Dynamin 2-dependent endocytosis sustains T-cell receptor signaling and drives metabolic reprogramming in T lymphocytes
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Title
Dynamin 2-dependent endocytosis sustains T-cell receptor signaling and drives metabolic reprogramming in T lymphocytes
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 112, Issue 14, Pages 4423-4428
Publisher
Proceedings of the National Academy of Sciences
Online
2015-03-24
DOI
10.1073/pnas.1504279112
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Note: Only part of the references are listed.- Dynamin 2–dependent endocytosis is required for sustained S1PR1 signaling
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- Serine-threonine kinases in TCR signaling
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- Dynamin triple knockout cells reveal off target effects of commonly used dynamin inhibitors
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- Receptor signals come in waves
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- Distinct TCR signaling pathways drive proliferation and cytokine production in T cells
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- Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation
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- Metabolic reprogramming and metabolic dependency in T cells
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- PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+T cells
- (2012) David K. Finlay et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Dynamin, a membrane-remodelling GTPase
- (2012) Shawn M. Ferguson et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Canonical autophagy dependent on the class III phosphoinositide-3 kinase Vps34 is required for naive T-cell homeostasis
- (2012) T. Willinger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation
- (2011) Ruoning Wang et al. IMMUNITY
- Protein Kinase B Controls Transcriptional Programs that Direct Cytotoxic T Cell Fate but Is Dispensable for T Cell Metabolism
- (2011) Andrew N. Macintyre et al. IMMUNITY
- Endocytosed BCRs sequentially regulate MAPK and Akt signaling pathways from intracellular compartments
- (2011) Akanksha Chaturvedi et al. NATURE IMMUNOLOGY
- Methods in Mammalian Autophagy Research
- (2010) Noboru Mizushima et al. CELL
- Imaging T-cell receptor activation reveals accumulation of tyrosine-phosphorylated CD3 in the endosomal compartment
- (2010) I. A. Yudushkin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Endocytosis and signalling: intertwining molecular networks
- (2009) Alexander Sorkin et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
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