Extremely High Mutation Rate of HIV-1 In Vivo

Requirement of HIV-1 Vif C-terminus for Vif-CBF-β interaction and assembly of CUL5-containing E3 ligase

(2014) Hong Wang et al.   BMC MICROBIOLOGY

RNA Virus Population Diversity, an Optimum for Maximal Fitness and Virulence

(2014) Victoria K. Korboukh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Uneven Genetic Robustness of HIV-1 Integrase

(2014) Suzannah J. Rihn et al.   JOURNAL OF VIROLOGY

Attenuation of Human Enterovirus 71 High-Replication-Fidelity Variants in AG129 Mice

(2014) T. Meng et al.   JOURNAL OF VIROLOGY

MOSAIK: A Hash-Based Algorithm for Accurate Next-Generation Sequencing Short-Read Mapping

(2014) Wan-Ping Lee et al.   PLoS One

Positioning of APOBEC3G/F Mutational Hotspots in the Human Immunodeficiency Virus Genome Favors Reduced Recognition by CD8+ T Cells

(2014) Mahdis Monajemi et al.   PLoS One

Virulence and Pathogenesis of HIV-1 Infection: An Evolutionary Perspective

(2014) C. Fraser et al.   SCIENCE

Natural Polymorphisms in Human APOBEC3H and HIV-1 Vif Combine in Primary T Lymphocytes to Affect Viral G-to-A Mutation Levels and Infectivity

(2014) Eric W. Refsland et al.   PLoS Genetics

AID and APOBECs span the gap between innate and adaptive immunity

(2014) Arnaud Moris et al.   Frontiers in Microbiology

Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure

(2013) Ya-Chi Ho et al.   CELL

HIV-1 Vif Adaptation to Human APOBEC3H Haplotypes

(2013) Marcel Ooms et al.   Cell Host & Microbe

Correlation Between Mutation Rate and Genome Size in Riboviruses: Mutation Rate of Bacteriophage Q 

(2013) K. Bradwell et al.   GENETICS

Multiple APOBEC3 Restriction Factors for HIV-1 and One Vif to Rule Them All

(2013) Belete A. Desimmie et al.   JOURNAL OF MOLECULAR BIOLOGY

Variation of HIV-1 Mutation Spectra among Cell Types

(2013) C. M. Holtz et al.   JOURNAL OF VIROLOGY

The role of mutational robustness in RNA virus evolution

(2013) Adam S. Lauring et al.   NATURE REVIEWS MICROBIOLOGY

Elevated hypermutation levels in HIV-1 natural viral suppressors

(2013) Lindsay M. Eyzaguirre et al.   VIROLOGY

Extreme Genetic Fragility of the HIV-1 Capsid

(2013) Suzannah J. Rihn et al.   PLoS Pathogens

Host Factors and HIV-1 Replication: Clinical Evidence and Potential Therapeutic Approaches

(2013) Mariana Santa-Marta et al.   Frontiers in Immunology

Integrated HIV DNA accumulates prior to treatment while episomal HIV DNA records ongoing transmission afterwards

(2012) John M. Murray et al.   AIDS

E138K and M184I mutations in HIV-1 reverse transcriptase coemerge as a result of APOBEC3 editing in the absence of drug exposure

(2012) Slim Fourati et al.   AIDS

De novo assembly of highly diverse viral populations

(2012) Xiao Yang et al.   BMC GENOMICS

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

APOBEC3G expression and hypermutation are inversely associated with human immunodeficiency virus type 1 (HIV-1) burden in vivo

(2012) Yordanka Kourteva et al.   VIROLOGY

The origin of genetic diversity in HIV-1

(2012) Redmond P. Smyth et al.   VIRUS RESEARCH

APOBEC3G-Induced Hypermutation of Human Immunodeficiency Virus Type-1 Is Typically a Discrete “All or Nothing” Phenomenon

(2012) Andrew E. Armitage et al.   PLoS Genetics

Quantifying the Diversification of Hepatitis C Virus (HCV) during Primary Infection: Estimates of the In Vivo Mutation Rate

(2012) Ruy M. Ribeiro et al.   PLoS Pathogens

Whole Genome Deep Sequencing of HIV-1 Reveals the Impact of Early Minor Variants Upon Immune Recognition During Acute Infection

(2012) Matthew R. Henn et al.   PLoS Pathogens

Quality control and preprocessing of metagenomic datasets

(2011) R. Schmieder et al.   BIOINFORMATICS

The Activity Spectrum of Vif from Multiple HIV-1 Subtypes against APOBEC3G, APOBEC3F, and APOBEC3H

(2011) M. Binka et al.   JOURNAL OF VIROLOGY

Genetic Editing of Herpes Simplex Virus 1 and Epstein-Barr Herpesvirus Genomes by Human APOBEC3 Cytidine Deaminases in Culture and In Vivo

(2011) R. Suspene et al.   JOURNAL OF VIROLOGY

Analysis of Human APOBEC3H Haplotypes and Anti-Human Immunodeficiency Virus Type 1 Activity

(2011) X. Wang et al.   JOURNAL OF VIROLOGY

Expression of APOBEC3G/3F and G-to-A Hypermutation Levels in HIV-1-Infected Children with Different Profiles of Disease Progression

(2011) Nívea D. Amoêdo et al.   PLoS One

Arbovirus high fidelity variant loses fitness in mosquitoes and mice

(2011) L. L. Coffey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Viral Mutation Rates

(2010) R. Sanjuan et al.   JOURNAL OF VIROLOGY

APOBEC3G Contributes to HIV-1 Variation through Sublethal Mutagenesis

(2010) H. A. Sadler et al.   JOURNAL OF VIROLOGY

Nature, Position, and Frequency of Mutations Made in a Single Cycle of HIV-1 Replication

(2010) M. E. Abram et al.   JOURNAL OF VIROLOGY

Identifying genetic markers of adaptation for surveillance of viral host jumps

(2010) Kim M. Pepin et al.   NATURE REVIEWS MICROBIOLOGY

Relationship Between HIV Coreceptor Tropism and Disease Progression in Persons With Untreated Chronic HIV Infection

(2009) Matthew Bidwell Goetz et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Analysis of the Percentage of Human Immunodeficiency Virus Type 1 Sequences That Are Hypermutated and Markers of Disease Progression in a Longitudinal Cohort, Including One Individual with a Partially Defective Vif

(2009) A. Piantadosi et al.   JOURNAL OF VIROLOGY

Effect of Ribavirin on the Mutation Rate and Spectrum of Hepatitis C Virus In Vivo

(2009) J. M. Cuevas et al.   JOURNAL OF VIROLOGY

T-Cell Vaccine Strategies for Human Immunodeficiency Virus, the Virus with a Thousand Faces

(2009) B. T. Korber et al.   JOURNAL OF VIROLOGY

Understanding HIV-1 latency provides clues for the eradication of long-term reservoirs

(2009) Mayte Coiras et al.   NATURE REVIEWS MICROBIOLOGY

APOBEC3G induces a hypermutation gradient: purifying selection at multiple steps during HIV-1 replication results in levels of G-to-A mutations that are high in DNA, intermediate in cellular viral RNA, and low in virion RNA

(2009) Rebecca A Russell et al.   Retrovirology

The Spanish HIV BioBank: a model of cooperative HIV research

(2009) Isabel Garcia-Merino et al.   Retrovirology

Extremely High Mutation Rate of a Hammerhead Viroid

(2009) S. Gago et al.   SCIENCE

A combination of defective DNA and protective host factors are found in a set of HIV-1 ancestral LTNPs

(2009) Virginia Sandonís et al.   VIROLOGY

Mutation Rates and Intrinsic Fidelity of Retroviral Reverse Transcriptases

(2009) Luis Menéndez-Arias   Viruses-Basel

The Level of APOBEC3G (hA3G)-Related G-to-A Mutations Does Not Correlate with Viral Load in HIV Type 1-Infected Individuals

(2008) Nzovu K. Ulenga et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Dynamics of Total, Linear Nonintegrated, and Integrated HIV‐1 DNA In Vivo and In Vitro

(2008) Kersten K. Koelsch et al.   JOURNAL OF INFECTIOUS DISEASES

End-point limiting-dilution real-time PCR assay for evaluation of hepatitis C virus quasispecies in serum: Performance under optimal and suboptimal conditions

(2008) Sumathi Ramachandran et al.   JOURNAL OF VIROLOGICAL METHODS

Conserved Footprints of APOBEC3G on Hypermutated Human Immunodeficiency Virus Type 1 and Human Endogenous Retrovirus HERV-K(HML2) Sequences

(2008) A. E. Armitage et al.   JOURNAL OF VIROLOGY

Deciphering Human Immunodeficiency Virus Type 1 Transmission and Early Envelope Diversification by Single-Genome Amplification and Sequencing

(2008) J. F. Salazar-Gonzalez et al.   JOURNAL OF VIROLOGY

Engineering attenuated virus vaccines by controlling replication fidelity

(2008) Marco Vignuzzi et al.   NATURE MEDICINE

Inversing the natural hydrogen bonding rule to selectively amplify GC-rich ADAR-edited RNAs

(2008) Rodolphe Suspène et al.   NUCLEIC ACIDS RESEARCH

Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection

(2008) B. F. Keele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for Editing of Human Papillomavirus DNA by APOBEC3 in Benign and Precancerous Lesions

(2008) J.-P. Vartanian et al.   SCIENCE

Rates of HIV immune escape and reversion: implications for vaccination

(2008) Miles P. Davenport et al.   TRENDS IN MICROBIOLOGY

Variable contexts and levels of hypermutation in HIV-1 proviral genomes recovered from primary peripheral blood mononuclear cells

(2008) Gustavo H. Kijak et al.   VIROLOGY