Bifunctional iminophosphorane catalysed enantioselective sulfa-Michael addition of alkyl thiols to alkenyl benzimidazoles

Enantioselective Formal [3+2] Cycloaddition of Epoxides with Imines under Brønsted Base Catalysis: Synthesis of 1,3-Oxazolidines with Quaternary Stereogenic Center

(2018) Azusa Kondoh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalyst-Enabled Site-Divergent Stereoselective Michael Reactions: Overriding Intrinsic Reactivity of Enynyl Carbonyl Acceptors

(2018) Daisuke Uraguchi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Allenedicarboxylate as a Stereochemically Labile Electrophile for Chiral Organic Base-catalyzed Stereoselective Michael Addition

(2018) Daisuke Uraguchi et al.   CHEMISTRY LETTERS

Asymmetric Organocatalytic Sulfa-Michael Addition to Enone Diesters

(2018) Jennifer L. Fulton et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalyst-Directed Guidance of Sulfur-Substituted Enediolates to Stereoselective Carbon–Carbon Bond Formation with Aldehydes

(2018) Daisuke Uraguchi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective sulfa-Michael addition reaction of methyl thioglycolate to chalcones derivatives with sterically encumbered quinine squaramide organocatalyst

(2018) Deniz Hasılcıoğulları et al.   TETRAHEDRON LETTERS

Asymmetric Net Cycloaddition for Access to Diverse Substituted 1,5-Benzothiazepines

(2017) Yukihiro Fukata et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalytic Enantioselective Synthesis of 3,4-Unsubstituted Thiochromenes through Sulfa-Michael/Julia–Kocienski Olefination Cascade Reaction

(2017) Amit Kumar Simlandy et al.   JOURNAL OF ORGANIC CHEMISTRY

Mechanism and Origins of Stereoselectivity in the Cinchona Thiourea- and Squaramide-Catalyzed Asymmetric Michael Addition of Nitroalkanes to Enones

(2017) Matthew N. Grayson   JOURNAL OF ORGANIC CHEMISTRY

Cinchona Alkaloid-Squaramide Catalyzed Sulfa-Michael Addition Reaction: Mode of Bifunctional Activation and Origin of Stereoinduction

(2017) Jinlong Guo et al.   JOURNAL OF ORGANIC CHEMISTRY

Total Synthesis of (−)-Himalensine A

(2017) Heyao Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cu-Catalyzed Enantioselective Boron Addition to N-Heteroaryl-Substituted Alkenes

(2017) Lu Wen et al.   ORGANIC LETTERS

Enantio- and Diastereoselective Organocatalytic Conjugate Additions of Nitroalkanes to Enone Diesters

(2017) Matthew A. Horwitz et al.   ORGANIC LETTERS

Recent Advances in Enantioselective Brønsted Base Organocatalytic Reactions

(2017) Choon-Hong Tan et al.   SYNLETT

Enantioselective bifunctional iminophosphorane catalyzed sulfa-Michael addition of alkyl thiols to unactivated β-substituted-α,β-unsaturated esters

(2017) Jinchao Yang et al.   Chemical Science

Highly enantioselective catalytic synthesis of chiral pyridines

(2017) Ravindra P. Jumde et al.   Nature Communications

Complete diastereodivergence in asymmetric 1,6-addition reactions enabled by minimal modification of a chiral catalyst

(2017) Daisuke Uraguchi et al.   Nature Communications

Construction of Vicinal Quaternary Stereogenic Centers by Enantioselective Direct Mannich-Type Reaction Using a Chiral Bis(guanidino)iminophosphorane Catalyst

(2016) Tadahiro Takeda et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Functionalized Benzimidazole Scaffolds: Privileged Heterocycle for Drug Design in Therapeutic Medicine

(2016) Olayinka O. Ajani et al.   ARCHIV DER PHARMAZIE

Asymmetric Brønsted Base Catalyzed and Directed [3+2] Cycloaddition of 2-Acyl Cycloheptatrienes with Azomethine Ylides

(2016) Vibeke H. Lauridsen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Synthesis of N−H-Free 1,5-Benzothiazepines

(2016) Guojin Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cinchona Alkaloid-Catalyzed Asymmetric Conjugate Additions: The Bifunctional Brønsted Acid–Hydrogen Bonding Model

