TGF-β inhibition enhances chemotherapy action against triple-negative breast cancer

Gene Expression, Molecular Class Changes, and Pathway Analysis after Neoadjuvant Systemic Therapy for Breast Cancer

(2012) A. M. Gonzalez-Angulo et al.   CLINICAL CANCER RESEARCH

PTTG1Oncogene Promotes Tumor Malignancy via Epithelial to Mesenchymal Transition and Expansion of Cancer Stem Cell Population

(2012) Chang-Hwan Yoon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TGFβ induces the formation of tumour-initiating cells in claudinlow breast cancer

(2012) Alejandra Bruna et al.   Nature Communications

TGFβ-dependent induction of interleukin-11 and interleukin-8 involves SMAD and p38 MAPK pathways in breast tumor models with varied bone metastases potential

(2011) Janhavi Gupta et al.   CANCER BIOLOGY & THERAPY

Exploring anti-TGF-β therapies in cancer and fibrosis

(2011) Lukas J. A. C. Hawinkels et al.   GROWTH FACTORS

Anti-Transforming Growth Factor   Receptor II Antibody Has Therapeutic Efficacy against Primary Tumor Growth and Metastasis through Multieffects on Cancer, Stroma, and Immune Cells

(2010) Z. Zhong et al.   CLINICAL CANCER RESEARCH

CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts

(2010) Christophe Ginestier et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting the Transforming Growth Factor-β pathway inhibits human basal-like breast cancer metastasis

(2010) Vidya Ganapathy et al.   Molecular Cancer

Targeting breast cancer stem cells

(2010) Sean P. McDermott et al.   Molecular Oncology

Transforming growth factor-β regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM

(2010) Y Wang et al.   ONCOGENE

Breast Cancer Cell Lines Contain Functional Cancer Stem Cells with Metastatic Capacity and a Distinct Molecular Signature

(2009) Emmanuelle Charafe-Jauffret et al.   CANCER RESEARCH

ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays

(2009) Yifang Hu et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Multiple Lineages of Human Breast Cancer Stem/Progenitor Cells Identified by Profiling with Stem Cell Markers

(2009) Wendy W. Hwang-Verslues et al.   PLoS One

Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

(2009) C. J. Creighton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transforming Growth Factor-  Regulates Mammary Carcinoma Cell Survival and Interaction with the Adjacent Microenvironment

(2008) B. Bierie et al.   CANCER RESEARCH

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

TGFβ Primes Breast Tumors for Lung Metastasis Seeding through Angiopoietin-like 4

(2008) David Padua et al.   CELL

NANOG Is a Direct Target of TGFβ/Activin-Mediated SMAD Signaling in Human ESCs

(2008) Ren-He Xu et al.   Cell Stem Cell

Beyond Cytotoxic Chemotherapy for the First-Line Treatment of HER2-Negative, Hormone-Insensitive Metastatic Breast Cancer: Current Status and Future Opportunities

(2008) Alison K. Conlin et al.   Clinical Breast Cancer

Response to Neoadjuvant Therapy and Long-Term Survival in Patients With Triple-Negative Breast Cancer

(2008) Cornelia Liedtke et al.   JOURNAL OF CLINICAL ONCOLOGY

Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy

(2008) X. Li et al.   JNCI-Journal of the National Cancer Institute

Direct multiplexed measurement of gene expression with color-coded probe pairs

(2008) Gary K Geiss et al.   NATURE BIOTECHNOLOGY

Semi-mechanistic modelling of the tumour growth inhibitory effects of LY2157299, a new type I receptor TGF-β kinase antagonist, in mice

(2007) Lorea Bueno et al.   EUROPEAN JOURNAL OF CANCER