Whole grains beyond fibre: what can metabolomics tell us about mechanisms?

Methylation and Gene Expression Responses to Ethanol Feeding and Betaine Supplementation in the Cystathionine Beta Synthase-Deficient Mouse

(2014) Valentina Medici et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Effects of whole and refined grains in a weight-loss diet on markers of metabolic syndrome in individuals with increased waist circumference: a randomized controlled-feeding trial

(2014) Kristina Harris Jackson et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Similar metabolic responses in pigs and humans to breads with different contents and compositions of dietary fibers: a metabolomics study

(2014) Kirstine L Nielsen et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Effects of insulin resistance on skeletal muscle growth and exercise capacity in type 2 diabetic mouse models

(2014) Joseph E. Ostler et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Recent findings on certain bioactive components in whole grain wheat and rye

(2014) Annica A.M. Andersson et al.   JOURNAL OF CEREAL SCIENCE

The Postprandial Plasma Rye Fingerprint Includes Benzoxazinoid-Derived Phenylacetamide Sulfates

(2014) Kati Hanhineva et al.   JOURNAL OF NUTRITION

Metabolomics Reveals Differences in Postprandial Responses to Breads and Fasting Metabolic Characteristics Associated with Postprandial Insulin Demand in Postmenopausal Women

(2014) Ali A. Moazzami et al.   JOURNAL OF NUTRITION

Disintegration of wheat aleurone structure has an impact on the bioavailability of phenolic compounds and other phytochemicals as evidenced by altered urinary metabolite profile of diet-induced obese mice

(2014) Jenna Pekkinen et al.   Nutrition & Metabolism

Variation of serum metabolites related to habitual diet: a targeted metabolomic approach in EPIC-Potsdam

(2013) A Floegel et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Cereal foods are the major source of betaine in the Western diet – Analysis of betaine and free choline in cereal foods and updated assessments of betaine intake

(2013) Alastair B. Ross et al.   FOOD CHEMISTRY

A Whole-Grain–Rich Diet Reduces Urinary Excretion of Markers of Protein Catabolism and Gut Microbiota Metabolism in Healthy Men after One Week

(2013) Alastair B. Ross et al.   JOURNAL OF NUTRITION

Hippurate: The Natural History of a Mammalian–Microbial Cometabolite

(2013) Hannah J. Lees et al.   JOURNAL OF PROTEOME RESEARCH

Multicompartmental Nontargeted LC–MS Metabolomics: Explorative Study on the Metabolic Responses of Rye Fiber versus Refined Wheat Fiber Intake in Plasma and Urine of Hypercholesterolemic Pigs

(2013) Natalja P. Nørskov et al.   JOURNAL OF PROTEOME RESEARCH

Branched chain and aromatic amino acids change acutely following two medical therapies for type 2 diabetes mellitus

(2013) Geoffrey A. Walford et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Transcriptomic and epigenetic changes in early liver steatosis associated to obesity: Effect of dietary methyl donor supplementation

(2013) Paul Cordero et al.   MOLECULAR GENETICS AND METABOLISM

Betaine supplementation causes increase in carnitine metabolites in the muscle and liver of mice fed a high-fat diet as studied by nontargeted LC-MS metabolomics approach

(2013) Jenna Pekkinen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

UPLC-QTOF/MS metabolic profiling unveils urinary changes in humans after a whole grain rye versus refined wheat bread intervention

(2013) Isabel Bondia-Pons et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

(2013) V. K. Ridaura et al.   SCIENCE

Interplay between Lipids and Branched-Chain Amino Acids in Development of Insulin Resistance

(2012) Christopher B. Newgard   Cell Metabolism

Cardiovascular Benefits of Dietary Fiber

(2012) Ambika Satija et al.   Current Atherosclerosis Reports

Metabolic Signatures of Insulin Resistance in 7,098 Young Adults

(2012) P. Wurtz et al.   DIABETES

Branched-Chain and Aromatic Amino Acids Are Predictors of Insulin Resistance in Young Adults

