Chiral phosphine-catalyzed tunable cycloaddition reactions of allenoates with benzofuranone-derived olefins for a highly regio-, diastereo- and enantioselective synthesis of spiro-benzofuranones

Phosphahelicenes in Asymmetric Organocatalysis: [3+2] Cyclizations of γ-Substituted Allenes and Electron-Poor Olefins

(2015) Maxime Gicquel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective synthesis of 3-fluoro-3-allyl-oxindoles via phosphine-catalyzed asymmetric γ-addition of 3-fluoro-oxindoles to 2,3-butadienoates

(2015) Tianli Wang et al.   CHEMICAL COMMUNICATIONS

Use of a New Spirophosphine To Achieve Catalytic Enantioselective [4 + 1] Annulations of Amines with Allenes To Generate Dihydropyrroles

(2015) Søren Kramer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phosphine-Catalyzed Enantioselective Intramolecular [3+2] Annulations To Generate Fused Ring Systems

(2015) Sarah Yunmi Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly enantioselective construction of tertiary thioethers and alcohols via phosphine-catalyzed asymmetric γ-addition reactions of 5H-thiazol-4-ones and 5H-oxazol-4-ones: scope and mechanistic understandings

(2015) Tianli Wang et al.   Chemical Science

Phosphine-Catalyzed Enantioselective γ-Addition of 3-Substituted Oxindoles to 2,3-Butadienoates and 2-Butynoates: Use of Prochiral Nucleophiles

(2014) Tianli Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of Spiropyrazolones through Phosphine-Catalyzed [4+1] Annulation

(2014) Xiaoyu Han et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phosphine catalysis of allenes with electrophiles

(2014) Zhiming Wang et al.   CHEMICAL SOCIETY REVIEWS

A Computational Study: Reactivity Difference between Phosphine- and Amine-Catalyzed Cycloadditions of Allenoates and Enones

(2014) Gou-Tao Huang et al.   JOURNAL OF ORGANIC CHEMISTRY

Hydroxyproline-Derived Pseudoenantiomeric [2.2.1] Bicyclic Phosphines: Asymmetric Synthesis of (+)- and (−)-Pyrrolines

(2014) Christopher E. Henry et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Enantioselective Synthesis of 3,4-Dihydropyrans through a Phosphine-Catalyzed [4+2] Annulation of Allenones and β,γ-Unsaturated α-Keto Esters

(2014) Weijun Yao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A computational study of the activation of allenoates by Lewis bases and the reactivity of intermediate adducts

(2014) Gou-Tao Huang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Advances in nucleophilic phosphine catalysis of alkenes, allenes, alkynes, and MBHADs

(2013) Yi Chiao Fan et al.   CHEMICAL COMMUNICATIONS

Synthesis of Optically Enriched Spirocyclic Benzofuran-2-ones by Bifunctional Thiourea-Base Catalyzed Double-Michael Addition of Benzofuran-2-ones to Dienones

(2013) Xin Li et al.   Chemistry-An Asian Journal

Phosphine-Catalyzed Synthesis of 3,3-Spirocyclopenteneoxindoles from γ-Substituted Allenoates: Systematic Studies and Targeted Applications

(2013) Catherine Gomez et al.   JOURNAL OF ORGANIC CHEMISTRY

Pd(II)-Catalyzed Enantioselective C–H Activation/C–O Bond Formation: Synthesis of Chiral Benzofuranones

(2013) Xiu-Fen Cheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The origin of enantioselectivity in the l-threonine-derived phosphine–sulfonamide catalyzed aza-Morita–Baylis–Hillman reaction: effects of the intramolecular hydrogen bonding

(2013) Richmond Lee et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Phosphine-containing Lewis base catalyzed cyclization of benzofuranone type electron-deficient alkenes with allenoates: a facile synthesis of spirocyclic benzofuranones

(2013) Xin Li et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of 3,3′-Spirocyclic Oxindoles via Phosphine Catalyzed [4 + 2] Cyclizations

(2013) Maxime Gicquel et al.   ORGANIC LETTERS

Heterocyclic Spiranes and Dispiranes via Enantioselective Phosphine-Catalyzed [3+2] Annulations

(2012) Deepti Duvvuru et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantioselective Synthesis of Highly Functionalized Phosphonate-Substituted Pyrans or Dihydropyrans Through Asymmetric [4+2] Cycloaddition of β,γ-Unsaturated α-Ketophosphonates with Allenic Esters

(2012) Cheng-Kui Pei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Phosphine Catalyzed Asymmetric Michael Addition of Oxindoles

(2012) Fangrui Zhong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Construction of adjacent spiro-quaternary and tertiary stereocenters through phosphine-catalyzed asymmetric [3+2] annulation of allenoates with alkylidene azlactones

(2012) De Wang et al.   CHEMICAL COMMUNICATIONS

Asymmetric Michael Addition Reactions between 3-Substituted Benzofuran-2(3H)-ones and 1,1-Bis(phenylsulfonyl)ethylene Catalyzed by Bifunctional Catalysts Containing Tertiary Amine and Thiourea Groups