(2016) Matthew N. Grayson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cinchona Urea-Catalyzed Asymmetric Sulfa-Michael Reactions: The Brønsted Acid−Hydrogen Bonding Model

(2016) Matthew N. Grayson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic asymmetric addition of Grignard reagents to alkenyl-substituted aromatic N-heterocycles

(2016) R. P. Jumde et al.   SCIENCE

Asymmetric Sulfa-Michael Addition of α,β-Unsaturated Esters/Amides Using a Chiral N-Heterocyclic Carbene as a Noncovalent Organocatalyst

(2016) Jiean Chen et al.   SYNLETT

Asymmetric cycloaddition reactions catalyzed by bifunctional thiourea and squaramide organocatalysts: recent advances

(2016) Felix E. Held et al.   Catalysis Science & Technology

Enantioselective Addition of a 2-Alkoxycarbonyl-1,3-dithiane to Imines Catalyzed by a Bis(guanidino)iminophosphorane Organosuperbase

(2015) Azusa Kondoh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

HighlyE-Selective and Enantioselective Michael Addition to Electron-Deficient Internal Alkynes Under Chiral Iminophosphorane Catalysis

(2015) Daisuke Uraguchi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Aza Michael-Type Addition to Alkenyl Benzimidazoles Catalyzed by a Chiral Phosphoric Acid

(2015) Ya-Yi Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Iminophosphoranes-An Emerging Class of Superbase Organocatalysts

(2015) Henryk Krawczyk et al.   CHEMISTRY-A EUROPEAN JOURNAL

Modularly Evolved 2-AminoDMAP/Squaramides as Highly Active Bifunctional Organocatalysts in Michael Addition

(2015) Murat Işık et al.   JOURNAL OF ORGANIC CHEMISTRY

Higher-Order Cyclopropenimine Superbases: Direct Neutral Brønsted Base Catalyzed Michael Reactions with α-Aryl Esters

(2015) Eric D. Nacsa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bifunctional Iminophosphorane Catalyzed Enantioselective Sulfa-Michael Addition to Unactivated α-Substituted Acrylate Esters

(2015) Alistair J. M. Farley et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Enantioselective Direct Additions of Aldehydes to 4-Vinylpyridines and Electron-Deficient Vinylarenes and Their Synthetic Applications

(2015) Sinan Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Organocatalytic Reductive Coupling Reactions between Benzylidene Pyruvates and Aldehydes

(2015) Matthew A. Horwitz et al.   ORGANIC LETTERS

Design of Highly Stable Iminophosphoranes as Recyclable Organocatalysts: Application to Asymmetric Chlorinations of Oxindoles

(2015) Xing Gao et al.   ORGANIC LETTERS

α-Aroylidineketene dithioacetal chemistry: CuI catalyzed synthesis of 2-styryl benzimidazoles enroute to regioselective hydrothiolation

(2015) Pandi Dhanalakshmi et al.   TETRAHEDRON

Enantioselective reductive multicomponent coupling reactions between isatins and aldehydes

(2015) Matthew A. Horwitz et al.   Chemical Science

Structure–activity relationship studies of cyclopropenimines as enantioselective Brønsted base catalysts

(2015) Jeffrey S. Bandar et al.   Chemical Science

Organocatalytic Enantioselective Sulfur-Michael Addition of Thioacetic Acid to Arylmethylidenemalonates

(2014) Renchao Wang et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Enantioselective Addition of Thioacids to Trisubstituted Nitroalkenes

(2014) James P. Phelan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Comprehensive Review in Current Developments of Benzimidazole-Based Medicinal Chemistry

(2014) Rangappa S. Keri et al.   Chemical Biology & Drug Design

Organocatalytic Carbon–Sulfur Bond-Forming Reactions

(2014) Pankaj Chauhan et al.   CHEMICAL REVIEWS

Benzimidazole: An emerging scaffold for analgesic and anti-inflammatory agents

(2014) Monika Gaba et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Asymmetric Sulfa-Michael Addition to α-Substituted Vinyl Ketones Catalyzed by Chiral Primary Amine

(2014) Niankai Fu et al.   ORGANIC LETTERS

Creation through Immobilization: A New Family of High Performance Heterogeneous Bifunctional Iminophosphorane (BIMP) Superbase Organocatalysts

