Asymmetric Synthesis of Spiropyrazolones through Phosphine-Catalyzed [4+1] Annulation

Phosphine-Catalyzed Enantioselective γ-Addition of 3-Substituted Oxindoles to 2,3-Butadienoates and 2-Butynoates: Use of Prochiral Nucleophiles

(2014) Tianli Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Amine-Promoted Asymmetric (4+2) Annulations for the Enantioselective Synthesis of Tetrahydropyridines: A Traceless and Recoverable Auxiliary Strategy

(2013) Pengfei Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Advances in nucleophilic phosphine catalysis of alkenes, allenes, alkynes, and MBHADs

(2013) Yi Chiao Fan et al.   CHEMICAL COMMUNICATIONS

Arylazanylpyrazolone Derivatives as Inhibitors of Mutant Superoxide Dismutase 1 Dependent Protein Aggregation for the Treatment of Amyotrophic Lateral Sclerosis

(2013) Yinan Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

The origin of enantioselectivity in the l-threonine-derived phosphine–sulfonamide catalyzed aza-Morita–Baylis–Hillman reaction: effects of the intramolecular hydrogen bonding

(2013) Richmond Lee et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Highly Z-Selective Asymmetric Conjugate Addition of Alkynones with Pyrazol-5-ones Promoted by N,N′-Dioxide-Metal Complexes

(2012) Zhen Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Phosphine Catalyzed Asymmetric Michael Addition of Oxindoles

(2012) Fangrui Zhong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric [4+2] Annulation Initiated by an Aza-Rauhut-Currier Reaction: Facile Entry to Highly Functionalized Tetrahydropyridines

(2012) Zugui Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phosphine-catalyzed asymmetric [4+1] annulation of Morita–Baylis–Hillman carbonates with dicyano-2-methylenebut-3-enoates

(2012) Xiao-nan Zhang et al.   CHEMICAL COMMUNICATIONS

Highly Diastereo- and Enantioselective Organocatalytic One-Pot Sequential 1,4-Addition/Dearomative-Fluorination Transformation

(2012) Feng Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Highly Enantioselective Synthesis of Spiro[cyclohexanone-oxindoles] and Spiro[cyclohexanone-pyrazolones] by Asymmetric Cascade [5+1] Double Michael Reactions

(2012) Bin Wu et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Highly Enantioselective Regiodivergent Allylic Alkylations of MBH Carbonates with Phthalides

(2012) Fangrui Zhong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An organocatalytic asymmetric double Michael cascade reaction of unsaturated ketones and unsaturated pyrazolones: highly efficient synthesis of spiropyrazolone derivatives

(2012) Jinyan Liang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Asymmetric Construction of Functionalized Bicyclic Imides via [3 + 2] Annulation of MBH Carbonates Catalyzed by Dipeptide-Based Phosphines

(2012) Fangrui Zhong et al.   ORGANIC LETTERS

Highly enantioselective [4 + 2] annulations catalyzed by amino acid-based phosphines: Synthesis of functionalized cyclohexenes and 3-spirocyclohexene-2-oxindoles

(2012) Fangrui Zhong et al.   Chemical Science

Allenoate-derived 1,5-, 1,7-, and 1,9-zwitterions as highly versatile coupling-partners for phosphine-triggered cycloaddition reactions

(2012) Wei Meng et al.   Chemical Science

Highly Enantioselective Michael Addition of Pyrazolin-5-ones Catalyzed by Chiral Metal/N,N′-Dioxide Complexes: Metal-Directed Switch in Enantioselectivity

(2011) Zhen Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Versatile Enantioselective [3+2] Cyclization between Imines and Allenoates Catalyzed by Dipeptide-Based Phosphines

(2011) Xiaoyu Han et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Enantioselective [3+2] Annulation of Morita-Baylis-Hillman Adducts Mediated by L-Threonine-Derived Phosphines: Synthesis of 3-Spirocyclopentene-2-oxindoles having Two Contiguous Quaternary Centers

(2011) Fangrui Zhong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Amine-Catalyzed [4+2] Annulations of Allenoates and Oxo-dienes: An Asymmetric Synthesis of Dihydropyrans

(2011) Xiaojun Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Development of asymmetric phosphine-promoted annulations of allenes with electron-deficient olefins and imines

(2011) Qian-Yi Zhao et al.   CHEMICAL COMMUNICATIONS

Asymmetric [3+2] annulation of allenes with maleimides catalyzed by dipeptide-derived phosphines: facile creation of functionalized bicyclic cyclopentenes containing two tertiary stereogenic centers

(2011) Qianyi Zhao et al.   CHEMICAL COMMUNICATIONS

Asymmetric Organocatalytic Cyclization and Cycloaddition Reactions

(2011) Albert Moyano et al.   CHEMICAL REVIEWS

Highly Stereoselective Synthesis of Spiropyrazolones

(2011) Andrea-Nekane R. Alba et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Phosphine-Catalyzed [4 + 1] Annulation between α,β-Unsaturated Imines and Allylic Carbonates: Synthesis of 2-Pyrrolines

(2011) Junjun Tian et al.   JOURNAL OF ORGANIC CHEMISTRY

Core-Structure-Motivated Design of a Phosphine-Catalyzed [3 + 2] Cycloaddition Reaction: Enantioselective Syntheses of Spirocyclopenteneoxindoles

(2011) Bin Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Application of a New Chiral Phosphepine to the Catalytic Asymmetric Synthesis of Highly Functionalized Cyclopentenes That Bear an Array of Heteroatom-Substituted Quaternary Stereocenters

(2011) Yuji Fujiwara et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective [3 + 2] Cycloaddition of Allenes to Acrylates Catalyzed by Dipeptide-Derived Phosphines: Facile Creation of Functionalized Cyclopentenes Containing Quaternary Stereogenic Centers

(2011) Xiaoyu Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phosphine-Catalyzed Annulations of Azomethine Imines: Allene-Dependent [3 + 2], [3 + 3], [4 + 3], and [3 + 2 + 3] Pathways

(2011) Risong Na et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly enantioselective cascade synthesis of spiropyrazolones

(2011) Alex Zea et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective Morita–Baylis–Hillman reaction promoted by l-threonine-derived phosphine–thiourea catalysts

(2011) Xiaoyu Han et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Asymmetric α-Amination of 4-Substituted Pyrazolones Catalyzed by a Chiral Gd(OTf)3/N,N′-Dioxide Complex: Highly Enantioselective Synthesis of 4-Amino-5-pyrazolone Derivatives

(2011) Zhigang Yang et al.   ORGANIC LETTERS

l-Threonine-Derived Novel Bifunctional Phosphine−Sulfonamide Catalyst-Promoted Enantioselective Aza-Morita−Baylis−Hillman Reaction

(2011) Fangrui Zhong et al.   ORGANIC LETTERS

Diversity through phosphine catalysis identifies octahydro-1,6-naphthyridin-4-ones as activators of endothelium-driven immunity

(2011) D. Cruz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Asymmetric [3+2] Cycloadditions of Allenoates and Dual Activated Olefins Catalyzed by Simple Bifunctional N-Acyl Aminophosphines

(2010) Hua Xiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic synthesis of spiro compounds via a cascade Michael–Michael-aldol reaction

(2010) Xavier Companyó et al.   CHEMICAL COMMUNICATIONS

An Unexpected Phosphine-Catalyzed Regio- and Diastereoselective [4+1] Annulation Reaction of Modified Allylic Compounds with Activated Enones

(2010) Zuliang Chen et al.   Chemistry-An Asian Journal

2-(Acetoxymethyl)buta-2,3-dienoate, a Versatile 1,4-Biselectrophile for Phosphine-Catalyzed (4 +n) Annulations with 1,n-Bisnucleophiles (n= 1, 2)

(2010) Qiongmei Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phosphine-Catalyzed Domino Reaction: Highly Stereoselective Synthesis oftrans-2,3-Dihydrobenzofurans from SalicylN-Thiophosphinyl Imines and Allylic Carbonates

(2010) Peizhong Xie et al.   ORGANIC LETTERS

Highly enantio-, regio- and diastereo-selective one-pot [2 + 3]-cycloaddition reaction via isomerization of 3-butynoates to allenoates,

(2010) Magesh Sampath et al.   Chemical Science

PPh3-catalyzed [2 + 2 + 2] and [4 + 2] annulations: synthesis of highly substituted 1,2-dihydropyridines (DHPs)

(2009) Huimin Liu et al.   CHEMICAL COMMUNICATIONS

Enantioselective catalysis and complexity generation from allenoates

(2009) Bryan J. Cowen et al.   CHEMICAL SOCIETY REVIEWS

Phosphine-Promoted [3 + 3] Annulations of Aziridines With Allenoates: Facile Entry Into Highly Functionalized Tetrahydropyridines

(2009) Hongchao Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of β-(3-Hydroxypyrazol-1-yl) Ketones Using an Organocatalyzed Michael Addition Reaction

(2009) Sanjib Gogoi et al.   ORGANIC LETTERS

Enantioselective Phosphine Organocatalysis

(2009) Angela Marinetti et al.   SYNLETT

Phosphine-triggered synthesis of functionalized cyclic compounds

(2008) Long-Wu Ye et al.   CHEMICAL SOCIETY REVIEWS

Mechanism, Regioselectivity, and the Kinetics of Phosphine-Catalyzed [3+2] Cycloaddition Reactions of Allenoates and Electron-Deficient Alkenes

(2008) Yong Liang et al.   CHEMISTRY-A EUROPEAN JOURNAL

2-Phospha[3]ferrocenophanes with Planar Chirality: Synthesis and Use in Enantioselective Organocatalytic [3 + 2] Cyclizations

(2008) Arnaud Voituriez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cooperative, Highly Enantioselective Phosphinothiourea Catalysis of Imine−Allene [3 + 2] Cycloadditions

(2008) Yuan-Qing Fang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Phosphine-Catalyzed [3 + 2] Annulation Reaction of Modified Allylic Compounds andN-Tosylimines

(2008) Suqing Zheng et al.   ORGANIC LETTERS

An Unexpected Phosphine-Catalyzed [3 + 2] Annulation. Synthesis of Highly Functionalized Cyclopentenes

(2008) Zheng Lu et al.   ORGANIC LETTERS