(2012) Xin Li et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Exploiting the Modularity of Ion-Paired Chiral Ligands for Palladium-Catalyzed Enantioselective Allylation of Benzofuran-2(3H)-ones

(2012) Kohsuke Ohmatsu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Regio-, Diastereo-, and Enantioselective 1,6- and 1,8-Additions of Azlactones to Di- and Trienyl N-Acylpyrroles

(2012) Daisuke Uraguchi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Enantioselective Regiodivergent Allylic Alkylations of MBH Carbonates with Phthalides

(2012) Fangrui Zhong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Construction of Functionalized Bicyclic Imides via [3 + 2] Annulation of MBH Carbonates Catalyzed by Dipeptide-Based Phosphines

(2012) Fangrui Zhong et al.   ORGANIC LETTERS

Highly enantioselective [4 + 2] annulations catalyzed by amino acid-based phosphines: Synthesis of functionalized cyclohexenes and 3-spirocyclohexene-2-oxindoles

(2012) Fangrui Zhong et al.   Chemical Science

Allenoate-derived 1,5-, 1,7-, and 1,9-zwitterions as highly versatile coupling-partners for phosphine-triggered cycloaddition reactions

(2012) Wei Meng et al.   Chemical Science

Enantioselective Intermolecular Rauhut-Currier Reaction of Electron-Deficient Allenes with Maleimides

(2011) Qian-Yi Zhao et al.   ADVANCED SYNTHESIS & CATALYSIS

Palladium-Catalyzed Diastereo- and Enantioselective Synthesis of Substituted Cyclopentanes through a Dynamic Kinetic Asymmetric Formal [3+2]-Cycloaddition of Vinyl Cyclopropanes and Alkylidene Azlactones

(2011) Barry M. Trost et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Base-Free Electrophilic Amination of Benzofuran-2(3H)-ones: Catalysis by Binol-Derived P-Spiro Quaternary Phosphonium Salts

(2011) Chuan-Le Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Versatile Enantioselective [3+2] Cyclization between Imines and Allenoates Catalyzed by Dipeptide-Based Phosphines

(2011) Xiaoyu Han et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Enantioselective [3+2] Annulation of Morita-Baylis-Hillman Adducts Mediated by L-Threonine-Derived Phosphines: Synthesis of 3-Spirocyclopentene-2-oxindoles having Two Contiguous Quaternary Centers

(2011) Fangrui Zhong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dioxindole in Asymmetric Catalytic Synthesis: Routes to Enantioenriched 3-Substituted 3-Hydroxyoxindoles and the Preparation of Maremycin A

(2011) Giulia Bergonzini et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Development of asymmetric phosphine-promoted annulations of allenes with electron-deficient olefins and imines

(2011) Qian-Yi Zhao et al.   CHEMICAL COMMUNICATIONS

Asymmetric [3+2] annulation of allenes with maleimides catalyzed by dipeptide-derived phosphines: facile creation of functionalized bicyclic cyclopentenes containing two tertiary stereogenic centers

(2011) Qianyi Zhao et al.   CHEMICAL COMMUNICATIONS

Chiral Biscinchona Alkaloid Promoted Asymmetric Allylic Alkylation of 3-Substituted Benzofuran-2(3H)-ones with Morita–Baylis–Hillman Carbonates

(2011) Cong Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Application of a New Chiral Phosphepine to the Catalytic Asymmetric Synthesis of Highly Functionalized Cyclopentenes That Bear an Array of Heteroatom-Substituted Quaternary Stereocenters

(2011) Yuji Fujiwara et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective [3 + 2] Cycloaddition of Allenes to Acrylates Catalyzed by Dipeptide-Derived Phosphines: Facile Creation of Functionalized Cyclopentenes Containing Quaternary Stereogenic Centers

(2011) Xiaoyu Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phosphine-Catalyzed Annulations of Azomethine Imines: Allene-Dependent [3 + 2], [3 + 3], [4 + 3], and [3 + 2 + 3] Pathways

(2011) Risong Na et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Morita–Baylis–Hillman reaction promoted by l-threonine-derived phosphine–thiourea catalysts

(2011) Xiaoyu Han et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

l-Threonine-Derived Novel Bifunctional Phosphine−Sulfonamide Catalyst-Promoted Enantioselective Aza-Morita−Baylis−Hillman Reaction

(2011) Fangrui Zhong et al.   ORGANIC LETTERS

Phosphine- and Nitrogen-Containing Lewis Base Catalyzed Highly Regioselective and Geometric Selective Cyclization of Isatin Derived Electron-Deficient Alkenes with Ethyl 2,3-Butadienoate

(2011) Xiu-Chun Zhang et al.   ORGANIC LETTERS

Multifunctional Chiral Phosphine Organocatalysts in Catalytic Asymmetric Morita−Baylis−Hillman and Related Reactions

(2010) Yin Wei et al.   ACCOUNTS OF CHEMICAL RESEARCH

Highly Enantioselective Michael Addition Reactions of 3-Substituted Benzofuran-2(3H)-ones to Chalcones Catalyzed by a Chiral Alkyl-Substituted Thiourea

(2010) Xin Li et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric [3+2] Cycloadditions of Allenoates and Dual Activated Olefins Catalyzed by Simple Bifunctional N-Acyl Aminophosphines

(2010) Hua Xiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic synthesis of spiro compounds via a cascade Michael–Michael-aldol reaction

(2010) Xavier Companyó et al.   CHEMICAL COMMUNICATIONS

Multiple approaches to enantiopure spirocyclic benzofuranones using organocatalytic cascade reactions

(2010) Carlo Cassani et al.   CHEMICAL COMMUNICATIONS

Organocatalytic enantioselective desymmetrization of cyclic enonesviaphosphine promoted [3+2] annulations

(2010) Nathalie Pinto et al.   CHEMICAL COMMUNICATIONS

Phosphine-catalyzed highly diastereoselective [3+2] cyclization of isatin derived electron-deficient alkenes with α-allenic esters

(2010) Xiu-Chun Zhang et al.   CHEMICAL COMMUNICATIONS

An Organocatalytic [3+2] Cyclisation Strategy for the Highly Enantioselective Synthesis of Spirooxindoles

(2010) Arnaud Voituriez et al.   CHEMISTRY-A EUROPEAN JOURNAL

Chiral Amine Thiourea-Promoted Enantioselective Michael Addition Reactions of 3-Substituted Benzofuran-2(3H)-ones to Maleimides

(2010) Xin Li et al.   JOURNAL OF ORGANIC CHEMISTRY

Total Synthesis and Biological Evaluation of the Resveratrol-Derived Polyphenol Natural Products Hopeanol and Hopeahainol A

(2010) K. C. Nicolaou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Studies on the asymmetric, phosphine-promoted [3+2] annulations of allenic esters with 2-aryl-1,1-dicyanoalkenes

(2010) Marie Schuler et al.   TETRAHEDRON-ASYMMETRY

Highly enantio-, regio- and diastereo-selective one-pot [2 + 3]-cycloaddition reaction via isomerization of 3-butynoates to allenoates,

(2010) Magesh Sampath et al.   Chemical Science

Synthesis of Chiral 2-Phospha[3]ferrocenophanes and their Behaviour as Organocatalysts in [3+2] Cyclization Reactions

(2009) Arnaud Voituriez et al.   ADVANCED SYNTHESIS & CATALYSIS

Phosphine-Catalyzed Enantioselective Synthesis of Oxygen Heterocycles

(2009) Ying Kit Chung et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Silicon as a directing group in the phosphine-catalyzed [2 + 3]-cycloaddition of aryl allenones with electron-deficient olefins

(2009) Magesh Sampath et al.   CHEMICAL COMMUNICATIONS

Enantioselective catalysis and complexity generation from allenoates

(2009) Bryan J. Cowen et al.   CHEMICAL SOCIETY REVIEWS

Expanding the Scope of Enantioselective FerroPHANE-Promoted [3+2] Annulations with α,β-Unsaturated Ketones

(2009) Nathalie Pinto et al.   CHEMISTRY-A EUROPEAN JOURNAL

Phosphane-Catalyzed [3+2] Annulation of Allenoates with Aldehydes: A Simple and Efficient Synthesis of 2-Alkylidenetetrahydrofurans

(2009) Silong Xu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Phosphine Organocatalysis

(2009) Angela Marinetti et al.   SYNLETT

Chiral Diphosphine and Monodentate Phosphorus Ligands on a Spiro Scaffold for Transition-Metal-Catalyzed Asymmetric Reactions

(2008) Jian-Hua Xie et al.   ACCOUNTS OF CHEMICAL RESEARCH

The oxa-Michael reaction: from recent developments to applications in natural product synthesis

(2008) Carl F. Nising et al.   CHEMICAL SOCIETY REVIEWS

Phosphine-triggered synthesis of functionalized cyclic compounds

(2008) Long-Wu Ye et al.   CHEMICAL SOCIETY REVIEWS

Mechanism, Regioselectivity, and the Kinetics of Phosphine-Catalyzed [3+2] Cycloaddition Reactions of Allenoates and Electron-Deficient Alkenes

(2008) Yong Liang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Use of Allenylphosphonates as New Substrates for Phosphane-Catalyzed [3+2] and [4+2] Annulations

(2008) Armen Panossian et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Totally Regio- and Stereoselective Behavior of Mono- and Diactivated Cyclic Alkenes in the Lu Reaction: Synthesis of Enantiopure Functionalized Cyclopentanes

(2008) José L. García Ruano et al.   JOURNAL OF ORGANIC CHEMISTRY

2-Phospha[3]ferrocenophanes with Planar Chirality: Synthesis and Use in Enantioselective Organocatalytic [3 + 2] Cyclizations

(2008) Arnaud Voituriez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cooperative, Highly Enantioselective Phosphinothiourea Catalysis of Imine−Allene [3 + 2] Cycloadditions

(2008) Yuan-Qing Fang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Alcohol-Assisted Phosphine Catalysis:  One-Step Syntheses of Dihydropyrones from Aldehydes and Allenoates

(2008) Gardner S. Creech et al.   ORGANIC LETTERS