Functions of the FAK family kinases in T cells: beyond actin cytoskeletal rearrangement

CD28 and CD3 have complementary roles in T-cell traction forces

(2014) Keenan T. Bashour et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Focal Adhesion Kinase Negatively Regulates Lck Function Downstream of the T Cell Antigen Receptor

(2013) N. M. Chapman et al.   JOURNAL OF IMMUNOLOGY

Disrupting the Scaffold to Improve Focal Adhesion Kinase-Targeted Cancer Therapeutics

(2013) W. G. Cance et al.   Science Signaling

Induction and stability of the anergic phenotype in T cells

(2013) Rut Valdor et al.   SEMINARS IN IMMUNOLOGY

Mechanosensing in T Lymphocyte Activation

(2012) Edward Judokusumo et al.   BIOPHYSICAL JOURNAL

Pyk2 cytonuclear localization: mechanisms and regulation by serine dephosphorylation

(2012) Camille Faure et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Small molecule inhibitors of the Pyk2 and FAK kinases modulate chemoattractant-induced migration, adhesion and Akt activation in follicular and marginal zone B cells

(2012) Kathy W.K. Tse et al.   CELLULAR IMMUNOLOGY

F-actin polymerization and retrograde flow drive sustained PLCγ1 signaling during T cell activation

(2012) Alexander Babich et al.   JOURNAL OF CELL BIOLOGY

Non-Catalytic Functions of Pyk2 and Fyn Regulate Late Stage Adhesion in Human T Cells

(2012) Nicole M. Chapman et al.   PLoS One

The adaptor protein LAT serves as an integration node for signaling pathways that drive T cell activation

(2012) Rebekah R. Bartelt et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Microtubule-organizing center polarity and the immunological synapse: protein kinase C and beyond

(2012) Morgan Huse   Frontiers in Immunology

CD44-mediated elongated T cell spreading requires Pyk2 activation by Src family kinases, extracellular calcium, phospholipase C and phosphatidylinositol-3 kinase

(2011) Nelson K.Y. Wong et al.   CELLULAR SIGNALLING

Hypophosphorylated and inactive Pyk2 associates with paxillin at the microtubule organizing center in hematopoietic cells

(2011) Joëlle St-Pierre et al.   CELLULAR SIGNALLING

Integrin inside-out signaling and the immunological synapse

(2011) Timothy A Springer et al.   CURRENT OPINION IN CELL BIOLOGY

Transcriptional control of T-cell development

(2011) T. Naito et al.   INTERNATIONAL IMMUNOLOGY

Feedback Circuits Monitor and Adjust Basal Lck-Dependent Events in T Cell Receptor Signaling

(2011) J. R. Schoenborn et al.   Science Signaling

Constitutively Active Lck Kinase in T Cells Drives Antigen Receptor Signal Transduction

(2010) Konstantina Nika et al.   IMMUNITY

The Phosphatase PTP-PEST Promotes Secondary T Cell Responses by Dephosphorylating the Protein Tyrosine Kinase Pyk2

(2010) Dominique Davidson et al.   IMMUNITY

Shaping the T-cell repertoire: a matter of life and death

(2010) G Jan Wiegers et al.   IMMUNOLOGY AND CELL BIOLOGY

Regulation of the Tyrosine Kinase Pyk2 by Calcium Is through Production of Reactive Oxygen Species in Cytotoxic T Lymphocytes

(2010) Tara L. Lysechko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular functions of FAK kinases: insight into molecular mechanisms and novel functions

(2010) M. D. Schaller   JOURNAL OF CELL SCIENCE

T cell receptor activation leads to two distinct phases of Pyk2 activation and actin cytoskeletal rearrangement in human T cells

(2010) Michaela Collins et al.   MOLECULAR IMMUNOLOGY

The FERM domain: organizing the structure and function of FAK

(2010) Margaret C. Frame et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Proline-rich tyrosine kinase-2 is critical for CD8 T-cell short-lived effector fate

(2010) S. Beinke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mediation of T-Cell Activation by Actin Meshworks

(2010) P. Beemiller et al.   Cold Spring Harbor Perspectives in Biology

T Cell Activation

(2009) Jennifer E. Smith-Garvin et al.   Annual Review of Immunology

The T cell receptor-mediated phosphorylation of Pyk2 tyrosines 402 and 580 occurs via a distinct mechanism than other receptor systems

(2009) Michaela Collins et al.   JOURNAL OF LEUKOCYTE BIOLOGY

An arrestin-dependent multi-kinase signaling complex mediates MIP-1β/CCL4 signaling and chemotaxis of primary human macrophages

(2009) Ricky Cheung et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A Synaptic Basis for Paracrine Interleukin-2 Signaling during Homotypic T Cell Interaction

(2008) Catherine A. Sabatos et al.   IMMUNITY

Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK

(2008) Sara M. Weis et al.   JOURNAL OF CELL BIOLOGY

Structural Basis for the Interaction between Focal Adhesion Kinase and CD4

(2007) Marie-Line Garron et al.   JOURNAL OF MOLECULAR BIOLOGY