Insight into the heterogeneity of breast cancer through next-generation sequencing

Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

(2011) Philip J. Stephens et al.   CELL

Tumour evolution inferred by single-cell sequencing

(2011) Nicholas Navin et al.   NATURE

Cells of origin in cancer

(2011) Jane E. Visvader   NATURE

The genomic complexity of primary human prostate cancer

(2011) Michael F. Berger et al.   NATURE

A decade’s perspective on DNA sequencing technology

(2011) Elaine R. Mardis   NATURE

Breast Cancer Management: Opportunities and Barriers to an Individualized Approach

(2011) E. A. Perez   ONCOLOGIST

Exploring the Genomes of Cancer Cells: Progress and Promise

(2011) M. R. Stratton   SCIENCE

Combinatorial biomarker expression in breast cancer

(2010) Emad A. Rakha et al.   BREAST CANCER RESEARCH AND TREATMENT

Intra-tumour genetic heterogeneity and poor chemoradiotherapy response in cervical cancer

(2010) S L Cooke et al.   BRITISH JOURNAL OF CANCER

How Darwinian models inform therapeutic failure initiated by clonal heterogeneity in cancer medicine

(2010) M Gerlinger et al.   BRITISH JOURNAL OF CANCER

A Comprehensive Survey of Clonal Diversity Measures in Barrett's Esophagus as Biomarkers of Progression to Esophageal Adenocarcinoma

(2010) L. M. F. Merlo et al.   Cancer Prevention Research

BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells

(2010) Gemma Molyneux et al.   Cell Stem Cell

Heterogeneity for Stem Cell-Related Markers According to Tumor Subtype and Histologic Stage in Breast Cancer

(2010) S. Y. Park et al.   CLINICAL CANCER RESEARCH

A Comparison of PAM50 Intrinsic Subtyping with Immunohistochemistry and Clinical Prognostic Factors in Tamoxifen-Treated Estrogen Receptor-Positive Breast Cancer

(2010) T. O. Nielsen et al.   CLINICAL CANCER RESEARCH

Next-generation sequencing: emerging lessons on the origins of human cancer

(2010) Gerd P Pfeifer et al.   CURRENT OPINION IN ONCOLOGY

Use of cancer-specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors

(2010) David J. McBride et al.   GENES CHROMOSOMES & CANCER

The importance of platform annotation in interpreting microarray data

(2010) Mark J Dunning et al.   LANCET ONCOLOGY

The importance of gene-centring microarray data

(2010) Therese Sørlie et al.   LANCET ONCOLOGY

Clinical implementation of the intrinsic subtypes of breast cancer

(2010) Charles M Perou et al.   LANCET ONCOLOGY

Breast cancer molecular profiling with single sample predictors: a retrospective analysis

(2010) Britta Weigelt et al.   LANCET ONCOLOGY

Next Generation Sequencing of Serum Circulating Nucleic Acids from Patients with Invasive Ductal Breast Cancer Reveals Differences to Healthy and Nonmalignant Controls

(2010) J. Beck et al.   MOLECULAR CANCER RESEARCH

Tracing the tumor lineage

(2010) Nicholas E. Navin et al.   Molecular Oncology

DNA methylation patterns in luminal breast cancers differ from non-luminal subtypes and can identify relapse risk independent of other clinical variables

(2010) Sitharthan Kamalakaran et al.   Molecular Oncology

Methylation profiling with a panel of cancer related genes: Association with estrogen receptor, TP53 mutation status and expression subtypes in sporadic breast cancer

(2010) Jo Anders Rønneberg et al.   Molecular Oncology

Diverse somatic mutation patterns and pathway alterations in human cancers

(2010) Zhengyan Kan et al.   NATURE

Genome remodelling in a basal-like breast cancer metastasis and xenograft

(2010) Li Ding et al.   NATURE

International network of cancer genome projects

(2010) Thomas J. Hudson (Chairperson) et al.   NATURE

Breast cancer assessment tools and optimizing adjuvant therapy

(2010) Catherine Oakman et al.   Nature Reviews Clinical Oncology

Advances in understanding cancer genomes through second-generation sequencing

(2010) Matthew Meyerson et al.   NATURE REVIEWS GENETICS

Genomic analysis of genetic heterogeneity and evolution in high-grade serous ovarian carcinoma

(2010) S L Cooke et al.   ONCOGENE

A pathway-based classification of human breast cancer

(2010) M. L. Gatza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic Architecture Characterizes Tumor Progression Paths and Fate in Breast Cancer Patients

(2010) H. G. Russnes et al.   Science Translational Medicine

Development of Personalized Tumor Biomarkers Using Massively Parallel Sequencing

(2010) R. J. Leary et al.   Science Translational Medicine

The $1,000 genome, the $100,000 analysis?

(2010) Elaine R Mardis   Genome Medicine

Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors

(2010) Steven JM Jones et al.   GENOME BIOLOGY

Molecular classification of solid tumours: towards pathway-driven therapeutics

(2009) C Swanton et al.   BRITISH JOURNAL OF CANCER

Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics

(2009) B. T. Hennessy et al.   CANCER RESEARCH

Linking somatic genetic alterations in cancer to therapeutics

(2009) Darrin Stuart et al.   CURRENT OPINION IN CELL BIOLOGY

Inferring tumor progression from genomic heterogeneity

(2009) N. Navin et al.   GENOME RESEARCH

Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes

(2009) Joel S. Parker et al.   JOURNAL OF CLINICAL ONCOLOGY

Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

(2009) Sohrab P. Shah et al.   NATURE

Complex landscapes of somatic rearrangement in human breast cancer genomes

(2009) Philip J. Stephens et al.   NATURE

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

(2009) Elgene Lim et al.   NATURE MEDICINE

Identification of small gains and losses in single cells after whole genome amplification on tiling oligo arrays

(2009) Jochen B. Geigl et al.   NUCLEIC ACIDS RESEARCH

Biological Processes Associated with Breast Cancer Clinical Outcome Depend on the Molecular Subtypes

(2008) C. Desmedt et al.   CLINICAL CANCER RESEARCH

A sequence-level map of chromosomal breakpoints in the MCF-7 breast cancer cell line yields insights into the evolution of a cancer genome

(2008) O. A. Hampton et al.   GENOME RESEARCH

Refinement of breast cancer classification by molecular characterization of histological special types

(2008) B Weigelt et al.   JOURNAL OF PATHOLOGY

Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing

(2008) Peter J Campbell et al.   NATURE GENETICS

High-resolution array comparative genomic hybridization of single micrometastatic tumor cells

(2008) Christine Fuhrmann et al.   NUCLEIC ACIDS RESEARCH

Understanding the Molecular Basis of Histologic Grade

(2008) M. Ignatiadis et al.   PATHOBIOLOGY

Cell type-specific DNA methylation patterns in the human breast

(2008) N. Bloushtain-Qimron et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA