An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations

Microscopic Origin of Gating Current Fluctuations in a Potassium Channel Voltage Sensor

(2012) J. Alfredo Freites et al.   BIOPHYSICAL JOURNAL

Molecular Dynamics Investigation of the ω-Current in the Kv1.2 Voltage Sensor Domains

(2012) Fatemeh Khalili-Araghi et al.   BIOPHYSICAL JOURNAL

Intermediate state trapping of a voltage sensor

(2012) Jérôme J. Lacroix et al.   JOURNAL OF GENERAL PHYSIOLOGY

Voltage-gated sodium channels at 60: structure, function and pathophysiology

(2012) William A. Catterall   JOURNAL OF PHYSIOLOGY-LONDON

Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel

(2012) Xu Zhang et al.   NATURE

Crystal structure of a voltage-gated sodium channel in two potentially inactivated states

(2012) Jian Payandeh et al.   NATURE

Tracking a complete voltage-sensor cycle with metal-ion bridges

(2012) U. Henrion et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples

(2012) O. F. Lange et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of Voltage Gating in Potassium Channels

(2012) M. O. Jensen et al.   SCIENCE

Improving the Accuracy of Macromolecular Structure Refinement at 7 Å Resolution

(2012) Axel T. Brunger et al.   STRUCTURE

Molecular Dynamics Simulations of Voltage-Gated Cation Channels: Insights on Voltage-Sensor Domain Function and Modulation

(2012) Lucie Delemotte et al.   Frontiers in Pharmacology

310-Helix Conformation Facilitates the Transition of a Voltage Sensor S4 Segment toward the Down State

(2011) Christine S. Schwaiger et al.   BIOPHYSICAL JOURNAL

Properties of Deactivation Gating Currents in Shaker Channels

(2011) Jérôme J. Lacroix et al.   BIOPHYSICAL JOURNAL

Improved molecular replacement by density- and energy-guided protein structure optimization

(2011) Frank DiMaio et al.   NATURE

The crystal structure of a voltage-gated sodium channel

(2011) Jian Payandeh et al.   NATURE

In Search of a Consensus Model of the Resting State of a Voltage-Sensing Domain

(2011) Ernesto Vargas et al.   NEURON

Gating charge interactions with the S1 segment during activation of a Na+ channel voltage sensor

(2011) P. G. DeCaen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for gating charge movement in the voltage sensor of a sodium channel

(2011) V. Yarov-Yarovoy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intermediate states of the Kv1.2 voltage sensor from atomistic molecular dynamics simulations

(2011) L. Delemotte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calculation of the Gating Charge for the Kv1.2 Voltage-Activated Potassium Channel

(2010) Fatemeh Khalili-Araghi et al.   BIOPHYSICAL JOURNAL

Effect of Sensor Domain Mutations on the Properties of Voltage-Gated Ion Channels: Molecular Dynamics Studies of the Potassium Channel Kv1.2

(2010) Lucie Delemotte et al.   BIOPHYSICAL JOURNAL

310helices in channels and other membrane proteins

(2010) Ricardo Simão Vieira-Pires et al.   JOURNAL OF GENERAL PHYSIOLOGY

Principles of conduction and hydrophobic gating in K+ channels

(2010) M. O. Jensen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coupling of S4 Helix Translocation and S6 Gating Analyzed by Molecular-Dynamics Simulations of Mutated Kv Channels

(2009) Manami Nishizawa et al.   BIOPHYSICAL JOURNAL

Initial Response of the Potassium Channel Voltage Sensor to a Transmembrane Potential

(2009) Werner Treptow et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

From the gating charge response to pore domain movement: Initial motions of Kv1.2 dynamics under physiological voltage changes

(2009) Elizabeth J. Denning et al.   MOLECULAR MEMBRANE BIOLOGY

Sequential formation of ion pairs during activation of a sodium channel voltage sensor

(2009) Paul G. DeCaen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational Changes and Slow Dynamics through Microsecond Polarized Atomistic Molecular Simulation of an Integral Kv1.2 Ion Channel

(2009) Pär Bjelkmar et al.   PLoS Computational Biology

Molecular Dynamics Simulation of Kv Channel Voltage Sensor Helix in a Lipid Membrane with Applied Electric Field

(2008) Manami Nishizawa et al.   BIOPHYSICAL JOURNAL

Structure of the transmembrane regions of a bacterial cyclic nucleotide-regulated channel

(2008) G. M. Clayton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disulfide locking a sodium channel voltage sensor reveals ion pair formation during activation

(2008) P. G. DeCaen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

S4-based voltage sensors have three major conformations

(2008) C. A. Villalba-Galea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Flexible Fitting of Atomic Structures into Electron Microscopy Maps Using Molecular Dynamics

(2008) Leonardo G. Trabuco et al.   STRUCTURE