An overview of nanotoxicity and nanomedicine research: principles, progress and implications for cancer therapy

Engineering Poly(ethylene glycol) Particles for Improved Biodistribution

(2015) Jiwei Cui et al.   ACS Nano

The “Sweet” Side of the Protein Corona: Effects of Glycosylation on Nanoparticle–Cell Interactions

(2015) Sha Wan et al.   ACS Nano

Stealth filaments: Polymer chain length and conformation affect the in vivo fate of PEGylated potato virus X

(2015) Karin L. Lee et al.   Acta Biomaterialia

Peroxidase Enzymes Regulate Collagen Extracellular Matrix Biosynthesis

(2015) Mark O. DeNichilo et al.   AMERICAN JOURNAL OF PATHOLOGY

Systematic in vitro nanotoxicity study on anodic alumina nanotubes with engineered aspect ratio: Understanding nanotoxicity by a nanomaterial model

(2015) Ye Wang et al.   BIOMATERIALS

(Intra)Cellular Stability of Inorganic Nanoparticles: Effects on Cytotoxicity, Particle Functionality, and Biomedical Applications

(2015) Stefaan J. Soenen et al.   CHEMICAL REVIEWS

Genotoxicity of metal oxide nanomaterials: review of recent data and discussion of possible mechanisms

(2015) Nazanin Golbamaki et al.   Nanoscale

Principles in the design of ligand-targeted cancer therapeutics and imaging agents

(2015) Madduri Srinivasarao et al.   NATURE REVIEWS DRUG DISCOVERY

Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans

(2015) A. Folick et al.   SCIENCE

Nanoparticle-Mediated Dual Delivery of an Antioxidant and a Peptide against the L-Type Ca2+ Channel Enables Simultaneous Reduction of Cardiac Ischemia-Reperfusion Injury

(2014) Naviin Hardy et al.   ACS Nano

Tuning Cell Autophagy by Diversifying Carbon Nanotube Surface Chemistry

(2014) Ling Wu et al.   ACS Nano

Endoplasmic Reticulum Stress Induced by Zinc Oxide Nanoparticles Is an Earlier Biomarker for Nanotoxicological Evaluation

(2014) Rui Chen et al.   ACS Nano

Porous Silicon Nanodiscs for Targeted Drug Delivery

(2014) Hashim Alhmoud et al.   ADVANCED FUNCTIONAL MATERIALS

Rapid Coating of Surfaces with Functionalized Nanoparticles for Regulation of Cell Behavior

(2014) Rui Tang et al.   ADVANCED MATERIALS

The chemotherapeutic potential of PEG-b-PLGA copolymer micelles that combine chloroquine as autophagy inhibitor and docetaxel as an anti-cancer drug

(2014) Xudong Zhang et al.   BIOMATERIALS

Structurally engineered anodic alumina nanotubes as nano-carriers for delivery of anticancer therapeutics

(2014) Ye Wang et al.   BIOMATERIALS

Cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Nanomaterials for Theranostics: Recent Advances and Future Challenges

(2014) Eun-Kyung Lim et al.   CHEMICAL REVIEWS

Exploiting Intrinsic Nanoparticle Toxicity: The Pros and Cons of Nanoparticle-Induced Autophagy in Biomedical Research

(2014) Karen Peynshaert et al.   CHEMICAL REVIEWS

Structure Guided Design of Biotin Protein Ligase Inhibitors for Antibiotic Discovery

(2014) Ashleigh Paparella et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Nanomaterial-Induced Autophagy: A New Reversal MDR Tool in Cancer Therapy?

