Tear Me Down

Proteasome functional insufficiency activates the calcineurin–NFAT pathway in cardiomyocytes and promotes maladaptive remodelling of stressed mouse hearts

(2010) Mingxin Tang et al.   CARDIOVASCULAR RESEARCH

Differential Regulation of Proteasome Function in Isoproterenol-Induced Cardiac Hypertrophy

(2010) Oliver Drews et al.   CIRCULATION RESEARCH

Role of nuclear factor κB in cardiovascular health and disease

(2010) Kim van der Heiden et al.   CLINICAL SCIENCE

Calpains: Attractive Targets for the Development of Synthetic Inhibitors

(2010) Markus Pietsch et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Calpain inhibition attenuates intracellular changes in muscle cells in response to extracellular inflammatory stimulation

(2010) Kenkichi Nozaki et al.   EXPERIMENTAL NEUROLOGY

Increased expression of calpain and elevated activity of calcineurin in the myocardium of patients with congestive heart failure

(2010) Yang   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

In vitro degradation of bovine myofibrils is caused by μ-calpain, not caspase-31

(2010) D. A. Mohrhauser et al.   JOURNAL OF ANIMAL SCIENCE

Lack of β3 Integrin Signaling Contributes to Calpain-Mediated Myocardial Cell Loss in Pressure-Overloaded Myocardium

(2010) Geetha Suryakumar et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Calpain translocation and activation as pharmacological targets during myocardial ischemia/reperfusion

(2010) Víctor Hernando et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Muscle ring finger 1 mediates cardiac atrophy in vivo

(2009) Monte S. Willis et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Autophagy is required for preconditioning by the adenosine A1 receptor-selective agonist CCPA

(2009) Smadar Yitzhaki et al.   BASIC RESEARCH IN CARDIOLOGY

Focal adhesion kinase signaling in cardiac hypertrophy and failure

(2009) K.G. Franchini et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Orphan targets for reperfusion injury

(2009) J. Inserte et al.   CARDIOVASCULAR RESEARCH

Proteasome inhibitors and cardiac cell growth

(2009) N. Hedhli et al.   CARDIOVASCULAR RESEARCH

Over-expression of calpastatin inhibits calpain activation and attenuates myocardial dysfunction during endotoxaemia

(2009) X. Li et al.   CARDIOVASCULAR RESEARCH

Calcium, Calpains, and Cardiac Hypertrophy: A New Link

(2009) Felix M. Heidrich et al.   CIRCULATION RESEARCH

Left ventricular hypertrophy and renin-angiotensin system blockade

(2009) Brett R. Cowan et al.   CURRENT HYPERTENSION REPORTS

Chronic β-AR activation-induced calpain activation and impaired eNOS–Akt signaling mediates cardiac injury in ovariectomized female rats

(2009) Md. Shenuarin Bhuiyan et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

β3 Integrin-mediated ubiquitination activates survival signaling during myocardial hypertrophy

(2009) Rebecca K. Johnston et al.   FASEB JOURNAL

Integrins and proximal signaling mechanisms in cardiovascular disease

(2009) Hind Lal   Frontiers in Bioscience-Landmark

Tenderness – An enzymatic view

(2009) Caroline M. Kemp et al.   MEAT SCIENCE

In vivo administration of calpeptin attenuates calpain activation and cardiomyocyte loss in pressure-overloaded feline myocardium

(2008) Santhosh K. Mani et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Glycogen synthase kinase 3 (GSK3) in the heart: a point of integration in hypertrophic signalling and a therapeutic target? A critical analysis

(2008) P H Sugden et al.   BRITISH JOURNAL OF PHARMACOLOGY

Chromogranin B Regulates Calcium Signaling, Nuclear Factor κB Activity, and Brain Natriuretic Peptide Production in Cardiomyocytes

(2008) Felix M. Heidrich et al.   CIRCULATION RESEARCH

Targeting the Calpain/Calpastatin System as a New Strategy to Prevent Cardiovascular Remodeling in Angiotensin II–Induced Hypertension

(2008) Emmanuel Letavernier et al.   CIRCULATION RESEARCH

Autophagy in Load-Induced Heart Disease

(2008) Beverly A. Rothermel et al.   CIRCULATION RESEARCH

Caspases — An update

(2008) Indrajit Chowdhury et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Taurine prevents cardiomyocyte death by inhibiting NADPH oxidase-mediated calpain activation

(2008) Y LI et al.   FREE RADICAL BIOLOGY AND MEDICINE

Functional Role of HSP90 Complexes with Endothelial Nitric-oxide Synthase (eNOS) and Calpain on Nitric Oxide Generation in Endothelial Cells

(2008) Monica Averna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calpain mediates cardiac troponin degradation and contractile dysfunction in atrial fibrillation

(2008) Lei Ke et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

With great power comes great responsibility: Using mouse genetics to study cardiac hypertrophy and failure

(2008) Jeffery D. Molkentin et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Calcium-dependent proteolytic system and muscle dysfunctions: A possible role of calpains in sarcopenia

(2007) E. Dargelos et al.   BIOCHIMIE

Calpain inhibition attenuates right ventricular contractile dysfunction after acute pressure overload

(2007) Clifford R. Greyson et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY