Blockade of Tim-3 signaling restores the virus-specific CD8+T-cell response in patients with chronic hepatitis B
Published 2012 View Full Article
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Title
Blockade of Tim-3 signaling restores the virus-specific CD8+T-cell response in patients with chronic hepatitis B
Authors
Keywords
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Journal
EUROPEAN JOURNAL OF IMMUNOLOGY
Volume 42, Issue 5, Pages 1180-1191
Publisher
Wiley
Online
2012-04-27
DOI
10.1002/eji.201141852
References
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Note: Only part of the references are listed.- Tim-3 expression on peripheral T cell subsets correlates with disease progression in hepatitis B infection
- (2011) Wei Wu et al. Virology Journal
- Blockade of Tim-3 Pathway Ameliorates Interferon-γ Production from Hepatic CD8+ T Cells in a Mouse Model of Hepatitis B Virus Infection
- (2010) Ying Ju et al. Cellular & Molecular Immunology
- HCV-specific T cells in HCV/HIV co-infection show elevated frequencies of dual Tim-3/PD-1 expression that correlate with liver disease progression
- (2010) Bahareh Vali et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The immunoregulatory role of CD244 in chronic hepatitis B infection and its inhibitory potential on virus-specific CD8+ T-cell function
- (2010) Bijan Raziorrouh et al. HEPATOLOGY
- Hepatitis B e-antigen Persistency is Associated with the Properties of HBV-Specific CD8 T Cells in CHB Patients
- (2010) Guoping Peng et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Pathogenesis of hepatitis B virus infection
- (2010) F.V. Chisari et al. PATHOLOGIE BIOLOGIE
- Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection
- (2010) H.-T. Jin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The diversity of costimulatory and inhibitory receptor pathways and the regulation of antiviral T cell responses
- (2009) Alison Crawford et al. CURRENT OPINION IN IMMUNOLOGY
- Antiviral Intrahepatic T-Cell Responses Can Be Restored by Blocking Programmed Death-1 Pathway in Chronic Hepatitis B
- (2009) Paola Fisicaro et al. GASTROENTEROLOGY
- Chronic hepatitis B: Update 2009
- (2009) Anna S. F. Lok et al. HEPATOLOGY
- Circulating Th17 cells frequency is associated with the disease progression in HBV infected patients
- (2009) Wei Wu et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Dynamic decrease in PD-1 expression correlates with HBV-specific memory CD8 T-cell development in acute self-limited hepatitis B patients
- (2009) Zheng Zhang et al. JOURNAL OF HEPATOLOGY
- Negative Immune Regulator Tim-3 Is Overexpressed on T Cells in Hepatitis C Virus Infection and Its Blockade Rescues Dysfunctional CD4+ and CD8+ T Cells
- (2009) L. Golden-Mason et al. JOURNAL OF VIROLOGY
- PD-1 and Its Ligands in Tolerance and Immunity
- (2008) Mary E. Keir et al. Annual Review of Immunology
- Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection
- (2008) R. Brad Jones et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Hepatitis B Virus Infection
- (2008) Jules L. Dienstag NEW ENGLAND JOURNAL OF MEDICINE
- PD-1 upregulation is associated with HBV-specific T cell dysfunction in chronic hepatitis B patients
- (2007) Guoping Peng et al. MOLECULAR IMMUNOLOGY
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