Augmented generation of protein fragments during wakefulness as the molecular cause of sleep: a hypothesis
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Title
Augmented generation of protein fragments during wakefulness as the molecular cause of sleep: a hypothesis
Authors
Keywords
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Journal
PROTEIN SCIENCE
Volume 21, Issue 11, Pages 1634-1661
Publisher
Wiley
Online
2012-08-28
DOI
10.1002/pro.2148
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Note: Only part of the references are listed.- Changes in Components of Energy Regulation in Mouse Cortex with Increases in Wakefulness
- (2017) Elena V. Nikonova et al. SLEEP
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- (2012) Takafumi Tasaki et al. Annual Review of Biochemistry
- Calcium signalling remodelling and disease
- (2012) Michael J. Berridge BIOCHEMICAL SOCIETY TRANSACTIONS
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- (2012) Julie Seibt et al. CURRENT BIOLOGY
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- (2012) Lorenzo Galluzzi et al. EMBO REPORTS
- Calpain-mediated Degradation of Myocyte Enhancer Factor 2D Contributes to Excitotoxicity by Activation of ExtrasynapticN-Methyl-d-aspartate Receptors
- (2012) Gengze Wei et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2012) L. I. Schmitt et al. JOURNAL OF NEUROSCIENCE
- Deletion of Ecto-5'-Nucleotidase (CD73) Reveals Direct Action Potential-Dependent Adenosine Release
- (2012) B. P. Klyuch et al. JOURNAL OF NEUROSCIENCE
- Calpain Cleavage of Brain Glutamic Acid Decarboxylase 65 Is Pathological and Impairs GABA Neurotransmission
- (2012) Chandana Buddhala et al. PLoS One
- Talin Contains A C-Terminal Calpain2 Cleavage Site Important In Focal Adhesion Dynamics
- (2012) Neil Bate et al. PLoS One
- Global kinetic analysis of proteolysis via quantitative targeted proteomics
- (2012) N. J. Agard et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Critical role for calcium mobilization in activation of the NLRP3 inflammasome
- (2012) T. Murakami et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments
- (2012) K. I. Piatkov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Protein N-terminal acetyltransferases: when the start matters
- (2012) Kristian K. Starheim et al. TRENDS IN BIOCHEMICAL SCIENCES
- Calcium Signaling in Dendritic Spines
- (2012) M. J. Higley et al. Cold Spring Harbor Perspectives in Biology
- The Core Apoptotic Executioner Proteins CED-3 and CED-4 Promote Initiation of Neuronal Regeneration in Caenorhabditis elegans
- (2012) Berangere Pinan-Lucarre et al. PLOS BIOLOGY
- Caspase Substrates and Cellular Remodeling
- (2011) Emily D. Crawford et al. Annual Review of Biochemistry
- The N-end rule pathway: From recognition by N-recognins, to destruction by AAA+proteases
- (2011) D.A. Dougan et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Calpains — An elaborate proteolytic system
- (2011) Yasuko Ono et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Tear Me Down
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- Hippocampal ripples and memory consolidation
- (2011) Gabrielle Girardeau et al. CURRENT OPINION IN NEUROBIOLOGY
- The Role of Adenosine in the Regulation of Sleep
- (2011) Zhi-Li Huang et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- RIG-I RNA Helicase Activation of IRF3 Transcription Factor Is Negatively Regulated by Caspase-8-Mediated Cleavage of the RIP1 Protein
- (2011) Akhil Rajput et al. IMMUNITY
- Brain-specific interleukin-1 receptor accessory protein in sleep regulation
- (2011) Ping Taishi et al. JOURNAL OF APPLIED PHYSIOLOGY
- Cohesin loading and sliding
- (2011) M. T. Ocampo-Hafalla et al. JOURNAL OF CELL SCIENCE
- Proteolytically cleaved MLL subunits are susceptible to distinct degradation pathways
- (2011) A. Yokoyama et al. JOURNAL OF CELL SCIENCE
- Astrocyte-Derived Adenosine and A1 Receptor Activity Contribute to Sleep Loss-Induced Deficits in Hippocampal Synaptic Plasticity and Memory in Mice
- (2011) C. Florian et al. JOURNAL OF NEUROSCIENCE
- Calpain-1 Cleaves Rad21 To Promote Sister Chromatid Separation
- (2011) A. K. Panigrahi et al. MOLECULAR AND CELLULAR BIOLOGY
- The ClpS Adaptor Mediates Staged Delivery of N-End Rule Substrates to the AAA+ ClpAP Protease
- (2011) Giselle Román-Hernández et al. MOLECULAR CELL
- BRCA1 Is Required for Postreplication Repair after UV-Induced DNA Damage
- (2011) Shailja Pathania et al. MOLECULAR CELL
- Local sleep in awake rats
- (2011) Vladyslav V. Vyazovskiy et al. NATURE
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- (2011) Kim Nasmyth NATURE CELL BIOLOGY
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- Calmodulin as a direct detector of Ca2+ signals
- (2011) Guido C Faas et al. NATURE NEUROSCIENCE
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- (2011) Nadezhda Tikhmyanova et al. PLoS One
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- (2009) J. W. Heck et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2008) Matthew T. Scharf et al. PROGRESS IN NEUROBIOLOGY
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- (2007) E. Dargelos et al. BIOCHIMIE
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