(2014) Elisa Panzarini et al.   MOLECULAR PHARMACEUTICS

Colocalized Delivery of Rapamycin and Paclitaxel to Tumors Enhances Synergistic Targeting of the PI3K/Akt/mTOR Pathway

(2014) Elvin Blanco et al.   MOLECULAR THERAPY

Drug delivery: Beyond active tumour targeting

(2014) Sharon M. Sagnella et al.   Nanomedicine-Nanotechnology Biology and Medicine

Remote regulation of glucose homeostasis in mice using genetically encoded nanoparticles

(2014) Sarah A Stanley et al.   NATURE MEDICINE

A Nanoparticle-Based Combination Chemotherapy Delivery System for Enhanced Tumor Killing by Dynamic Rewiring of Signaling Pathways

(2014) S. W. Morton et al.   Science Signaling

Structure-Dependent Mitochondrial Dysfunction and Hypoxia Induced with Single-Walled Carbon Nanotubes

(2014) Li-Rong Wang et al.   Small

Toxicity of Metal Oxide Nanoparticles: Mechanisms, Characterization, and Avoiding Experimental Artefacts

(2014) Aleksandra B. Djurišić et al.   Small

Graphene Oxide Triggers Toll-Like Receptors/Autophagy Responses In Vitro and Inhibits Tumor Growth In Vivo

(2014) Guan-Yu Chen et al.   Advanced Healthcare Materials

Nanoparticle–protein corona complexes govern the biological fates and functions of nanoparticles

(2014) Cindy Gunawan et al.   Journal of Materials Chemistry B

Drug-releasing implants: current progress, challenges and perspectives

(2014) Abel Santos et al.   Journal of Materials Chemistry B

Layer-by-Layer Nanoparticles for Systemic Codelivery of an Anticancer Drug and siRNA for Potential Triple-Negative Breast Cancer Treatment

(2013) Zhou J. Deng et al.   ACS Nano

Emerging methods for the fabrication of polymer capsules

(2013) Jiwei Cui et al.   ADVANCES IN COLLOID AND INTERFACE SCIENCE

The role of elevated autophagy on the synaptic plasticity impairment caused by CdSe/ZnS quantum dots

(2013) Liang Chen et al.   BIOMATERIALS

Amino-functionalized nanoparticles as inhibitors of mTOR and inducers of cell cycle arrest in leukemia cells

(2013) Cornelia Loos et al.   BIOMATERIALS

The effect of autophagy inhibitors on drug delivery using biodegradable polymer nanoparticles in cancer treatment

(2013) Xudong Zhang et al.   BIOMATERIALS

Advanced nuclear analytical and related techniques for the growing challenges in nanotoxicology

(2013) Chunying Chen et al.   CHEMICAL SOCIETY REVIEWS

Genotyping and Genomic Profiling of Non–Small-Cell Lung Cancer: Implications for Current and Future Therapies

(2013) Tianhong Li et al.   JOURNAL OF CLINICAL ONCOLOGY

Drug Delivery Interfaces in the 21st Century: From Science Fiction Ideas to Viable Technologies

(2013) Beata Chertok et al.   MOLECULAR PHARMACEUTICS

Anthracycline nano-delivery systems to overcome multiple drug resistance: A comprehensive review

(2013) Ping Ma et al.   Nano Today

Next-generation nanomedicines and nanosimilars: EU regulators’ initiatives relating to the development and evaluation of nanomedicines

(2013) Falk Ehmann et al.   Nanomedicine

Mechanisms of genotoxicity. A review ofin vitroandin vivostudies with engineered nanoparticles

(2013) Zuzana Magdolenova et al.   Nanotoxicology

Stimuli-responsive nanocarriers for drug delivery

(2013) Simona Mura et al.   NATURE MATERIALS

Engineering synthetic vaccines using cues from natural immunity

(2013) Darrell J. Irvine et al.   NATURE MATERIALS

Multiwall Carbon Nanotubes Mediate Macrophage Activation and Promote Pulmonary Fibrosis Through TGF-β/Smad Signaling Pathway

(2013) Peng Wang et al.   Small

Accumulated Polymer Degradation Products as Effector Molecules in Cytotoxicity of Polymeric Nanoparticles

(2013) Raman Preet Singh et al.   TOXICOLOGICAL SCIENCES

IRE1: ER stress sensor and cell fate executor

(2013) Yani Chen et al.   TRENDS IN CELL BIOLOGY

Non-eroding drug-releasing implants with ordered nanoporous and nanotubular structures: concepts for controlling drug release

(2013) Moom Sinn Aw et al.   Biomaterials Science

Nanomaterial Toxicity Testing in the 21st Century: Use of a Predictive Toxicological Approach and High-Throughput Screening

(2012) Andre Nel et al.   ACCOUNTS OF CHEMICAL RESEARCH

Programmed Cell Death: Molecular Mechanisms and Implications for Safety Assessment of Nanomaterials

(2012) Fernando Torres Andón et al.   ACCOUNTS OF CHEMICAL RESEARCH

Size-Dependent Localization and Penetration of Ultrasmall Gold Nanoparticles in Cancer Cells, Multicellular Spheroids, and Tumors in Vivo

(2012) Keyang Huang et al.   ACS Nano

Pegylated Phospholipid Micelles Induce Endoplasmic Reticulum-Dependent Apoptosis of Cancer Cells but not Normal Cells

(2012) Jing Wang et al.   ACS Nano

Influence of Geometry, Porosity, and Surface Characteristics of Silica Nanoparticles on Acute Toxicity: Their Vasculature Effect and Tolerance Threshold

(2012) Tian Yu et al.   ACS Nano

Engineering Particles for Therapeutic Delivery: Prospects and Challenges

(2012) Yan Yan et al.   ACS Nano

Designed Synthesis of CeO2 Nanorods and Nanowires for Studying Toxicological Effects of High Aspect Ratio Nanomaterials

(2012) Zhaoxia Ji et al.   ACS Nano

MnO Nanocrystals: A Platform for Integration of MRI and Genuine Autophagy Induction for Chemotherapy

(2012) Yang Lu et al.   ADVANCED FUNCTIONAL MATERIALS

Simultaneous induction of autophagy and toll-like receptor signaling pathways by graphene oxide

(2012) Guan-Yu Chen et al.   BIOMATERIALS

Sequential Application of Anticancer Drugs Enhances Cell Death by Rewiring Apoptotic Signaling Networks

(2012) Michael J. Lee et al.   CELL

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

Cationic polymers and their therapeutic potential

(2012) Sangram Keshari Samal et al.   CHEMICAL SOCIETY REVIEWS

Doxil® — The first FDA-approved nano-drug: Lessons learned

(2012) Yechezkel (Chezy) Barenholz   JOURNAL OF CONTROLLED RELEASE

Pulmonary Toxicity, Distribution, and Clearance of Intratracheally Instilled Silicon Nanowires in Rats

(2012) Jenny R. Roberts et al.   Journal of Nanomaterials

Restoring Basal Planes of Graphene Oxides for Highly Efficient Loading and Delivery of β-Lapachone

(2012) Xin Ting Zheng et al.   MOLECULAR PHARMACEUTICS

Uptake and Transfection with Polymeric Nanoparticles Are Dependent on Polymer End-Group Structure, but Largely Independent of Nanoparticle Physical and Chemical Properties

(2012) Joel C. Sunshine et al.   MOLECULAR PHARMACEUTICS

Autophagy is involved in nanoalumina-induced cerebrovascular toxicity

(2012) Lei Chen et al.   Nanomedicine-Nanotechnology Biology and Medicine

Proof of concept for next-generation nanoparticle drugs in humans

(2012) Cormac Sheridan   NATURE BIOTECHNOLOGY

Magnetoferritin nanoparticles for targeting and visualizing tumour tissues

(2012) Kelong Fan et al.   Nature Nanotechnology

Biomolecular coronas provide the biological identity of nanosized materials

(2012) Marco P. Monopoli et al.   Nature Nanotechnology

Autophagy modulation as a potential therapeutic target for diverse diseases

(2012) David C. Rubinsztein et al.   NATURE REVIEWS DRUG DISCOVERY

Use of back-scatter electron signals to visualise cell/nanowires interactions in vitro and in vivo; frustrated phagocytosis of long fibres in macrophages and compartmentalisation in mesothelial cells in vivo

