A new look at sodium channel   subunits

Brugada Syndrome Disease Phenotype Explained in Apparently Benign Sodium Channel Mutations

(2014) M. Hoshi et al.   Circulation-Cardiovascular Genetics

Crystal Structure and Molecular Imaging of the NavChannel β3 Subunit Indicates a Trimeric Assembly

(2014) Sivakumar Namadurai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Advantages of proteins being disordered

(2014) Zhirong Liu et al.   PROTEIN SCIENCE

Domain IV voltage-sensor movement is both sufficient and rate limiting for fast inactivation in sodium channels

(2013) Deborah L. Capes et al.   JOURNAL OF GENERAL PHYSIOLOGY

Na+ Channel-Dependent Recruitment of Nav 4 to Axon Initial Segments and Nodes of Ranvier

(2013) S. A. Buffington et al.   JOURNAL OF NEUROSCIENCE

Identification of Navβ1 Residues Involved in the Modulation of the Sodium Channel Nav1.4

(2013) Angel A. Islas et al.   PLoS One

Crystallographic insights into sodium-channel modulation by the  4 subunit

(2013) J. Gilchrist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Allostery and the Monod-Wyman-Changeux Model After 50 Years

(2012) Jean-Pierre Changeux   Annual Review of Biophysics

Co-expression of NaVβ subunits alters the kinetics of inhibition of voltage-gated sodium channels by pore-blocking μ-conotoxins

(2012) Min-Min Zhang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Dominant-negative effect of SCN5A N-terminal mutations through the interaction of Nav1.5 α-subunits

(2012) Jérôme Clatot et al.   CARDIOVASCULAR RESEARCH

Novel SCN3B Mutation Associated With Brugada Syndrome Affects Intracellular Trafficking and Function of Nav1.5

(2012) Taisuke Ishikawa et al.   CIRCULATION JOURNAL

The immunoglobulin domain of the sodium channel β3 subunit contains a surface-localized disulfide bond that is required for homophilic binding

(2012) Nikitha R. Yereddi et al.   FASEB JOURNAL

Identification of the Cysteine Residue Responsible for Disulfide Linkage of Na+Channel α and β2 Subunits

(2012) Chunling Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations

(2012) Ernesto Vargas et al.   JOURNAL OF GENERAL PHYSIOLOGY

Sodium channels, the electrogenisome and the electrogenistat: lessons and questions from the clinic

(2012) Stephen G. Waxman   JOURNAL OF PHYSIOLOGY-LONDON

Voltage-gated sodium channels at 60: structure, function and pathophysiology

(2012) William A. Catterall   JOURNAL OF PHYSIOLOGY-LONDON

Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel

(2012) Xu Zhang et al.   NATURE

The β1-Subunit of Nav1.5 Cardiac Sodium Channel Is Required for a Dominant Negative Effect through α-α Interaction

(2012) Aurélie Mercier et al.   PLoS One

Structure of a bacterial voltage-gated sodium channel pore reveals mechanisms of opening and closing

(2012) Emily C. McCusker et al.   Nature Communications

Regulation of Nav1.6 and Nav1.8 peripheral nerve Na+ channels by auxiliary β-subunits

(2011) Juan Zhao et al.   JOURNAL OF NEUROPHYSIOLOGY

Cross-Species Conservation of Open-Channel Block by Na Channel  4 Peptides Reveals Structural Features Required for Resurgent Na Current

(2011) A. H. Lewis et al.   JOURNAL OF NEUROSCIENCE

NaV  Subunits Modulate the Inhibition of NaV1.8 by the Analgesic Gating Modifier  O-Conotoxin MrVIB

(2011) M. J. Wilson et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The crystal structure of a voltage-gated sodium channel

(2011) Jian Payandeh et al.   NATURE

Na+ Channel ? Subunits: Overachievers of the Ion Channel Family

(2011) William J. Brackenbury et al.   Frontiers in Pharmacology

Functional dominant-negative mutation of sodium channel subunit gene SCN3B associated with atrial fibrillation in a Chinese GeneID population

(2010) Pengyun Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

New mutation c.374C>T and a putative disease-associated haplotype within SCN1B gene in Tunisian families with febrile seizures

(2010) N. Fendri-Kriaa et al.   EUROPEAN JOURNAL OF NEUROLOGY

Sudden infant death syndrome–associated mutations in the sodium channel beta subunits

(2010) Bi-Hua Tan et al.   HEART RHYTHM

The Sodium Channel β3-Subunit Induces Multiphasic Gating in NaV1.3 and Affects Fast Inactivation via Distinct Intracellular Regions

(2010) Fiona S. Cusdin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Electrophysiology and beyond: Multiple roles of Na+ channel β subunits in development and disease

(2010) Gustavo A. Patino et al.   NEUROSCIENCE LETTERS

Determinants of voltage-gated sodium channel clustering in neurons

(2010) Christophe Leterrier et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Scn3b knockout mice exhibit abnormal sino-atrial and cardiac conduction properties

(2009) P. Hakim et al.   Acta Physiologica

Loss-of-function mutation of the SCN3B-encoded sodium channel  3 subunit associated with a case of idiopathic ventricular fibrillation

(2009) C. R. Valdivia et al.   CARDIOVASCULAR RESEARCH

Hippocampal Navβ3 expression in patients with temporal lobe epilepsy

(2009) Koen L. I. van Gassen et al.   EPILEPSIA

A Functional Null Mutation of SCN1B in a Patient with Dravet Syndrome

(2009) G. A. Patino et al.   JOURNAL OF NEUROSCIENCE

Regulation of Persistent Na Current by Interactions between   Subunits of Voltage-Gated Na Channels

(2009) T. K. Aman et al.   JOURNAL OF NEUROSCIENCE

The voltage-gated Na+ channel β3 subunit does not mediate trans homophilic cell adhesion or associate with the cell adhesion molecule contactin

(2009) Dyke P. McEwen et al.   NEUROSCIENCE LETTERS

Scn3b knockout mice exhibit abnormal ventricular electrophysiological properties

(2009) Parvez Hakim et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Extracellular Charge Adsorption Influences Intracellular Electrochemical Homeostasis in Amphibian Skeletal Muscle

(2008) Arpan R. Mehta et al.   BIOPHYSICAL JOURNAL

Animal Peptides Targeting Voltage-Activated Sodium Channels

(2008) Bert Billen et al.   CURRENT PHARMACEUTICAL DESIGN

Deconstructing voltage sensor function and pharmacology in sodium channels

(2008) Frank Bosmans et al.   NATURE

Genetic Na+ channelopathies and sinus node dysfunction

(2008) Ming Lei et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Trafficking and Cellular Distribution of Voltage-Gated Sodium Channels

(2008) Fiona S. Cusdin et al.   TRAFFIC