Synthesis of Dynole 34-2, Dynole 2-24 and Dyngo 4a for investigating dynamin GTPase

Pyrimidyn Compounds: Dual-Action Small Molecule Pyrimidine-Based Dynamin Inhibitors

(2013) Andrew B. McGeachie et al.   ACS Chemical Biology

A Nibbling Mechanism for Clathrin-mediated Retrieval of Secretory Granule Membrane after Exocytosis

(2013) Mary A. Bittner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamin triple knockout cells reveal off target effects of commonly used dynamin inhibitors

(2013) R. J. Park et al.   JOURNAL OF CELL SCIENCE

Target validation using chemical probes

(2013) Mark E Bunnage et al.   Nature Chemical Biology

Dynamin Inhibitors Impair Endocytosis and Mitogenic Signaling of PDGF

(2013) Łukasz Sadowski et al.   TRAFFIC

Flotillins Regulate Membrane Mobility of the Dopamine Transporter but Are Not Required for Its Protein Kinase C Dependent Endocytosis

(2013) Tatiana Sorkina et al.   TRAFFIC

Building a Better Dynasore: The Dyngo Compounds Potently Inhibit Dynamin and Endocytosis

(2013) Adam McCluskey et al.   TRAFFIC

Membrane Shape at the Edge of the Dynamin Helix Sets Location and Duration of the Fission Reaction

(2012) Sandrine Morlot et al.   CELL

Dynamin Regulates Specific Membrane Fusion Events Necessary for Acrosomal Exocytosis in Mouse Spermatozoa

(2012) Andrew T. Reid et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Development of Second-Generation Indole-Based Dynamin GTPase Inhibitors

(2012) Christopher P. Gordon et al.   JOURNAL OF MEDICINAL CHEMISTRY

Analysis of synaptic vesicle endocytosis in synaptosomes by high-content screening

(2012) James A Daniel et al.   Nature Protocols

Dynamin, a membrane-remodelling GTPase

(2012) Shawn M. Ferguson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Clathrin-Mediated Endocytic Proteins are Involved in Regulating Mitotic Progression and Completion

(2012) Charlotte M. Smith et al.   TRAFFIC

Targeting membrane trafficking in infection prophylaxis: dynamin inhibitors

(2012) Callista B. Harper et al.   TRENDS IN CELL BIOLOGY

The Rhodadyns, a New Class of Small Molecule Inhibitors of Dynamin GTPase Activity

(2012) Mark J. Robertson et al.   ACS Medicinal Chemistry Letters

Dynamics of Intracellular Clathrin/AP1- and Clathrin/AP3-Containing Carriers

(2012) Comert Kural et al.   Cell Reports

Dynamin: Functional Design of a Membrane Fission Catalyst

(2011) Sandra L. Schmid et al.   Annual Review of Cell and Developmental Biology

Intracellular curvature-generating proteins in cell-to-cell fusion

(2011) Jean-Philippe Richard et al.   BIOCHEMICAL JOURNAL

A Pseudoatomic Model of the Dynamin Polymer Identifies a Hydrolysis-Dependent Powerstroke

(2011) Joshua S. Chappie et al.   CELL

Dynamin Inhibition Blocks Botulinum Neurotoxin Type A Endocytosis in Neurons and Delays Botulism

(2011) Callista B. Harper et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Dynamin by Dynole 34-2 Induces Cell Death following Cytokinesis Failure in Cancer Cells

(2011) M. Chircop et al.   MOLECULAR CANCER THERAPEUTICS

Crystal structure of nucleotide-free dynamin

(2011) Katja Faelber et al.   NATURE

The crystal structure of dynamin

(2011) Marijn G. J. Ford et al.   NATURE

A direct role for Met endocytosis in tumorigenesis

(2011) Carine Joffre et al.   NATURE CELL BIOLOGY

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

(2011) Harvey T. McMahon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ThePthaladyns: GTP Competitive Inhibitors of Dynamin I and II GTPase Derived from Virtual Screening

(2010) Luke R. Odell et al.   JOURNAL OF MEDICINAL CHEMISTRY

Iminochromene Inhibitors of Dynamins I and II GTPase Activity and Endocytosis

(2010) Timothy A. Hill et al.   JOURNAL OF MEDICINAL CHEMISTRY

G domain dimerization controls dynamin's assembly-stimulated GTPase activity

(2010) Joshua S. Chappie et al.   NATURE

Structural basis of oligomerization in the stalk region of dynamin-like MxA

(2010) Song Gao et al.   NATURE

Suppression of dynamin GTPase activity by sertraline leads to inhibition of dynamin-dependent endocytosis

(2009) Kiyofumi Takahashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Azido and Diazarinyl Analogues of Bis-Tyrphostin as Asymmetrical Inhibitors of Dynamin GTPase

(2009) Luke R. Odell et al.   ChemMedChem

Inhibition of Dynamin Mediated Endocytosis by theDynoles—Synthesis and Functional Activity of a Family of Indoles

(2009) Timothy A. Hill et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synaptic vesicle endocytosis: fast and slow modes of membrane retrieval

(2008) Stephen M. Smith et al.   TRENDS IN NEUROSCIENCES

From Spanish fly to room-temperature ionic liquids (RTILs): synthesis, thermal stability and inhibition of dynamin 1 GTPase by a novel class of RTILs

(2007) Jie Zhang et al.   NEW JOURNAL OF CHEMISTRY