Structural studies on the folded domain of the human prion protein bound to the Fab fragment of the antibody POM1

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Antigen–antibody interface properties: Composition, residue interactions, and features of 53 non-redundant structures

(2012) Thiruvarangan Ramaraj et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

PrP Antibodies Do Not Trigger Mouse Hippocampal Neuron Apoptosis

(2012) P.-C. Klohn et al.   SCIENCE

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Crystallization and preliminary X-ray diffraction analysis of prion protein bound to the Fab fragment of the POM1 antibody

(2011) Pravas Kumar Baral et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Structural organization of brain-derived mammalian prions examined by hydrogen-deuterium exchange

(2011) Vytautas Smirnovas et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites

(2011) Darragh B. Freir et al.   Nature Communications

Prion protein and Aβ-related synaptic toxicity impairment

(2010) Anna Maria Calella et al.   EMBO Molecular Medicine

The prion protein as a receptor for amyloid-β

(2010) Helmut W. Kessels et al.   NATURE

Pharmacological chaperone for the structured domain of human prion protein

(2010) Andrew J. Nicoll et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular replacement withMOLREP

(2009) Alexei Vagin et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Conformational diversity in prion protein variants influences intermolecular β-sheet formation

(2009) Seungjoo Lee et al.   EMBO JOURNAL

Conformational Properties of β-PrP

(2009) Laszlo L. P. Hosszu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of human prion protein bound to a therapeutic antibody

(2009) S. V. Antonyuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Variety of Antiprion Compounds Discovered through an In Silico Screen Based on Cellular-Form Prion Protein Structure: Correlation between Antiprion Activity and Binding Affinity

(2008) J. Hosokawa-Muto et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The POM Monoclonals: A Comprehensive Set of Antibodies to Non-Overlapping Prion Protein Epitopes

(2008) Magdalini Polymenidou et al.   PLoS One

De novo generation of a transmissible spongiform encephalopathy by mouse transgenesis

(2008) C. J. Sigurdson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA