Prion Protein Misfolding Affects Calcium Homeostasis and Sensitizes Cells to Endoplasmic Reticulum Stress

Endoplasmic reticulum Ca2+ increases enhance mutant glucocerebrosidase proteostasis

(2010) Derrick Sek Tong Ong et al.   Nature Chemical Biology

The ER and ageing II: Calcium homeostasis

(2009) Monika Puzianowska-Kuznicka et al.   AGEING RESEARCH REVIEWS

BAX Inhibitor-1 Is a Negative Regulator of the ER Stress Sensor IRE1α

(2009) Fernanda Lisbona et al.   MOLECULAR CELL

Fine-Tuning of the Unfolded Protein Response: Assembling the IRE1α Interactome

(2009) Claudio Hetz et al.   MOLECULAR CELL

De Novo Generation of Infectious Prions In Vitro Produces a New Disease Phenotype

(2009) Marcelo A. Barria et al.   PLoS Pathogens

The Stress Rheostat: An Interplay Between the Unfolded Protein Response (UPR) and Autophagy in Neurodegeneration

(2008) Soledad Matus et al.   CURRENT MOLECULAR MEDICINE

Reduced Translocation of Nascent Prion Protein During ER Stress Contributes to Neurodegeneration

(2008) Neena S. Rane et al.   DEVELOPMENTAL CELL

BI-1 Regulates Endoplasmic Reticulum Ca2+Homeostasis Downstream of Bcl-2 Family Proteins

(2008) Chunyan Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The release of calcium from the endoplasmic reticulum induced by amyloid-beta and prion peptides activates the mitochondrial apoptotic pathway

(2008) Elisabete Ferreiro et al.   NEUROBIOLOGY OF DISEASE

Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis

(2008) C. Hetz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA