Hepatic 3D cultures but not 2D cultures preserve specific transporter activity for acetaminophen-induced hepatotoxicity

Title
Hepatic 3D cultures but not 2D cultures preserve specific transporter activity for acetaminophen-induced hepatotoxicity
Authors
Keywords
Primary human hepatocytes, 2D culture, 3D culture, Acetaminophen, Drug metabolism
Journal
ARCHIVES OF TOXICOLOGY
Volume 87, Issue 8, Pages 1581-1593
Publisher
Springer Nature
Online
2013-05-31
DOI
10.1007/s00204-013-1080-y

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