Advances in the formation, use and understanding of multi-cellular spheroids

Tumor-Endothelial Cell Three-dimensional Spheroids: New Aspects to Enhance Radiation and Drug Therapeutics

(2014) Meenakshi Upreti et al.   Translational Oncology

Mechanotransduction is enhanced by the synergistic action of heterotypic cell interactions and TGF-β1

(2012) Jacquelyn Youssef et al.   FASEB JOURNAL

Pannexin1 Drives Multicellular Aggregate Compaction via a Signaling Cascade That Remodels the Actin Cytoskeleton

(2012) Brian A. Bao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stacking of aligned cell sheets for layer-by-layer control of complex tissue structure

(2011) Corin Williams et al.   BIOMATERIALS

Continuously perfused microbubble array for 3D tumor spheroid model

(2011) Sivaprakash Agastin et al.   Biomicrofluidics

Creation of an in vitro microenvironment to enhance human fetal synovium-derived stem cell chondrogenesis

(2011) Jingting Li et al.   CELL AND TISSUE RESEARCH

The liquid overlay technique is the key to formation of co-culture spheroids consisting of primary osteoblasts, fibroblasts and endothelial cells

(2011) Wolfgang Metzger et al.   CYTOTHERAPY

Human Breast Cancer Histoid

(2011) Pavinder Kaur et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Paclitaxel Tumor-Priming Enhances siRNA Delivery and Transfection in 3-Dimensional Tumor Cultures

(2011) Ho Lun Wong et al.   MOLECULAR PHARMACEUTICS

Cardiac Cell Sheet Transplantation Improves Damaged Heart Function via Superior Cell Survival in Comparison with Dissociated Cell Injection

(2011) Hidekazu Sekine et al.   TISSUE ENGINEERING PART A

Directed self-assembly of large scaffold-free multi-cellular honeycomb structures

(2011) Nalin Tejavibulya et al.   Biofabrication

High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array

(2010) Yi-Chung Tung et al.   ANALYST

Enhanced Chondrogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells in Low Oxygen Environment Micropellet Cultures

(2010) Brandon D. Markway et al.   CELL TRANSPLANTATION

Finite-size corrections to scaling behavior in sorted cell aggregates

(2010) A. V. Klopper et al.   EUROPEAN PHYSICAL JOURNAL E

Connexon-mediated cell adhesion drives microtissue self-assembly

(2010) Brian Bao et al.   FASEB JOURNAL

In vitro maturation of oocytes via the pre-fabricated self-assembled artificial human ovary

(2010) Stephan P. Krotz et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Preparation of arrays of cell spheroids and spheroid-monolayer cocultures within a microfluidic device

(2010) Tomoaki Okuyama et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

A Review of Three-Dimensional In Vitro Tissue Models for Drug Discovery and Transport Studies

(2010) Nelita T. Elliott et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

A multicellular spheroid formation and extraction chip using removable cell trapping barriers

(2010) Hye-Jin Jin et al.   LAB ON A CHIP

Self-Assembly and Tissue Fusion of Toroid-Shaped Minimal Building Units

(2010) Christine M. Livoti et al.   TISSUE ENGINEERING PART A

Tissue engineering by self-assembly and bio-printing of living cells

(2010) Karoly Jakab et al.   Biofabrication

Organ printing: Tissue spheroids as building blocks

(2009) Vladimir Mironov et al.   BIOMATERIALS

Microfluidic system for formation of PC-3 prostate cancer co-culture spheroids

(2009) Amy Y. Hsiao et al.   BIOMATERIALS

Prediction of Drug Response in Breast Cancer Using Integrative Experimental/Computational Modeling

(2009) H. B. Frieboes et al.   CANCER RESEARCH

Hypoxia induced paclitaxel resistance in human ovarian cancers via hypoxia-inducible factor 1α

(2009) Lei Huang et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Three-dimensional cell culture array using magnetic force-based cell patterning for analysis of invasive capacity of BALB/3T3/v-src

(2009) Mina Okochi et al.   LAB ON A CHIP

Engineering microscale cellular niches for three-dimensional multicellular co-cultures

(2009) Carlos P. Huang et al.   LAB ON A CHIP

Dynamic Three-Dimensional Culture Methods Enhance Mesenchymal Stem Cell Properties and Increase Therapeutic Potential

(2009) Jessica E. Frith et al.   TISSUE ENGINEERING PART C-METHODS

Use of antibodies and immunoconjugates for the therapy of more accessible cancers

(2008) Robert M. Sharkey et al.   ADVANCED DRUG DELIVERY REVIEWS

Antibody tumor penetration: Transport opposed by systemic and antigen-mediated clearance

(2008) Greg M. Thurber et al.   ADVANCED DRUG DELIVERY REVIEWS

Effects of Initial Cell Seeding in Self Assembly of Articular Cartilage

(2008) Christopher M. Revell et al.   ANNALS OF BIOMEDICAL ENGINEERING

Modeling the Influence of the E-Cadherin-β-Catenin Pathway in Cancer Cell Invasion: A Multiscale Approach

(2008) Ignacio Ramis-Conde et al.   BIOPHYSICAL JOURNAL

Application of magnetic force-based cell patterning for controlling cell-cell interactions in angiogenesis

(2008) Kosuke Ino et al.   BIOTECHNOLOGY AND BIOENGINEERING

Controlling cell position in complex heterotypic 3D microtissues by tissue fusion

(2008) Adam P. Rago et al.   BIOTECHNOLOGY AND BIOENGINEERING

Predicting drug pharmacokinetics and effect in vascularized tumors using computer simulation

(2008) John P. Sinek et al.   JOURNAL OF MATHEMATICAL BIOLOGY

Tensile forces govern germ-layer organization in zebrafish

(2008) M. Krieg et al.   NATURE CELL BIOLOGY

Spheroid-based engineering of a human vasculature in mice

(2008) Abdullah Alajati et al.   NATURE METHODS

Invasion emerges from cancer cell adaptation to competitive microenvironments: Quantitative predictions from multiscale mathematical models

(2008) Vito Quaranta et al.   SEMINARS IN CANCER BIOLOGY

Cytoskeletal-Mediated Tension Modulates the Directed Self-Assembly of Microtissues

(2008) Dylan M. Dean et al.   TISSUE ENGINEERING PART A