(2012) Anja Schinwald et al.   Particle and Fibre Toxicology

Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity

(2012) Stephan T Stern et al.   Particle and Fibre Toxicology

Topical delivery of siRNA-based spherical nucleic acid nanoparticle conjugates for gene regulation

(2012) Dan Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Radio-Wave Heating of Iron Oxide Nanoparticles Can Regulate Plasma Glucose in Mice

(2012) S. A. Stanley et al.   SCIENCE

Engineering Approaches to Immunotherapy

(2012) M. A. Swartz et al.   Science Translational Medicine

Preclinical Development and Clinical Translation of a PSMA-Targeted Docetaxel Nanoparticle with a Differentiated Pharmacological Profile

(2012) J. Hrkach et al.   Science Translational Medicine

Implementation of a Multidisciplinary Approach to Solve Complex Nano EHS Problems by the UC Center for the Environmental Implications of Nanotechnology

(2012) Tian Xia et al.   Small

NLRP3 Inflammasome Activation Induced by Engineered Nanomaterials

(2012) Bingbing Sun et al.   Small

Size-dependent toxicity and cell interaction mechanisms of gold nanoparticles on mouse fibroblasts

(2012) Rosella Coradeghini et al.   TOXICOLOGY LETTERS

Immunotoxicological impact of engineered nanomaterial exposure: mechanisms of immune cell modulation

(2012) Xiaojia Wang et al.   TOXICOLOGY MECHANISMS AND METHODS

Gold Nanorods Conjugated with Doxorubicin and cRGD for Combined Anticancer Drug Delivery and PET Imaging

(2012) Yuling Xiao et al.   Theranostics

Composites of Aminodextran-Coated Fe3O4 Nanoparticles and Graphene Oxide for Cellular Magnetic Resonance Imaging

(2011) Weihong Chen et al.   ACS Applied Materials & Interfaces

Interactions between Magnetic Nanowires and Living Cells: Uptake, Toxicity, and Degradation

(2011) Malak Safi et al.   ACS Nano

Identification of the Nanogold Particle-Induced Endoplasmic Reticulum Stress by Omic Techniques and Systems Biology Analysis

(2011) Yen-Yin Tsai et al.   ACS Nano

Protein Corona-Mediated Mitigation of Cytotoxicity of Graphene Oxide

(2011) Wenbing Hu et al.   ACS Nano

Doxorubicin-Tethered Responsive Gold Nanoparticles Facilitate Intracellular Drug Delivery for Overcoming Multidrug Resistance in Cancer Cells

(2011) Feng Wang et al.   ACS Nano

Gold Nanoparticles Induce Autophagosome Accumulation through Size-Dependent Nanoparticle Uptake and Lysosome Impairment

(2011) Xiaowei Ma et al.   ACS Nano

Water-Soluble Poly(N-isopropylacrylamide)-Graphene Sheets Synthesized via Click Chemistry for Drug Delivery

(2011) Yongzheng Pan et al.   ADVANCED FUNCTIONAL MATERIALS

Nanotoxicology: An Interdisciplinary Challenge

(2011) Harald F. Krug et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The association of autophagy with polyethylenimine-induced cytotoxity in nephritic and hepatic cell lines

(2011) Xiaoling Gao et al.   BIOMATERIALS

Regulation of stem cell signaling by nanoparticle-mediated intracellular protein delivery

(2011) Dhiral A. Shah et al.   BIOMATERIALS

Lysosomal membrane destabilization induced by high accumulation of single-walled carbon nanohorns in murine macrophage RAW 264.7

(2011) Yoshio Tahara et al.   BIOMATERIALS

Multi-functional graphene as an in vitro and in vivo imaging probe

(2011) Ganesh Gollavelli et al.   BIOMATERIALS

Induction of ROS, mitochondrial damage and autophagy in lung epithelial cancer cells by iron oxide nanoparticles

(2011) Mohd Imran Khan et al.   BIOMATERIALS

Graphene-based composites

(2011) Xiao Huang et al.   CHEMICAL SOCIETY REVIEWS

Drug delivery strategies for poorly water-soluble drugs: the industrial perspective

(2011) Peter van Hoogevest et al.   Expert Opinion on Drug Delivery

Nanoparticle delivery of a peptide targeting EGFR signaling

(2011) Sang Kyoon Kim et al.   JOURNAL OF CONTROLLED RELEASE

Drug targeting to tumors: Principles, pitfalls and (pre-) clinical progress

(2011) Twan Lammers et al.   JOURNAL OF CONTROLLED RELEASE

Polyethylenimine-functionalized graphene oxide as an efficient gene delivery vector

(2011) Biao Chen et al.   JOURNAL OF MATERIALS CHEMISTRY

Nanoparticle Size and Surface Chemistry Determine Serum Protein Adsorption and Macrophage Uptake

(2011) Carl D. Walkey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Controlled release of drug from folate-decorated and graphene mediated drug delivery system: Synthesis, loading efficiency, and drug release response

(2011) D. Depan et al.   Materials Science & Engineering C-Materials for Biological Applications

The Role of Autophagy in Cancer: Therapeutic Implications

(2011) Z. J. Yang et al.   MOLECULAR CANCER THERAPEUTICS

Intracellular Targeting of PLGA Nanoparticles Encapsulating Antigenic Peptide to the Endoplasmic Reticulum of Dendritic Cells and Its Effect on Antigen Cross-Presentationin Vitro

(2011) Hadas Sneh-Edri et al.   MOLECULAR PHARMACEUTICS

Liposome-Encapsulated Doxorubicin Reverses Drug Resistance by Inhibiting P-Glycoprotein in Human Cancer Cells

(2011) Chiara Riganti et al.   MOLECULAR PHARMACEUTICS

Cancer-Targeted Optical Imaging with Fluorescent Zinc Oxide Nanowires

(2011) Hao Hong et al.   NANO LETTERS

Minimizing Oxidation and Stable Nanoscale Dispersion Improves the Biocompatibility of Graphene in the Lung

(2011) Matthew C. Duch et al.   NANO LETTERS

Emerging nanomaterials for targeting subcellular organelles

(2011) Jasper G. Huang et al.   Nano Today

Gold-doxorubicin nanoconjugates for overcoming multidrug resistance

(2011) Yan-Juan Gu et al.   Nanomedicine-Nanotechnology Biology and Medicine

Mesoporous silica nanoparticles loading doxorubicin reverse multidrug resistance: performance and mechanism

(2011) Jianan Shen et al.   Nanoscale

Graphene based gene transfection

(2011) Liangzhu Feng et al.   Nanoscale

Length-dependent pathogenic effects of nickel nanowires in the lungs and the peritoneal cavity

(2011) Craig A. Poland et al.   Nanotoxicology

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Alpha-alumina nanoparticles induce efficient autophagy-dependent cross-presentation and potent antitumour response

(2011) Haiyan Li et al.   Nature Nanotechnology

Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn2+ dissolution inside lysosomes

(2011) Wan-Seob Cho et al.   Particle and Fibre Toxicology

Cationic Liposomal Co-delivery of Small Interfering RNA and a MEK Inhibitor for Enhanced Anticancer Efficacy

(2011) Seung Hee Kang et al.   PHARMACEUTICAL RESEARCH

Binding of blood proteins to carbon nanotubes reduces cytotoxicity

(2011) C. Ge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multistage nanoparticle delivery system for deep penetration into tumor tissue

(2011) C. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chitosan-Functionalized Graphene Oxide as a Nanocarrier for Drug and Gene Delivery

(2011) Hongqian Bao et al.   Small

Enhanced Chemotherapy Efficacy by Sequential Delivery of siRNA and Anticancer Drugs Using PEI-Grafted Graphene Oxide

(2011) Liming Zhang et al.   Small

Nanoparticle-Mediated Cytoplasmic Delivery of Proteins To Target Cellular Machinery

(2010) Shyam Sundhar Bale et al.   ACS Nano

pH-Dependent Toxicity of High Aspect Ratio ZnO Nanowires in Macrophages Due to Intracellular Dissolution

(2010) Karin H. Müller et al.   ACS Nano

Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives

(2010) Katrin Knop et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Au@Pt nanostructures as oxidase and peroxidase mimetics for use in immunoassays

(2010) Weiwei He et al.   BIOMATERIALS

Cancer nanotechnology: application of nanotechnology in cancer therapy

(2010) Ranjita Misra et al.   DRUG DISCOVERY TODAY

Oxidative stress, inflammation, and cancer: How are they linked?

(2010) Simone Reuter et al.   FREE RADICAL BIOLOGY AND MEDICINE

Multifunctional Nanoparticles Delivering Small Interfering RNA and Doxorubicin Overcome Drug Resistance in Cancer

(2010) Yunching Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting of drugs and nanoparticles to tumors

(2010) Erkki Ruoslahti et al.   JOURNAL OF CELL BIOLOGY

Nuclear Targeting of Gold Nanoparticles in Cancer Cells Induces DNA Damage, Causing Cytokinesis Arrest and Apoptosis

(2010) Bin Kang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and Drug-Delivery Behavior of Chitosan-Functionalized Graphene Oxide Hybrid Nanosheets

(2010) Vijay Kumar Rana et al.   MACROMOLECULAR MATERIALS AND ENGINEERING

Dual Inhibition of Akt/Mammalian Target of Rapamycin Pathway byNanoparticle Albumin-Bound–Rapamycin and Perifosine Induces Antitumor Activity in Multiple Myeloma

(2010) Diana Cirstea et al.   MOLECULAR CANCER THERAPEUTICS

The Art of Engineering Viral Nanoparticles

(2010) Jonathan K. Pokorski et al.   MOLECULAR PHARMACEUTICS

Nanoparticles Modified With Tumor-targeting scFv Deliver siRNA and miRNA for Cancer Therapy

(2010) Yunching Chen et al.   MOLECULAR THERAPY

Facile synthesis and application of Ag-chemically converted graphene nanocomposite

(2010) Jianfeng Shen et al.   Nano Research

Rapid translocation of nanoparticles from the lung airspaces to the body

(2010) Hak Soo Choi et al.   NATURE BIOTECHNOLOGY

Can autophagy promote longevity?

(2010) Frank Madeo et al.   NATURE CELL BIOLOGY

Remote control of ion channels and neurons through magnetic-field heating of nanoparticles

(2010) Heng Huang et al.   Nature Nanotechnology

Delivering nanomedicine to solid tumors

(2010) Rakesh K. Jain et al.   Nature Reviews Clinical Oncology

Nanomaterial cytotoxicity is composition, size, and cell type dependent

(2010) Syed K Sohaebuddin et al.   Particle and Fibre Toxicology

Clinical Developments in Nanotechnology for Cancer Therapy

(2010) Jeremy D. Heidel et al.   PHARMACEUTICAL RESEARCH

A Predictive Toxicological Paradigm for the Safety Assessment of Nanomaterials

(2009) Huan Meng et al.   ACS Nano

Impact of Nanotechnology on Drug Delivery

(2009) Omid C. Farokhzad et al.   ACS Nano

Nanoparticle-mediated targeting of phosphatidylinositol-3-kinase signaling inhibits angiogenesis

(2009) Rania Harfouche et al.   ANGIOGENESIS

NanoGenotoxicology: The DNA damaging potential of engineered nanomaterials

(2009) Neenu Singh et al.   BIOMATERIALS

Fullerene Exposures with Oysters: Embryonic, Adult, and Cellular Responses

(2009) Amy H. Ringwood et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Self-ordered nanopore and nanotube platforms for drug delivery applications

