Current and future directions in the treatment and prevention of drug-induced liver injury: a systematic review

Use of apixaban after development of suspected rivaroxaban-induced hepatic steatosis; a case report

(2015) Emily J. Anastasia et al.   BLOOD COAGULATION & FIBRINOLYSIS

A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury

(2015) Chote Luangchosiri et al.   BMC Complementary and Alternative Medicine

Drug reaction with eosinophilia and systemic symptoms/drug-induced hypersensitivity syndrome: clinical features of 27 patients

(2015) J. Avancini et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Under-reporting and Poor Adherence to Monitoring Guidelines for Severe Cases of Isoniazid Hepatotoxicity

(2015) Paul H. Hayashi et al.   Clinical Gastroenterology and Hepatology

The Art and Science of Diagnosing and Managing Drug-induced Liver Injury in 2015 and Beyond

(2015) James H. Lewis   Clinical Gastroenterology and Hepatology

Safety and Tolerability of Agomelatine: Focus on Hepatotoxicity

(2015) Maximilian Gahr et al.   CURRENT DRUG METABOLISM

Clinical Pattern of Tolvaptan-Associated Liver Injury in Subjects with Autosomal Dominant Polycystic Kidney Disease: Analysis of Clinical Trials Database

(2015) Paul B. Watkins et al.   DRUG SAFETY

Discrepancies in Liver Disease Labeling in the Package Inserts of Commonly Prescribed Medications

(2015) Einar S. Bjornsson et al.   GASTROENTEROLOGY

Features and Outcomes of 899 Patients With Drug-Induced Liver Injury: The DILIN Prospective Study

(2015) Naga Chalasani et al.   GASTROENTEROLOGY

Circulating Kidney Injury Molecule 1 Predicts Prognosis and Poor Outcome in Patients With Acetaminophen-Induced Liver Injury

(2015) Daniel J. Antoine et al.   HEPATOLOGY

Ipilimumab-induced toxicities and the gastroenterologist

(2015) Robert Cheng et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Chelation in metal intoxication—Principles and paradigms

(2015) Jan Aaseth et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Chronic liver injury induced by drugs: a systematic review

(2015) Jonathan G. Stine et al.   LIVER INTERNATIONAL

Pharmacogenetic testing in idiosyncratic drug-induced liver injury: current role in clinical practice

(2015) Guruprasad P. Aithal   LIVER INTERNATIONAL

Potential of extracellular microRNAs as biomarkers of acetaminophen toxicity in children

(2015) Xi Yang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Efficacy and safety of acetylcysteine in “non-acetaminophen” acute liver failure: A meta-analysis of prospective clinical trials

(2015) Jinhua Hu et al.   Clinics and Research in Hepatology and Gastroenterology

Drug-Induced Hepatitis and Lupus during Infliximab Treatment for Psoriasis: Case Report and Literature Review

(2015) Yves Poulin et al.   JOURNAL OF CUTANEOUS MEDICINE AND SURGERY

ACG Clinical Guideline: The Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury

(2014) Naga P Chalasani et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Practical management of sunitinib toxicities in the treatment of pancreatic neuroendocrine tumors

(2014) Juan W. Valle et al.   CANCER TREATMENT REVIEWS

Impact of reducing the threshold for acetylcysteine treatment in acute paracetamol poisoning: The recent United Kingdom experience

(2014) D. N. Bateman et al.   CLINICAL TOXICOLOGY

Prescribing a Statin to a Cirrhotic Patient to Reduce Hepatic Decompensation and Improve Survival: Impossible You Say?

(2014) James H. Lewis   DIGESTIVE DISEASES AND SCIENCES

Statin Use in Patients with Cirrhosis: A Retrospective Cohort Study

(2014) Sonal Kumar et al.   DIGESTIVE DISEASES AND SCIENCES

Liver Safety Assessment: Required Data Elements and Best Practices for Data Collection and Standardization in Clinical Trials

(2014) Mark I. Avigan et al.   DRUG SAFETY

Evolution of the Food and Drug Administration Approach to Liver Safety Assessment for New Drugs: Current Status and Challenges

(2014) John R. Senior   DRUG SAFETY

Causality Assessment for Suspected DILI During Clinical Phases of Drug Development

(2014) Arie Regev et al.   DRUG SAFETY

Insights in the mechanism underlying the protective effect of α-lipoic acid against acetaminophen-hepatotoxicity

(2014) Shimaa M. Elshazly et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Protective effect of Et-1 receptor antagonist bosentan on paracetamol induced acute liver toxicity in rats

(2014) Muhammed Yayla et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Formation of reactive metabolites and management of tyrosine kinase inhibitor-induced hepatotoxicity: a literature review

(2014) Yi Ling Teo et al.   Expert Opinion on Drug Metabolism & Toxicology

Improved Prediction of the Need for Liver Transplantation in Patients With Drug-Induced Liver Injury?

