Dynamin2 controls Rap1 activation and integrin clustering in human T lymphocyte adhesion

Plasticity of Cell Migration In Vivo and In Silico

(2016) Veronika te Boekhorst et al.   Annual Review of Cell and Developmental Biology

The Rap1-RIAM-talin axis of integrin activation and blood cell function

(2016) F. Lagarrigue et al.   BLOOD

The kindlin family: functions, signaling properties and implications for human disease

(2016) Emanuel Rognoni et al.   JOURNAL OF CELL SCIENCE

Integrin-based therapeutics: biological basis, clinical use and new drugs

(2016) Klaus Ley et al.   NATURE REVIEWS DRUG DISCOVERY

Rap1 and its effector RIAM are required for lymphocyte trafficking

(2015) W. Su et al.   BLOOD

Loss of the Rap1 effector RIAM results in leukocyte adhesion deficiency due to impaired  2 integrin function in mice

(2015) S. Klapproth et al.   BLOOD

Regulation of integrin-mediated adhesions

(2015) Daniel V Iwamoto et al.   CURRENT OPINION IN CELL BIOLOGY

Dynamin 2-dependent endocytosis sustains T-cell receptor signaling and drives metabolic reprogramming in T lymphocytes

(2015) Tim Willinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrin activation

(2015) Mark H. Ginsberg   BMB Reports

Rap1-GTP-interacting adaptor molecule (RIAM) is dispensable for platelet integrin activation and function in mice

(2014) S. Stritt et al.   BLOOD

Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis

(2014) M. Y. Lee et al.   DEVELOPMENT

Functions of the FAK family kinases in T cells: beyond actin cytoskeletal rearrangement

(2014) Nicole M. Chapman et al.   IMMUNOLOGIC RESEARCH

Dynamin 2–dependent endocytosis is required for sustained S1PR1 signaling

(2014) Tim Willinger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Rap1b Regulates B Cell Development, Homing, and T Cell-Dependent Humoral Immunity

(2014) H. Chu et al.   JOURNAL OF IMMUNOLOGY

A novel pathway of rapid TLR-triggered activation of integrin-dependent leukocyte adhesion that requires Rap1 GTPase

(2014) Kyoung-Jin Chung et al.   MOLECULAR BIOLOGY OF THE CELL

Synthesis of Dynole 34-2, Dynole 2-24 and Dyngo 4a for investigating dynamin GTPase

(2014) Mark J Robertson et al.   Nature Protocols

Dynamin 2 Potentiates Invasive Migration of Pancreatic Tumor Cells through Stabilization of the Rac1 GEF Vav1

(2013) Gina L. Razidlo et al.   DEVELOPMENTAL CELL

The Spontaneously Adhesive Leukocyte Function-associated Antigen-1 (LFA-1) Integrin in Effector T Cells Mediates Rapid Actin- and Calmodulin-dependent Adhesion Strengthening to Ligand under Shear Flow

(2013) Hwee San Lek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complete integrin headpiece opening in eight steps

(2013) Jieqing Zhu et al.   JOURNAL OF CELL BIOLOGY

Dynamin triple knockout cells reveal off target effects of commonly used dynamin inhibitors

(2013) R. J. Park et al.   JOURNAL OF CELL SCIENCE

Essential Function of Dynamin in the Invasive Properties and Actin Architecture of v-Src Induced Podosomes/Invadosomes

(2013) Olivier Destaing et al.   PLoS One

Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation

(2012) C. T. Lefort et al.   BLOOD

Chemokine-triggered leukocyte arrest: force-regulated bi-directional integrin activation in quantal adhesive contacts

(2012) Ronen Alon et al.   CURRENT OPINION IN CELL BIOLOGY

CCR7-mediated LFA-1 functions in T cells are regulated by 2 independent ADAP/SKAP55 modules

(2011) S. Kliche et al.   BLOOD

CD81 is essential for the formation of membrane protrusions and regulates Rac1-activation in adhesion-dependent immune cell migration

(2011) T. Quast et al.   BLOOD

Integrin inside-out signaling and the immunological synapse

(2011) Timothy A Springer et al.   CURRENT OPINION IN CELL BIOLOGY

A direct interaction between the large GTPase dynamin-2 and FAK regulates focal adhesion dynamics in response to active Src

(2011) Yu Wang et al.   MOLECULAR BIOLOGY OF THE CELL

Direct dynamin–actin interactions regulate the actin cytoskeleton

(2010) Changkyu Gu et al.   EMBO JOURNAL

T Cell Receptor “Inside-Out” Pathway via Signaling Module SKAP1-RapL Regulates T Cell Motility and Interactions in Lymph Nodes

(2010) Monika Raab et al.   IMMUNITY

The final steps of integrin activation: the end game

(2010) Sanford J. Shattil et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of integrin activity and signalling

(2009) Carl G. Gahmberg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Rap1 controls lymphocyte adhesion cascade and interstitial migration within lymph nodes in RAPL-dependent and -independent manners

(2009) Y. Ebisuno et al.   BLOOD

Control of cell adhesion dynamics by Rap1 signaling

(2009) Benjamin Boettner et al.   CURRENT OPINION IN CELL BIOLOGY

Mechanical modes of ‘amoeboid’ cell migration

(2009) Tim Lämmermann et al.   CURRENT OPINION IN CELL BIOLOGY

Myosin-IIA and ICAM-1 Regulate the Interchange between Two Distinct Modes of T Cell Migration

(2009) J. Jacobelli et al.   JOURNAL OF IMMUNOLOGY

Inhibition of Dynamin Mediated Endocytosis by theDynoles—Synthesis and Functional Activity of a Family of Indoles

(2009) Timothy A. Hill et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dynamin Reduces Pyk2 Y402 Phosphorylation and Src Binding in Osteoclasts

(2009) A. Bruzzaniti et al.   MOLECULAR AND CELLULAR BIOLOGY

The Tail of Integrins, Talin, and Kindlins

(2009) M. Moser et al.   SCIENCE

Role of the small GTPase Rap1 for integrin activity regulation in endothelial cells and angiogenesis

(2008) G. Carmona et al.   BLOOD

RIAM Activates Integrins by Linking Talin to Ras GTPase Membrane-targeting Sequences

(2008) Ho-Sup Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms and consequences of agonist-induced talin recruitment to platelet integrin αIIbβ3

(2008) Naohide Watanabe et al.   JOURNAL OF CELL BIOLOGY

The WAVE2 complex regulates T cell receptor signaling to integrins via Abl- and CrkL–C3G-mediated activation of Rap1

(2008) Jeffrey C. Nolz et al.   JOURNAL OF CELL BIOLOGY

Pyk2 mediates endothelin-1 signaling via p130Cas/BCAR3 cascade and regulates human glomerular mesangial cell adhesion and spreading

(2008) Victoriya A. Rufanova et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Rapid leukocyte migration by integrin-independent flowing and squeezing

(2008) Tim Lämmermann et al.   NATURE