(2009) Dusan Losic et al.   Expert Opinion on Drug Delivery

Nanosystem drug targeting: Facing up to complex realities

(2009) Pakatip Ruenraroengsak et al.   JOURNAL OF CONTROLLED RELEASE

Superparamagnetic graphene oxide–Fe3O4 nanoparticles hybrid for controlled targeted drug carriers

(2009) Xiaoying Yang et al.   JOURNAL OF MATERIALS CHEMISTRY

Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection

(2009) Luc English et al.   NATURE IMMUNOLOGY

Understanding biophysicochemical interactions at the nano–bio interface

(2009) Andre E. Nel et al.   NATURE MATERIALS

Inhaled carbon nanotubes reach the subpleural tissue in mice

(2009) Jessica P. Ryman-Rasmussen et al.   Nature Nanotechnology

Evaluation of nanoparticle immunotoxicity

(2009) Marina A. Dobrovolskaia et al.   Nature Nanotechnology

Nanoparticle-mediated targeting of MAPK signaling predisposes tumor to chemotherapy

(2009) S. Basu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biodegradable dendritic positron-emitting nanoprobes for the noninvasive imaging of angiogenesis

(2009) Adah Almutairi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular Uptake and Cytotoxicity of Gold Nanorods: Molecular Origin of Cytotoxicity and Surface Effects

(2009) Alaaldin M. Alkilany et al.   Small

Gold Nanoparticles of Diameter 1.4 nm Trigger Necrosis by Oxidative Stress and Mitochondrial Damage

(2009) Yu Pan et al.   Small

Comparison of the Mechanism of Toxicity of Zinc Oxide and Cerium Oxide Nanoparticles Based on Dissolution and Oxidative Stress Properties

(2008) Tian Xia et al.   ACS Nano

Cytotoxicity and Genotoxicity of Silver Nanoparticles in Human Cells

(2008) P. V. AshaRani et al.   ACS Nano

Efficient Cross-presentation Depends on Autophagy in Tumor Cells

(2008) Y. Li et al.   CANCER RESEARCH

Dual-modality optical and positron emission tomography imaging of vascular endothelial growth factor receptor on tumor vasculature using quantum dots

(2008) Kai Chen et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

PET/MRI Dual-Modality Tumor Imaging Using Arginine-Glycine-Aspartic (RGD)-Conjugated Radiolabeled Iron Oxide Nanoparticles

(2008) H.-Y. Lee et al.   JOURNAL OF NUCLEAR MEDICINE

PEGylated Nanographene Oxide for Delivery of Water-Insoluble Cancer Drugs

(2008) Zhuang Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles

(2008) Frank Alexis et al.   MOLECULAR PHARMACEUTICS

Organelle-Targeted Nanocarriers: Specific Delivery of Liposomal Ceramide to Mitochondria Enhances Its Cytotoxicity in Vitro and in Vivo

(2008) Sarathi V. Boddapati et al.   NANO LETTERS

Nano-graphene oxide for cellular imaging and drug delivery

(2008) Xiaoming Sun et al.   Nano Research

Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats

(2008) Michelle Longmire et al.   Nanomedicine

Genotoxicity of engineered nanomaterials: A critical review

(2008) Laetitia Gonzalez et al.   Nanotoxicology

Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study

(2008) Craig A. Poland et al.   Nature Nanotechnology

Preparation of peptide-conjugated quantum dots for tumor vasculature-targeted imaging

(2008) Weibo Cai et al.   Nature Protocols

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

(2008) Inki Kim et al.   NATURE REVIEWS DRUG DISCOVERY

Lysosomal membrane permeabilization in cell death

(2008) P Boya et al.   ONCOGENE

The effect of particle design on cellular internalization pathways

(2008) S. E. A. Gratton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MITO-Porter: A liposome-based carrier system for delivery of macromolecules into mitochondria via membrane fusion

(2007) Yuma Yamada et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES