Prion Infections and Anti-PrP Antibodies Trigger Converging Neurotoxic Pathways

Role of autophagy in prion protein-induced neurodegenerative diseases

(2013) H. Yao et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein

(2013) Tiziana Sonati et al.   NATURE

PDK1 decreases TACE-mediated α-secretase activity and promotes disease progression in prion and Alzheimer's diseases

(2013) Mathéa Pietri et al.   NATURE MEDICINE

Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice

(2013) J. A. Moreno et al.   Science Translational Medicine

Structural studies on the folded domain of the human prion protein bound to the Fab fragment of the antibody POM1

(2012) Pravas Kumar Baral et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Detection of reactive oxygen species derived from the family of NOX NADPH oxidases

(2012) Ghassan J. Maghzal et al.   FREE RADICAL BIOLOGY AND MEDICINE

Early Cytokine Elevation, PrPres Deposition, and Gliosis in Mouse Scrapie: No Effect on Disease by Deletion of Cytokine Genes IL-12p40 and IL-12p35

(2012) D. Tribouillard-Tanvier et al.   JOURNAL OF VIROLOGY

Prion Pathogenesis Is Faithfully Reproduced in Cerebellar Organotypic Slice Cultures

(2012) Jeppe Falsig et al.   PLoS Pathogens

Crystallization and preliminary X-ray diffraction analysis of prion protein bound to the Fab fragment of the POM1 antibody

(2011) Pravas Kumar Baral et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication

(2011) Ulrike K Resenberger et al.   EMBO JOURNAL

In cardiac myoblasts, cellular redox regulates FosB and Fra-1 through multiple cis-regulatory modules

(2011) Ekta Jindal et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hydroxytyrosol: from laboratory investigations to future clinical trials

(2010) Sergio Granados-Principal et al.   NUTRITION REVIEWS

Prion Protein Misfolding Affects Calcium Homeostasis and Sensitizes Cells to Endoplasmic Reticulum Stress

(2010) Mauricio Torres et al.   PLoS One

Autophagy induction by trehalose counter-acts cellular prion-infection

(2009) Yasmine Aguib et al.   Autophagy

NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation

(2009) Angela M Brennan et al.   NATURE NEUROSCIENCE

Prion protein attenuates excitotoxicity by inhibiting NMDA receptors

(2008) Houman Khosravani et al.   JOURNAL OF CELL BIOLOGY

Direct multiplexed measurement of gene expression with color-coded probe pairs

(2008) Gary K Geiss et al.   NATURE BIOTECHNOLOGY

The prion organotypic slice culture assay—POSCA

(2008) Jeppe Falsig et al.   Nature Protocols

The POM Monoclonals: A Comprehensive Set of Antibodies to Non-Overlapping Prion Protein Epitopes

(2008) Magdalini Polymenidou et al.   PLoS One