DOCK8 deficiency

The Wiskott-Aldrich Syndrome: The Actin Cytoskeleton and Immune Cell Function

(2013) Michael P. Blundell et al.   DISEASE MARKERS

Genetic, Clinical, and Laboratory Markers for DOCK8 Immunodeficiency Syndrome

(2013) Jeremiah C. Davis et al.   DISEASE MARKERS

Clinical Manifestations of Hyper IgE Syndromes

(2013) Alexandra F. Freeman et al.   DISEASE MARKERS

CXCL12/CXCR4-Axis Dysfunctions: Markers of the Rare Immunodeficiency Disorder WHIM Syndrome

(2013) Françoise Bachelerie   DISEASE MARKERS

Deficient T Cell Receptor Excision Circles (TRECs) in autosomal recessive hyper IgE syndrome caused by DOCK8 mutation: Implications for pathogenesis and potential detection by newborn screening

(2011) Majed Dasouki et al.   CLINICAL IMMUNOLOGY

DOCK8 is essential for T-cell survival and the maintenance of CD8+ T-cell memory

(2011) Teresa Lambe et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Successful allogeneic hematopoietic stem cell transplantation for DOCK8 deficiency

(2011) Vincent Barlogis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Coronary Artery Abnormalities in Hyper-IgE Syndrome

(2011) Alexandra F. Freeman et al.   JOURNAL OF CLINICAL IMMUNOLOGY

DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice

(2011) Katrina L. Randall et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Accounting for genetic heterogeneity in homozygosity mapping: application to Mendelian susceptibility to mycobacterial disease

(2011) A. V. Grant et al.   JOURNAL OF MEDICAL GENETICS

Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5

(2011) Xiang-Ping Yang et al.   NATURE IMMUNOLOGY

Chronic Mucocutaneous Candidiasis in Humans with Inborn Errors of Interleukin-17 Immunity

(2011) A. Puel et al.   SCIENCE

Curative treatment of autosomal-recessive hyper-IgE syndrome by hematopoietic cell transplantation

(2010) S A Gatz et al.   BONE MARROW TRANSPLANTATION

Dedicator of cytokinesis 8 (DOCK8) deficiency

(2010) Helen C Su   Current Opinion in Allergy and Clinical Immunology

Successful engraftment of donor marrow after allogeneic hematopoietic cell transplantation in autosomal-recessive hyper-IgE syndrome caused by dedicator of cytokinesis 8 deficiency

(2010) Douglas R. McDonald et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Diagnostic approach to the hyper-IgE syndromes: Immunologic and clinical key findings to differentiate hyper-IgE syndromes from atopic dermatitis

(2010) Lena F. Schimke et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mutations in STAT3 and diagnostic guidelines for hyper-IgE syndrome

(2010) Cristina Woellner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation

(2010) Kazuhito Gotoh et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Successful Long-Term Correction of Autosomal Recessive Hyper-IgE Syndrome due to DOCK8 Deficiency by Hematopoietic Stem Cell Transplantation

(2010) T. C. Bittner et al.   KLINISCHE PADIATRIE

A review on the vascular features of the hyperimmunoglobulin E syndrome

(2009) H. Yavuz et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Defects along the TH17 differentiation pathway underlie genetically distinct forms of the hyper IgE syndrome

(2009) Shadi Al Khatib et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Large deletions and point mutations involving the dedicator of cytokinesis 8 (DOCK8) in the autosomal-recessive form of hyper-IgE syndrome

(2009) Karin R. Engelhardt et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Molecular explanation for the contradiction between systemic Th17 defect and localized bacterial infection in hyper-IgE syndrome

(2009) Yoshiyuki Minegishi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production

(2009) Katrina L Randall et al.   NATURE IMMUNOLOGY

Combined Immunodeficiency Associated withDOCK8Mutations

(2009) Qian Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Primary immune deficiencies with aberrant IgE production

(2008) Esra Ozcan et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Novel signal transducer and activator of transcription 3 (STAT3) mutations, reduced TH17 cell numbers, and variably defective STAT3 phosphorylation in hyper-IgE syndrome

(2008) Ellen D. Renner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Deficiency of Th17 cells in hyper IgE syndrome due to mutations inSTAT3

(2008) Cindy S. Ma et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mutations inSTAT3andIL12RB1impair the development of human IL-17–producing T cells

(2008) Ludovic de Beaucoudrey et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genomic changes in progression of low-grade gliomas

(2008) Ahmed Idbaih et al.   JOURNAL OF NEURO-ONCOLOGY

Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

(2008) Joshua D. Milner et al.   NATURE