Distinct signaling mechanisms regulate migration in unconfined versus confined spaces

Dimensional Control of Cancer Cell Migration

(2013) Konstantinos Konstantopoulos et al.   BIOPHYSICAL JOURNAL

Mesothelin Binding to CA125/MUC16 Promotes Pancreatic Cancer Cell Motility and Invasion via MMP-7 Activation

(2013) Shih-Hsun Chen et al.   Scientific Reports

Endothelial cells undergo morphological, biomechanical, and dynamic changes in response to tumor necrosis factor-α

(2012) Kimberly M. Stroka et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Physical confinement alters tumor cell adhesion and migration phenotypes

(2012) Eric M. Balzer et al.   FASEB JOURNAL

Selectin-mediated adhesion in shear flow using micropatterned substrates: multiple-bond interactions govern the critical length for cell binding

(2012) ZiQiu Tong et al.   Integrative Biology

Cell migration: Fibroblasts find a new way to get ahead: Figure 1.

(2012) Michael Sixt   JOURNAL OF CELL BIOLOGY

Nonpolarized signaling reveals two distinct modes of 3D cell migration

(2012) Ryan J. Petrie et al.   JOURNAL OF CELL BIOLOGY

Finding the weakest link – exploring integrin-mediated mechanical molecular pathways

(2012) Pere Roca-Cusachs et al.   JOURNAL OF CELL SCIENCE

United we stand – integrating the actin cytoskeleton and cell–matrix adhesions in cellular mechanotransduction

(2012) Ulrich S. Schwarz et al.   JOURNAL OF CELL SCIENCE

Chemotaxis of Cell Populations through Confined Spaces at Single-Cell Resolution

(2012) ZiQiu Tong et al.   PLoS One

Independent regulation of tumor cell migration by matrix stiffness and confinement

(2012) A. Pathak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endothelial cell substrate stiffness influences neutrophil transmigration via myosin light chain kinase-dependent cell contraction

(2011) K. M. Stroka et al.   BLOOD

Cancer Invasion and the Microenvironment: Plasticity and Reciprocity

(2011) Peter Friedl et al.   CELL

Myosin IIA/IIB restrict adhesive and protrusive signaling to generate front–back polarity in migrating cells

(2011) Miguel Vicente-Manzanares et al.   JOURNAL OF CELL BIOLOGY

Association between  4 integrin cytoplasmic tail and non-muscle myosin IIA regulates cell migration

(2011) L. A. R. Rosado et al.   JOURNAL OF CELL SCIENCE

Rho protein crosstalk: another social network?

(2011) Christophe Guilluy et al.   TRENDS IN CELL BIOLOGY

A Small Molecule That Inhibits the Interaction of Paxillin and α4 Integrin Inhibits Accumulation of Mononuclear Leukocytes at a Site of Inflammation

(2010) Christiane Kummer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation

(2010) Ana M. Pasapera et al.   JOURNAL OF CELL BIOLOGY

Confinement-optimized three-dimensional T cell amoeboid motility is modulated via myosin IIA–regulated adhesions

(2010) Jordan Jacobelli et al.   NATURE IMMUNOLOGY

Substrate Topography Induces a Crossover from 2D to 3D Behavior in Fibroblast Migration

(2009) Marion Ghibaudo et al.   BIOPHYSICAL JOURNAL

Mechanosensing through Cooperative Interactions between Myosin II and the Actin Crosslinker Cortexillin I

(2009) Yixin Ren et al.   CURRENT BIOLOGY

One-dimensional topography underlies three-dimensional fibrillar cell migration

(2009) Andrew D. Doyle et al.   JOURNAL OF CELL BIOLOGY

Collagen-based cell migration models in vitro and in vivo

(2009) Katarina Wolf et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

α4β1-Integrin regulates directionally persistent cell migration in response to shear flow stimulation

(2008) Dustin A. Dikeman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement

(2008) Victoria Sanz-Moreno et al.   CELL

Coordination of Rho and Rac GTPase Function via p190B RhoGAP

(2008) Rodrigo I. Bustos et al.   CURRENT BIOLOGY

Dynamic imaging of cancer growth and invasion: a modified skin-fold chamber model

(2008) Stephanie Alexander et al.   HISTOCHEMISTRY AND CELL BIOLOGY