Sustained expression of the transcription factor GLIS3 is required for normal beta cell function in adults

Association of Genetic Loci With Glucose Levels in Childhood and Adolescence: A Meta-Analysis of Over 6,000 Children

(2011) A. Barker et al.   DIABETES

The Krüppel-like zinc finger protein GLIS3 transactivates neurogenin 3 for proper fetal pancreatic islet differentiation in mice

(2011) Y. Yang et al.   DIABETOLOGIA

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

(2011) Yoon Shin Cho et al.   NATURE GENETICS

Variants in GLIS3 and CRY2 Are Associated with Type 2 Diabetes and Impaired Fasting Glucose in Chinese Hans

(2011) Chen Liu et al.   PLoS One

Effects of 16 Genetic Variants on Fasting Glucose and Type 2 Diabetes in South Asians: ADCY5 and GLIS3 Variants May Predispose to Type 2 Diabetes

(2011) Simon D. Rees et al.   PLoS One

Pancreatic β Cells Require NeuroD to Achieve and Maintain Functional Maturity

(2010) Chunyan Gu et al.   Cell Metabolism

Cyclin D2 Is Essential for the Compensatory  -Cell Hyperplastic Response to Insulin Resistance in Rodents

(2010) S. Georgia et al.   DIABETES

Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people

(2010) T. W. Boesgaard et al.   DIABETOLOGIA

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

(2010) Josée Dupuis et al.   NATURE GENETICS

A murine model of neonatal diabetes mellitus inGlis3-deficient mice

(2009) Naoki Watanabe et al.   FEBS LETTERS

Transcription Factor Glis3, a Novel Critical Player in the Regulation of Pancreatic  -Cell Development and Insulin Gene Expression

(2009) H. S. Kang et al.   MOLECULAR AND CELLULAR BIOLOGY

Minireview: Meeting the Demand for Insulin: Molecular Mechanisms of Adaptive Postnatal ß-Cell Mass Expansion

(2009) Mira M. Sachdeva et al.   MOLECULAR ENDOCRINOLOGY

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

(2009) Jeffrey C Barrett et al.   NATURE GENETICS

The Krüppel-like zinc finger protein Glis3 directly and indirectly activates insulin gene transcription

(2009) Yisheng Yang et al.   NUCLEIC ACIDS RESEARCH

Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function

(2009) S. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucolipotoxicity: Fuel Excess and β-Cell Dysfunction

(2008) Vincent Poitout et al.   ENDOCRINE REVIEWS