Phagocytosis of Escherichia coli DH5  and Escherichia coli K1 Strains by Murine Microglial Cells

(2008) S. Ribes et al.   INFECTION AND IMMUNITY

Interleukin-1beta and tumor necrosis factor-alpha are expressed by different subsets of microglia and macrophages after ischemic stroke in mice

(2008) Bettina H Clausen et al.   Journal of Neuroinflammation