The Spatiotemporal Pattern of Glis3 Expression Indicates a Regulatory Function in Bipotent and Endocrine Progenitors during Early Pancreatic Development and in Beta, PP and Ductal Cells

Plasticity and Dedifferentiation within the Pancreas: Development, Homeostasis, and Disease

(2015) Sapna Puri et al.   Cell Stem Cell

Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors

(2015) M. G. De Vas et al.   DEVELOPMENT

Retinoic Acid-Related Orphan Receptor γ (RORγ): A Novel Participant in the Diurnal Regulation of Hepatic Gluconeogenesis and Insulin Sensitivity

(2014) Yukimasa Takeda et al.   PLoS Genetics

Control of Cell Identity in Pancreas Development and Regeneration

(2013) Ben Z. Stanger et al.   GASTROENTEROLOGY

The Krüppel-Like Protein Gli-Similar 3 (Glis3) Functions as a Key Regulator of Insulin Transcription

(2013) Gary T. ZeRuth et al.   MOLECULAR ENDOCRINOLOGY

Replication Study for the Association of 9 East Asian GWAS-Derived Loci with Susceptibility to Type 2 Diabetes in a Japanese Population

(2013) Kensuke Sakai et al.   PLoS One

New findings in pancreatic and intestinal endocrine development to advance regenerative medicine

(2013) Peter J. Carolan et al.   Current Opinion in Endocrinology Diabetes and Obesity

GLIS3, a Susceptibility Gene for Type 1 and Type 2 Diabetes, Modulates Pancreatic Beta Cell Apoptosis via Regulation of a Splice Variant of the BH3-Only Protein Bim

(2013) Tatiane C. Nogueira et al.   PLoS Genetics

Sustained expression of the transcription factor GLIS3 is required for normal beta cell function in adults

(2012) Yisheng Yang et al.   EMBO Molecular Medicine

Glis3 regulates neurogenin 3 expression in pancreatic β-cells and interacts with its activator, Hnf6

(2012) Yong-Sik Kim et al.   MOLECULES AND CELLS

Ghrelin Expression in the Mouse Pancreas Defines a Unique Multipotent Progenitor Population

(2012) Luis Arnes et al.   PLoS One

Lineage determinants in early endocrine development

(2012) Sebastian Rieck et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Deconstructing Pancreas Developmental Biology

(2012) C. M. Benitez et al.   Cold Spring Harbor Perspectives in Biology

Polycystic kidney disease: The complexity of planar cell polarity and signaling during tissue regeneration and cyst formation

(2011) Hester Happé et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Progenitor cell domains in the developing and adult pancreas

(2011) Janel L. Kopp et al.   CELL CYCLE

Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas

(2011) J. L. Kopp et al.   DEVELOPMENT

Pancreas organogenesis: From bud to plexus to gland

(2011) Fong Cheng Pan et al.   DEVELOPMENTAL DYNAMICS

Historical Perspective: Beginnings of the  -Cell: Current Perspectives in  -Cell Development

(2011) P. A. Seymour et al.   DIABETES

The Krüppel-like zinc finger protein GLIS3 transactivates neurogenin 3 for proper fetal pancreatic islet differentiation in mice

(2011) Y. Yang et al.   DIABETOLOGIA

MafA and MafB activity in pancreatic β cells

(2011) Yan Hang et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Nkx6 Transcription Factors and Ptf1a Function as Antagonistic Lineage Determinants in Multipotent Pancreatic Progenitors

(2010) Ashleigh E. Schaffer et al.   DEVELOPMENTAL CELL

MafA and MafB Regulate Genes Critical to  -Cells in a Unique Temporal Manner

(2010) I. Artner et al.   DIABETES

Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people

(2010) T. W. Boesgaard et al.   DIABETOLOGIA

Novel GLIS3 mutations demonstrate an extended multisystem phenotype

(2010) P Dimitri et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

(2010) Josée Dupuis et al.   NATURE GENETICS

Variants from GIPR, TCF7L2, DGKB, MADD, CRY2, GLIS3, PROX1, SLC30A8 and IGF1 Are Associated with Glucose Metabolism in the Chinese

(2010) Cheng Hu et al.   PLoS One

A murine model of neonatal diabetes mellitus inGlis3-deficient mice

(2009) Naoki Watanabe et al.   FEBS LETTERS

Transcription Factor Glis3, a Novel Critical Player in the Regulation of Pancreatic  -Cell Development and Insulin Gene Expression

(2009) H. S. Kang et al.   MOLECULAR AND CELLULAR BIOLOGY

Glis3 Is Associated with Primary Cilia and Wwtr1/TAZ and Implicated in Polycystic Kidney Disease

(2009) H. S. Kang et al.   MOLECULAR AND CELLULAR BIOLOGY

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

(2009) Jeffrey C Barrett et al.   NATURE GENETICS

The Krüppel-like zinc finger protein Glis3 directly and indirectly activates insulin gene transcription

(2009) Yisheng Yang et al.   NUCLEIC ACIDS RESEARCH

Polycystic Kidney Disease in the Medaka (Oryzias latipes) pc Mutant Caused by a Mutation in the Gli-Similar3 (glis3) Gene

(2009) Hisashi Hashimoto et al.   PLoS One

Functional analysis of the zinc finger and activation domains of Glis3 and mutant Glis3(NDH1)

(2008) Ju Youn Beak et al.   NUCLEIC ACIDS RESEARCH