The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia

Comprehensive meta-analysis of Signal Transducers and Activators of Transcription (STAT) genomic binding patterns discerns cell-specific cis-regulatory modules

(2013) Keunsoo Kang et al.   BMC GENOMICS

JAK and STAT Signaling Molecules in Immunoregulation and Immune-Mediated Disease

(2012) John J. O'Shea et al.   IMMUNITY

Early steps of microglial activation are directly affected by neuroprotectant FK506 in both in vitro inflammation and in rat model of stroke

(2012) Malgorzata Zawadzka et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

(2012) Laurens Kruidenier et al.   NATURE

STAT1 as a novel therapeutical target in pro-atherogenic signal integration of IFNγ, TLR4 and IL-6 in vascular disease

(2011) Krzysztof Sikorski et al.   CYTOKINE & GROWTH FACTOR REVIEWS

IRF7: activation, regulation, modification and function

(2011) S Ning et al.   GENES AND IMMUNITY

p53 Interaction with JMJD3 Results in Its Nuclear Distribution during Mouse Neural Stem Cell Differentiation

(2011) Susana Solá et al.   PLoS One

Probe set filtering increases correlation between Affymetrix GeneChip and qRT-PCR expression measurements

(2010) Jakub Mieczkowski et al.   BMC BIOINFORMATICS

Mechanisms Underlying Inflammation in Neurodegeneration

(2010) Christopher K. Glass et al.   CELL

IL-6 Trans-Signaling Modulates TLR4-Dependent Inflammatory Responses via STAT3

(2010) C. J. Greenhill et al.   JOURNAL OF IMMUNOLOGY

Jmjd3 and UTX Play a Demethylase-Independent Role in Chromatin Remodeling to Regulate T-Box Family Member-Dependent Gene Expression

(2010) Sara A. Miller et al.   MOLECULAR CELL

Suppression of inflammation by a synthetic histone mimic

(2010) Edwige Nicodeme et al.   NATURE

CC and CXC chemokines are pivotal mediators of cerebral injury in ischaemic stroke

(2010) Giorgio Luciano Viviani et al.   THROMBOSIS AND HAEMOSTASIS

Jmjd3 contributes to the control of gene expression in LPS-activated macrophages

(2009) Francesca De Santa et al.   EMBO JOURNAL

The different functions of Stat5 and chromatin alteration through Stat5 proteins

(2008) Jan-Wilhelm Kornfeld   Frontiers in Bioscience-Landmark

Targeting signaling pathways with small molecules to treat autoimmune disorders

(2007) Bozena Kaminska et al.   Expert Review of Clinical Immunology