The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication

Aberrant Amyloid Precursor Protein (APP) Processing in Hereditary Forms of Alzheimer Disease Caused by APP Familial Alzheimer Disease Mutations Can Be Rescued by Mutations in the APP GxxxG Motif

(2010) Lisa-Marie Munter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Memory Impairment in Transgenic Alzheimer Mice Requires Cellular Prion Protein

(2010) D. A. Gimbel et al.   JOURNAL OF NEUROSCIENCE

Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

(2010) Jorge J Palop et al.   NATURE NEUROSCIENCE

Proteases and Proteolysis in Alzheimer Disease: A Multifactorial View on the Disease Process

(2010) Bart De Strooper   PHYSIOLOGICAL REVIEWS

Close encounters of the third kind: disordered domains and the interactions of proteins

(2009) Peter Tompa et al.   BIOESSAYS

α-Helical Domains Promote Translocation of Intrinsically Disordered Polypeptides into the Endoplasmic Reticulum

(2009) Margit Miesbauer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Non–cell autonomous toxicity in neurodegenerative disorders: ALS and beyond

(2009) Hristelina Ilieva et al.   JOURNAL OF CELL BIOLOGY

Role of Amyloid-  Glycine 33 in Oligomerization, Toxicity, and Neuronal Plasticity

(2009) A. Harmeier et al.   JOURNAL OF NEUROSCIENCE

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers

(2009) Juha Laurén et al.   NATURE

Alzheimer’s Disease Amyloid β-Protein and Synaptic Function

(2009) Tomas Ondrejcak et al.   NEUROMOLECULAR MEDICINE

The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases

(2008) Konstanze F Winklhofer et al.   EMBO JOURNAL

Stress-protective signalling of prion protein is corrupted by scrapie prions

(2008) Angelika S Rambold et al.   EMBO JOURNAL

Prion protein attenuates excitotoxicity by inhibiting NMDA receptors

(2008) Houman Khosravani et al.   JOURNAL OF CELL BIOLOGY