Fibroblasts Influence Survival and Therapeutic Response in a 3D Co-Culture Model

The quest to overcome resistance to EGFR-targeted therapies in cancer

(2013) Curtis R Chong et al.   NATURE MEDICINE

Activation of an IL6 Inflammatory Loop Mediates Trastuzumab Resistance in HER2+ Breast Cancer by Expanding the Cancer Stem Cell Population

(2012) Hasan Korkaya et al.   MOLECULAR CELL

Molecular characterization of novel trispecific ErbB-cMet-IGF1R antibodies and their antigen-binding properties

(2012) R. Castoldi et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Pleural Mesothelioma Instigates Tumor-Associated Fibroblasts To Promote Progression via a Malignant Cytokine Network

(2011) Qi Li et al.   AMERICAN JOURNAL OF PATHOLOGY

Breast Cancer Cells Induce Cancer-Associated Fibroblasts to Secrete Hepatocyte Growth Factor to Enhance Breast Tumorigenesis

(2011) Shiaw-Wei Tyan et al.   PLoS One

Epidermal growth factor receptor and vascular endothelial growth factor receptor 2 are specific biomarkers in triple-negative breast cancer. Results from a controlled randomized trial with long-term follow-up

(2010) Lisa Rydén et al.   BREAST CANCER RESEARCH AND TREATMENT

Tumor–stroma ratio in the primary tumor is a prognostic factor in early breast cancer patients, especially in triple-negative carcinoma patients

(2010) Esther M. de Kruijf et al.   BREAST CANCER RESEARCH AND TREATMENT

Hallmarks of cancer: Interactions with the tumor stroma

(2010) Kristian Pietras et al.   EXPERIMENTAL CELL RESEARCH

Stromal biology and therapy in pancreatic cancer

(2010) A. Neesse et al.   GUT

Chemokines at the crossroads of tumor-fibroblast interactions that promote malignancy

(2010) Pravin Mishra et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The Role of Tumor Stroma in Cancer Progression and Prognosis: Emphasis on Carcinoma-Associated Fibroblasts and Non-small Cell Lung Cancer

(2010) Roy M. Bremnes et al.   Journal of Thoracic Oncology

Interactions with Fibroblasts Are Distinct in Basal-Like and Luminal Breast Cancers

(2010) J. T. Camp et al.   MOLECULAR CANCER RESEARCH

A Primary Xenograft Model of Small-Cell Lung Cancer Reveals Irreversible Changes in Gene Expression Imposed by Culture In vitro

(2009) V. C. Daniel et al.   CANCER RESEARCH

Tumor-stromal interactions with direct cell contacts enhance proliferation of human pancreatic carcinoma cells

(2009) Hayato Fujita et al.   CANCER SCIENCE

Hepatocyte Growth Factor Reduces Susceptibility to an Irreversible Epidermal Growth Factor Receptor Inhibitor in EGFR-T790M Mutant Lung Cancer

(2009) T. Yamada et al.   CLINICAL CANCER RESEARCH

A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer

(2009) Pierre Farmer et al.   NATURE MEDICINE

Role of Stromal Fibroblasts in Cancer: Promoting or Impeding?

(2009) Flora Angeli et al.   TUMOR BIOLOGY

Role of cMET expression in non-small-cell lung cancer patients treated with EGFR tyrosine kinase inhibitors

(2008) P. A. Zucali et al.   ANNALS OF ONCOLOGY