(2014) Anna M. Goldys et al.   ORGANIC LETTERS

Rh/Pd Catalysis with Chiral and Achiral Ligands: Domino Synthesis of Aza-Dihydrodibenzoxepines

(2013) Adam A. Friedman et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

C═N-Containing Azaarenes as Activating Groups in Enantioselective Catalysis

(2013) Daniel Best et al.   JOURNAL OF ORGANIC CHEMISTRY

Cyclopropenimine-Catalyzed Enantioselective Mannich Reactions of tert-Butyl Glycinates with N-Boc-Imines

(2013) Jeffrey S. Bandar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bifunctional Iminophosphorane Organocatalysts for Enantioselective Synthesis: Application to the Ketimine Nitro-Mannich Reaction

(2013) Marta G. Núñez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Asymmetric Sulfa-Michael Addition of Thiols to α,β-Unsaturated Hexafluoroisopropyl Esters: Expeditious Access to (R)-Thiazesim

(2013) Xin Fang et al.   ORGANIC LETTERS

Organic Superbases: The Concept at a Glance

(2013) Tsutomu Ishikawa et al.   SYNLETT

Organocatalytic enantioselective transient enolate protonation in conjugate addition of thioacetic acid to α-substituted N-acryloyloxazolidinones

(2013) Rajshekhar A. Unhale et al.   TETRAHEDRON LETTERS

Catalytic Asymmetric Conjugate Addition of Thiols to α,β-Unsaturated Thioamides: Expeditious Access to Enantioenriched 1,5-Benzothiazepines

(2012) Takanori Ogawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The therapeutic journey of benzimidazoles: A review

(2012) Yogita Bansal et al.   BIOORGANIC & MEDICINAL CHEMISTRY

A novel C-5′ substituted cinchona alkaloid-derived catalyst promotes additions of alkyl thiols to nitroolefins with excellent enantioselectivity

(2012) Carole Palacio et al.   CHEMICAL COMMUNICATIONS

Chiral-Sc catalyzed asymmetric Michael addition/protonation of thiols with enones in water

(2012) Taku Kitanosono et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective Organocatalytic Thiol Addition to α,β-Unsaturated α-Amino Acid Derivatives

(2012) Henk Hiemstra et al.   SYNLETT

Conjugate Additions to Vinyl-Substituted Aromatic N-Heterocycles

(2012) Douglas Klumpp   SYNLETT

Chiral ionic Brønsted acid–achiral Brønsted base synergistic catalysis for asymmetric sulfa-Michael addition to nitroolefins

(2012) Daisuke Uraguchi et al.   Chemical Science

Mechanistic considerations of guanidine-catalyzed reactions

(2011) Xiao Fu et al.   CHEMICAL COMMUNICATIONS

Sc(III)-Catalyzed Enantioselective Addition of Thiols to α,β-Unsaturated Ketones in Neutral Water

(2011) Simona Bonollo et al.   ORGANIC LETTERS

Enantioselective rhodium-catalyzed arylation of electron-deficient alkenylarenes

(2011) Aakarsh Saxena et al.   Chemical Science

Highly Enantioselective Conjugate Addition of Thioglycolate to Chalcones Catalyzed by Lanthanum: Low Catalyst Loading and Remarkable Chiral Amplification

(2010) Yonghai Hui et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Guanidine Chemistry

(2010) Tsutomu Ishikawa   CHEMICAL & PHARMACEUTICAL BULLETIN

Enantioselective Rhodium-Catalyzed Addition of Arylboronic Acids to Alkenylheteroarenes

(2010) Graham Pattison et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aromatic Heterocycles as Activating Groups for Asymmetric Conjugate Addition Reactions. Enantioselective Copper-Catalyzed Reduction of 2-Alkenylheteroarenes

(2009) Leszek Rupnicki et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric catalysis with bifunctional cinchona alkaloid-based urea and thiourea organocatalysts

(2008) Stephen J. Connon   CHEMICAL COMMUNICATIONS

Asymmetric organocatalysis by chiral Brønsted bases: implications and applications

(2008) Claudio Palomo et al.   CHEMICAL SOCIETY REVIEWS

Hydrogen-Bond-Mediated Asymmetric Catalysis

(2008) Xinhong Yu et al.   Chemistry-An Asian Journal

Chiral Guanidine Catalyzed Enantioselective Reactions

(2008) Dasheng Leow et al.   Chemistry-An Asian Journal