(2012) P. Wurtz et al.   DIABETES CARE

Whole Grain Compared with Refined Wheat Decreases the Percentage of Body Fat Following a 12-Week, Energy-Restricted Dietary Intervention in Postmenopausal Women

(2012) Mette Kristensen et al.   JOURNAL OF NUTRITION

Greater Whole-Grain Intake Is Associated with Lower Risk of Type 2 Diabetes, Cardiovascular Disease, and Weight Gain

(2012) Eva Qing Ye et al.   JOURNAL OF NUTRITION

Metabolomics reveals the metabolic shifts following an intervention with rye bread in postmenopausal women- a randomized control trial

(2012) Ali A Moazzami et al.   Nutrition Journal

Metabolomics and human nutrition

(2011) Sandy Primrose et al.   BRITISH JOURNAL OF NUTRITION

A whole-grain cereal-rich diet increases plasma betaine, and tends to decrease total and LDL-cholesterol compared with a refined-grain diet in healthy subjects

(2011) Alastair B. Ross et al.   BRITISH JOURNAL OF NUTRITION

Harnessing Metabolomics for Nutrition Research

(2011) Michael A. Zulyniak et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Nuclear Magnetic Resonance–Based Metabolomics Enable Detection of the Effects of a Whole Grain Rye and Rye Bran Diet on the Metabolic Profile of Plasma in Prostate Cancer Patients

(2011) Ali A. Moazzami et al.   JOURNAL OF NUTRITION

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

Postprandial differences in the plasma metabolome of healthy Finnish subjects after intake of a sourdough fermented endosperm rye bread versus white wheat bread

(2011) Isabel Bondia-Pons et al.   Nutrition Journal

Health benefits of cereal fibre: a review of clinical trials

(2011) Caren E. Smith et al.   NUTRITION RESEARCH REVIEWS

Whole grain rye breakfast — Sustained satiety during three weeks of regular consumption

(2011) Hanna Isaksson et al.   PHYSIOLOGY & BEHAVIOR

Whole- and refined-grain intakes are differentially associated with abdominal visceral and subcutaneous adiposity in healthy adults: the Framingham Heart Study

(2010) Nicola M McKeown et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Consumption of Wheat Aleurone-Rich Foods Increases Fasting Plasma Betaine and Modestly Decreases Fasting Homocysteine and LDL-Cholesterol in Adults

(2010) Ruth K. Price et al.   JOURNAL OF NUTRITION

Metabolomic Analysis of Plasma Metabolites That May Mediate Effects of Rye Bread on Satiety and Weight Maintenance in Postmenopausal Women

(2010) Maria Lankinen et al.   JOURNAL OF NUTRITION

Rye Whole Grain and Bran Intake Compared with Refined Wheat Decreases Urinary C-Peptide, Plasma Insulin, and Prostate Specific Antigen in Men with Prostate Cancer

(2010) Rikard Landberg et al.   JOURNAL OF NUTRITION

Effects of Dietary Fiber and Its Components on Metabolic Health

(2010) James M. Lattimer et al.   Nutrients

Factors related to colonic fermentation of nondigestible carbohydrates of a previous evening meal increase tissue glucose uptake and moderate glucose-associated inflammation

(2009) Marion G Priebe et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Quantitative aspects of the metabolism of lignans in pigs fed fibre-enriched rye and wheat bread

(2009) Helle N. Lærke et al.   BRITISH JOURNAL OF NUTRITION

Urine metabolite analysis as a function of deoxynivalenol exposure: an NMR-based metabolomics investigation

(2009) R.P. Hopton et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

NMR-based metabonomics reveals that plasma betaine increases upon intake of high-fiber rye buns in hypercholesterolemic pigs

(2009) Hanne Christine Bertram et al.   MOLECULAR NUTRITION & FOOD RESEARCH