Construction of Vicinal Quaternary Stereogenic Centers by Enantioselective Direct Mannich-Type Reaction Using a Chiral Bis(guanidino)iminophosphorane Catalyst

Enantioselective Addition of a 2-Alkoxycarbonyl-1,3-dithiane to Imines Catalyzed by a Bis(guanidino)iminophosphorane Organosuperbase

(2015) Azusa Kondoh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereoselective Organocatalytic Synthesis of Oxindoles with Adjacent Tetrasubstituted Stereocenters

(2015) Oliver D. Engl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Construction of Vicinal Tetrasubstituted Stereocenters with a C–F Bond through a Catalytic Enantioselective Detrifluoroacetylative Mannich Reaction

(2015) Xihong Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalytic Asymmetric Construction of Vicinal Tetrasubstituted Stereocenters by the Mannich Reaction of Linear α-Substituted Monothiomalonates with Isatin N-Boc Ketimines

(2015) Teng Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Recent Advances in Organocatalytic Cascade Reactions toward the Formation of Quaternary Stereocenters

(2015) Tecla Gasperi et al.   SYNTHESIS-STUTTGART

Managing the retro-pathway in direct catalytic asymmetric aldol reactions of thioamides

(2015) Youmei Bao et al.   Chemical Science

Palladium-Catalyzed Asymmetric Decarboxylative Cycloaddition of Vinylethylene Carbonates with Michael Acceptors: Construction of Vicinal Quaternary Stereocenters

(2014) Ajmal Khan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective Nazarov Cyclization: Construction of Vicinal All-Carbon-Atom Quaternary Stereocenters

(2014) Anais Jolit et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

[2+2] Photocycloaddition of 3-Alkenyloxy-2-cycloalkenones: Enantioselective Lewis Acid Catalysis and Ring Expansion

(2014) Richard Brimioulle et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Construction of Vicinal Tetrasubstituted Stereocenters by the Mannich Reaction of Silyl Ketene Imines with Isatin-Derived Ketimines

(2014) Jiannan Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Bulky Aryl Group-substituted Chiral Bis(guanidino)iminophosphoranes as Uncharged Chiral Organosuperbase Catalysts

(2014) Tadahiro Takeda et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

Phosphine-catalyzed asymmetric [4+1] annulation of activated α,β-unsaturated ketones with Morita–Baylis–Hillman carbonates: enantioselective synthesis of spirooxindoles containing two adjacent quaternary stereocenters

(2014) Fang-Le Hu et al.   CHEMICAL COMMUNICATIONS

All-Carbon Quaternary Stereogenic Centers in Acyclic Systems through the Creation of Several C–C Bonds per Chemical Step

(2014) Ilan Marek et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly enantioselective synthesis of bisoxindoles with two vicinal quaternary stereocenters via Lewis base mediated addition of oxindoles to isatin-derived ketimines

(2014) Zhongkai Tang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Bifunctional N-Heterocyclic Carbene-Catalyzed Highly Enantioselective Synthesis of Spirocyclic Oxindolo-β-lactams

(2014) Han-Ming Zhang et al.   ORGANIC LETTERS

An Organocatalytic Addition of Nitromethane to Activated Ketimines

(2014) Yu-Hui Wang et al.   Asian Journal of Organic Chemistry

CinchonaAlkaloid-Derived Thiourea-Catalyzed Diastereo- and Enantioselective [3+2] Cycloaddition Reaction of Isocyanoacetates to Isatins: A Facile Access to Optically Active Spirooxindole Oxazolines

(2013) Mei-Xin Zhao et al.   ADVANCED SYNTHESIS & CATALYSIS

Palladium-Catalyzed Asymmetric Construction of Vicinal All-Carbon Quaternary Stereocenters and its Application to the Synthesis of Cyclotryptamine Alkaloids

(2013) Barry M. Trost et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective N-Heterocyclic Carbene Catalyzed Aza-Benzoin Reaction of Enals with Activated Ketimines

(2013) Li-Hui Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

One-Pot Tandem Approach to Spirocyclic Oxindoles Featuring Adjacent Spiro-Stereocenters

(2013) Yun-Lin Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

P-chirogenic organocatalysts: application to the aza-Morita–Baylis–Hillman (aza-MBH) reaction of ketimines

(2013) Shinobu Takizawa et al.   CHEMICAL COMMUNICATIONS

Asymmetric Synthesis of Chiral Pyrrolizine-Based Triheterocycles by Organocatalytic Cascade Aza-Michael-Aldol Reactions

(2013) Hyo-Jun Lee et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Synthesis of Congested Spiro-cyclopentaneoxindoles via an Organocatalytic Cascade Reaction

(2013) Artur Noole et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Substitution at the Tetrasubstituted Chiral Carbon: Catalytic Ring-Opening Alkylation of Racemic 2,2-Disubstituted Aziridines with 3-Substituted Oxindoles

(2013) Kohsuke Ohmatsu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development of a Chiral Bis(guanidino)iminophosphorane as an Uncharged Organosuperbase for the Enantioselective Amination of Ketones

(2013) Tadahiro Takeda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Stereoselective Olefin Cyclopropanation of Diazooxindoles Catalyzed by a C2-Symmetric Spiroketal Bisphosphine/Au(I) Complex

(2013) Zhong-Yan Cao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Construction of Vicinal All-Carbon Quaternary Stereocenters by Catalytic Asymmetric Alkylation Reaction of 3-Bromooxindoles with 3-Substituted Indoles: Total Synthesis of (+)-Perophoramidine

(2013) Hailong Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ligand-enabled multiple absolute stereocontrol in metal-catalysed cycloaddition for construction of contiguous all-carbon quaternary stereocentres

(2013) Kohsuke Ohmatsu et al.   Nature Chemistry

Organocatalyzed Formal [2 + 2] Cycloaddition of Ketimines with Allenoates: Facile Access to Azetidines with a Chiral Tetrasubstituted Carbon Stereogenic Center

(2013) Shinobu Takizawa et al.   ORGANIC LETTERS

A Novel Method for Synthesizing N-Alkoxycarbonyl Aryl α-Imino Esters and Their Applications in Enantioselective Transformations

(2012) Yu Qian et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric assembly of 2-oxindole and α-angelica lactone units to construct vicinal quaternary chiral centers

(2012) Xin Huang et al.   CHEMICAL COMMUNICATIONS

Highly Enantio- and Diastereoselective Generation of Two Quaternary Centers in Spirocyclopropanation of Oxindole Derivatives.

(2012) Artur Noole et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of N-Alkoxycarbonyl Ketimines Derived from Isatins and Their Application in Enantioselective Synthesis of 3-Aminooxindoles

(2012) Wenjin Yan et al.   ORGANIC LETTERS

Stereodivergent Direct Catalytic Asymmetric Mannich-Type Reactions of α-Isothiocyanato Ester with Ketimines

(2011) Gang Lu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective synthesis of all-carbon quaternary stereogenic centers in acyclic systems

(2011) Jaya Prakash Das et al.   CHEMICAL COMMUNICATIONS

Oxazaborolidinium Ion-Catalyzed Cyclopropanation of α-Substituted Acroleins: Enantioselective Synthesis of Cyclopropanes Bearing Two Chiral Quaternary Centers

(2011) Lizhu Gao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exercising Regiocontrol in Palladium-Catalyzed Asymmetric Prenylations and Geranylation: Unifying Strategy toward Flustramines A and B

(2011) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Direct Asymmetric Aldol Reactions of 3-Isothiocyanato Oxindoles to Ketones: Stereocontrolled Synthesis of Spirooxindoles Bearing Highly Congested Contiguous Tetrasubstituted Stereocenters

(2011) Wen-Bing Chen et al.   ORGANIC LETTERS

Enantioselective concomitant creation of vicinal quaternary stereogenic centers via cyclization of alkynols triggered addition of azlactones

(2011) Zhi-Yong Han et al.   TETRAHEDRON LETTERS

Catalytic Enantioselective Claisen Rearrangements of O-Allyl β-Ketoesters

(2010) Christopher Uyeda et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal-catalyzed asymmetric conjugate addition reaction: formation of quaternary stereocenters

(2010) Christine Hawner et al.   CHEMICAL COMMUNICATIONS

Construction of Two Vicinal Quaternary Carbons by Asymmetric Allylic Alkylation: Total Synthesis of Hyperolactone C and (−)-Biyouyanagin A

(2009) Chao Du et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Crown Conformation of Rh2(S-PTTL)4: Enantioselective Cyclopropanation with α-Alkyl-α-diazoesters

(2009) Andrew DeAngelis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Construction of Contiguous Tetrasubstituted Chiral Carbon Stereocenters via Direct Catalytic Asymmetric Aldol Reaction of α-Isothiocyanato Esters with Ketones

(2009) Tatsuhiko Yoshino et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoselective Synthesis of Spirooxindoles by Palladium-Catalyzed Decarboxylative Cyclization of γ-Methylidene-δ-valerolactones with Isatins

(2009) Ryo Shintani et al.   ORGANIC LETTERS

Enantioselective Synthesis of β-Trifluoromethyl-β-lactones via NHC-Catalyzed Ketene−Ketone Cycloaddition Reactions

(2009) Xiao-Na Wang et al.   ORGANIC LETTERS