(2014) Hans L. Tillmann et al.   GASTROENTEROLOGY

Spectrum of statin hepatotoxicity: Experience of the drug-induced liver injury network

(2014) Mark W. Russo et al.   HEPATOLOGY

Assessment of patients who presented to the emergency department with mushroom poisoning

(2014) S Colak et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Folic Acid and Folinic Acid for Reducing Side Effects in Patients Receiving Methotrexate for Rheumatoid Arthritis

(2014) B. Shea et al.   JOURNAL OF RHEUMATOLOGY

Elevated miR-122 serum levels are an independent marker of liver injury in inflammatory diseases

(2014) Christoph Roderburg et al.   LIVER INTERNATIONAL

The role of intestinal microbiota in murine models of acetaminophen-induced hepatotoxicity

(2014) Lucia A Possamai et al.   LIVER INTERNATIONAL

Exosome-mediated delivery of functionally active miRNA-155 inhibitor to macrophages

(2014) Fatemeh Momen-Heravi et al.   Nanomedicine-Nanotechnology Biology and Medicine

Future of pharmacogenetics-based therapy for tuberculosis

(2014) Tomoshige Matsumoto et al.   PHARMACOGENOMICS

Genetic Basis of Drug-Induced Liver Injury: Present and Future

(2014) Thomas Urban et al.   SEMINARS IN LIVER DISEASE

Review article: prescribing medications in patients with cirrhosis - a practical guide

(2013) J. H. Lewis et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Association of sustained high plasma trough concentration of voriconazole with the incidence of hepatotoxicity

(2013) Yosuke Suzuki et al.   CLINICA CHIMICA ACTA

A Point-of-Care Paper-based Fingerstick Transaminase Test: Toward Low-cost “Lab-on-a-Chip” Technology for the Developing World

(2013) Nira R. Pollock et al.   Clinical Gastroenterology and Hepatology

Managing the Risk of Drug-Induced Liver Injury

(2013) P B Watkins   CLINICAL PHARMACOLOGY & THERAPEUTICS

Identification of patients at risk of anaphylactoid reactions to N-acetylcysteine in the treatment of paracetamol overdose

(2013) Lars E. Schmidt   CLINICAL TOXICOLOGY

Drug-induced Acute Liver Failure

(2013) William M. Lee   Clinics in Liver Disease

Hepatotoxicity of Antibiotics

(2013) Jonathan G. Stine et al.   Clinics in Liver Disease

Mechanisms of Drug-induced Liver Injury

(2013) Liyun Yuan et al.   Clinics in Liver Disease

Acetaminophen-related Hepatotoxicity

(2013) Chalermrat Bunchorntavakul et al.   Clinics in Liver Disease

Improvements in Hepatic Serological Biomarkers Are Associated with Clinical Benefit of Intravenous N-Acetylcysteine in Early Stage Non-Acetaminophen Acute Liver Failure

(2013) Sundeep Singh et al.   DIGESTIVE DISEASES AND SCIENCES

Hepatotoxicity of Tyrosine Kinase Inhibitors: Clinical and Regulatory Perspectives

(2013) Rashmi R. Shah et al.   DRUG SAFETY

Mechanistic biomarkers provide early and sensitive detection of acetaminophen-induced acute liver injury at first presentation to hospital

(2013) Daniel J. Antoine et al.   HEPATOLOGY

Successful treatment of drug-induced acute liver failure with high-volume plasma exchange

(2013) Chung-Te Liu et al.   JOURNAL OF CLINICAL APHERESIS

Characteristics of liver injury in drug-induced systemic hypersensitivity reactions

(2013) Taehoon Lee et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Reduction of adverse effects from intravenous acetylcysteine treatment for paracetamol poisoning: a randomised controlled trial

(2013) D Nicholas Bateman et al.   LANCET

New biomarkers for drug-induced liver injury: are they really better? what do they diagnose?

(2013) John R. Senior   LIVER INTERNATIONAL

Comparative Efficacy and Safety of Deferoxamine, Deferiprone and Deferasirox on Severe Thalassemia: A Meta-Analysis of 16 Randomized Controlled Trials

(2013) Sujian Xia et al.   PLoS One

Long term effect of reduced pack sizes of paracetamol on poisoning deaths and liver transplant activity in England and Wales: interrupted time series analyses

(2013) K. Hawton et al.   BMJ-British Medical Journal

Serum proteomic profiling in patients with drug-induced liver injury

(2012) L. N. Bell et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Clinical Perspective: Statins and the Liver—Harmful or Helpful?

(2012) James H. Lewis   DIGESTIVE DISEASES AND SCIENCES

A case of acute valproic acid poisoning treated successfully with L-carnitine

(2012) Esther Papaseit et al.   European Journal of Emergency Medicine

Latest advances in predicting DILI in human subjects: focus on biomarkers

(2012) Maiyen Tran Hawkins et al.   Expert Opinion on Drug Metabolism & Toxicology

Statins Are Associated With a Reduced Risk of Hepatocellular Cancer: A Systematic Review and Meta-analysis

(2012) Siddharth Singh et al.   GASTROENTEROLOGY

Intravenous N-acetylcysteine in pediatric patients with nonacetaminophen acute liver failure: A placebo-controlled clinical trial

(2012) Robert H. Squires et al.   HEPATOLOGY

Extracorporeal albumin dialysis with the molecular adsorbent recirculating system in acute-on-chronic liver failure: The RELIEF trial

(2012) Rafael Bañares et al.   HEPATOLOGY

LiverTox: A website on drug-induced liver injury

(2012) Jay H. Hoofnagle et al.   HEPATOLOGY

Management of Immune-Related Adverse Events and Kinetics of Response With Ipilimumab

(2012) Jeffrey S. Weber et al.   JOURNAL OF CLINICAL ONCOLOGY

CYP2E1,GSTM1andGSTT1genetic polymorphisms and susceptibility to antituberculosis drug-induced hepatotoxicity: a nested case-control study

(2012) S.-W. Tang et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Outcome and determinants of mortality in 269 patients with combination anti-tuberculosis drug-induced liver injury

(2012) Harshad Devarbhavi et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Successful Translation of Pharmacogenetics into the Clinic

(2012) Elizabeth Phillips et al.   Molecular Diagnosis & Therapy

Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs

(2012) Thomas J. Urban et al.   Pharmacogenetics and Genomics

Gene Expression in Liver Injury Caused by Long-term Exposure to Titanium Dioxide Nanoparticles in Mice

(2012) Yaling Cui et al.   TOXICOLOGICAL SCIENCES

Leflunomide increases the risk of silent liver fibrosis in patients with rheumatoid arthritis receiving methotrexate

(2012) Sang-Won Lee et al.   ARTHRITIS RESEARCH & THERAPY

Developing Consumer-Centered, Nonprescription Drug Labeling

(2011) Jennifer P. King et al.   AMERICAN JOURNAL OF PREVENTIVE MEDICINE

Impact of different pack sizes of paracetamol in the United Kingdom and Ireland on intentional overdoses: a comparative study

(2011) Keith Hawton et al.   BMC PUBLIC HEALTH

Indications for single-dose activated charcoal administration in acute overdose

(2011) Geoffrey K. Isbister et al.   Current Opinion in Critical Care

Steroid and Ursodesoxycholic Acid Combination Therapy in Severe Drug-Induced Liver Injury

(2011) Alexander Wree et al.   DIGESTION

Drug-Induced Autoimmune-Like Hepatitis

(2011) Albert J. Czaja   DIGESTIVE DISEASES AND SCIENCES

Genetic association studies in drug-induced liver injury

(2011) Ann K. Daly et al.   DRUG METABOLISM REVIEWS

Acute Liver Failure: Current Practice and Recent Advances

(2011) Vinay Sundaram et al.   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Circulating microRNAs as potential markers of human drug-induced liver injury

(2011) Philip J. Starkey Lewis et al.   HEPATOLOGY

Causality assessment methods in drug induced liver injury: Strengths and weaknesses

(2011) Miren García-Cortés et al.   JOURNAL OF HEPATOLOGY

Nanotechnology for therapy and imaging of liver diseases

(2011) L. Harivardhan Reddy et al.   JOURNAL OF HEPATOLOGY

Approach to mushroom intoxication and treatment: Can we decrease mortality?

(2011) Emel Ahishali et al.   Clinics and Research in Hepatology and Gastroenterology

Chelation in Metal Intoxication

(2011) Swaran J.S. Flora et al.   International Journal of Environmental Research and Public Health

Imatinib and Panax Ginseng: A Potential Interaction Resulting in Liver Toxicity

(2010) Naveen Bilgi et al.   ANNALS OF PHARMACOTHERAPY

Important Elements for the Diagnosis of Drug-Induced Liver Injury

(2010) Vijay K. Agarwal et al.   Clinical Gastroenterology and Hepatology

Challenges in Reintroducing Tuberculosis Medications after Hepatotoxicity

(2010) Jussi Saukkonen   CLINICAL INFECTIOUS DISEASES

Safety of 3 Different Reintroduction Regimens of Antituberculosis Drugs after Development of Antituberculosis Treatment–Induced Hepatotoxicity

(2010) Surendra K. Sharma et al.   CLINICAL INFECTIOUS DISEASES

A multicenter comparison of the safety of oral versus intravenous acetylcysteine for treatment of acetaminophen overdose

(2010)   CLINICAL TOXICOLOGY

Protective effect of N-acetylcysteine on antituberculosis drug-induced hepatotoxicity

(2010) Shadi Baniasadi et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Causality assessment in drug-induced liver injury using a structured expert opinion process: Comparison to the Roussel-Uclaf causality assessment method

(2010) Don C. Rockey et al.   HEPATOLOGY

Drug-induced acute liver failure: Results of a U.S. multicenter, prospective study

(2010) Adrian Reuben et al.   HEPATOLOGY

Drug-induced autoimmune hepatitis: Clinical characteristics and prognosis

(2010) Einar Björnsson et al.   HEPATOLOGY

Unrecognized acetaminophen toxicity as a cause of indeterminate acute liver failure

(2010) Niraj Khandelwal et al.   HEPATOLOGY

Infliximab-related hepatitis: discussion of a case and review of the literature

(2010) Stefano Mancini et al.   Internal and Emergency Medicine

Hepatotoxic effects of therapies for tuberculosis

(2010) Bahaa E. Senousy et al.   Nature Reviews Gastroenterology & Hepatology

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Removal of Opioid/Acetaminophen Combination Prescription Pain Medications: Assessing the Evidence for Hepatotoxicity and Consequences of Removal of These Medications

(2010) Edward Michna et al.   PAIN MEDICINE

Milk thistle in liver diseases: past, present, future

(2010) Ludovico Abenavoli et al.   PHYTOTHERAPY RESEARCH

The evaluation of drug rechallenge: The casopitant Phase III program

(2010) Christine M. Hunt et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

FDA proposals to limit the hepatotoxicity of paracetamol (acetaminophen): are they reasonable?

(2010) Garry G. Graham et al.   INFLAMMOPHARMACOLOGY

An Acute Hepatitis Resembling Autoimmune Hepatitis Occurring During Imatinib Therapy in a Gastrointestinal Stromal Tumor Patient

(2009) Sandra Aliberti et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

Oral Iron Chelators

(2009) Maria Domenica Cappellini et al.   Annual Review of Medicine

Lower incidence of anaphylactoid reactions to N-acetylcysteine in patients with high acetaminophen concentrations after overdose

(2009) W. Stephen Waring et al.   CLINICAL TOXICOLOGY

Adverse reactions associated with acetylcysteine

(2009) E.A. Sandilands et al.   CLINICAL TOXICOLOGY

Use of Over-the-Counter Analgesics in Patients with Chronic Liver Disease

(2009) Simona Rossi et al.   DRUG SAFETY

Rechallenge in drug-induced liver injury: the attractive hazard

(2009) Raúl J Andrade et al.   Expert Opinion On Drug Safety

Intravenous N-Acetylcysteine Improves Transplant-Free Survival in Early Stage Non-Acetaminophen Acute Liver Failure

(2009) William M. Lee et al.   GASTROENTEROLOGY

Successful Treatment of Leflunomide-Induced Acute Pneumonitis With Cholestyramine Wash-Out Therapy

(2009) S P.Y. Wong et al.   JCR-JOURNAL OF CLINICAL RHEUMATOLOGY

Adalimumab-induced Autoimmune Hepatitis

(2009) Tomer Adar et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Outcome of liver transplantation for drug-induced acute liver failure in the United States: Analysis of the united network for organ sharing database

(2009) Ayse L. Mindikoglu et al.   LIVER TRANSPLANTATION

Drug-induced liver injury following positive drug rechallenge

(2009) Julie I. Papay et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Review article: the use of potentially hepatotoxic drugs in patients with liver disease

(2008) N. K. GUPTA et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Telithromycin-associated hepatotoxicity: Clinical spectrum and causality assessment of 42 cases

(2008) Allen D. Brinker et al.   HEPATOLOGY