New findings in pancreatic and intestinal endocrine development to advance regenerative medicine

Notch-mediated patterning and cell fate allocation of pancreatic progenitor cells

(2012) S. Afelik et al.   DEVELOPMENT

A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation

(2012) H. P. Shih et al.   DEVELOPMENT

Arx is required for normal enteroendocrine cell development in mice and humans

(2012) Aiping Du et al.   DEVELOPMENTAL BIOLOGY

Maturation of Human Embryonic Stem Cell-Derived Pancreatic Progenitors Into Functional Islets Capable of Treating Pre-existing Diabetes in Mice

(2012) A. Rezania et al.   DIABETES

Overlap of Endocrine Hormone Expression in the Mouse Intestine Revealed by Transcriptional Profiling and Flow Cytometry

(2012) Abdella M. Habib et al.   ENDOCRINOLOGY

Generation of functional insulin-producing cells in the gut by Foxo1 ablation

(2012) Chutima Talchai et al.   NATURE GENETICS

A Scalable System for Production of Functional Pancreatic Progenitors from Human Embryonic Stem Cells

(2012) Thomas C. Schulz et al.   PLoS One

The Homeodomain-Containing Transcription Factors Arx and Pax4 Control Enteroendocrine Subtype Specification in Mice

(2012) Anthony Beucher et al.   PLoS One

Mind bomb 1 is required for pancreatic  -cell formation

(2012) S. Horn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ptf1a-mediated control of Dll1 reveals an alternative to the lateral inhibition mechanism

(2011) J. Ahnfelt-Ronne et al.   DEVELOPMENT

Blood vessels restrain pancreas branching, differentiation and growth

(2011) J. Magenheim et al.   DEVELOPMENT

Ngn3+ endocrine progenitor cells control the fate and morphogenesis of pancreatic ductal epithelium

(2011) Judith Magenheim et al.   DEVELOPMENTAL BIOLOGY

Pancreatic β Cell Identity Is Maintained by DNA Methylation-Mediated Repression of Arx

(2011) Sangeeta Dhawan et al.   DEVELOPMENTAL CELL

Pancreas organogenesis: From bud to plexus to gland

(2011) Fong Cheng Pan et al.   DEVELOPMENTAL DYNAMICS

Basic helix-loop-helix transcription factors and enteroendocrine cell differentiation

(2011) H. J. Li et al.   DIABETES OBESITY & METABOLISM

INS GFP/w human embryonic stem cells facilitate isolation of in vitro derived insulin-producing cells

(2011) S. J. Micallef et al.   DIABETOLOGIA

The functional and molecular characterisation of human embryonic stem cell-derived insulin-positive cells compared with adult pancreatic beta cells

(2011) C. L. Basford et al.   DIABETOLOGIA

Cell-surface markers for the isolation of pancreatic cell types derived from human embryonic stem cells

(2011) Olivia G Kelly et al.   NATURE BIOTECHNOLOGY

Chromatin "Prepattern" and Histone Modifiers in a Fate Choice for Liver and Pancreas

(2011) C.-R. Xu et al.   SCIENCE

Pancreatic Mesenchyme Regulates Epithelial Organogenesis throughout Development

(2011) Limor Landsman et al.   PLOS BIOLOGY

Epithelial: Endothelial cross-talk regulates exocrine differentiation in developing pancreas

(2010) Christophe E. Pierreux et al.   DEVELOPMENTAL BIOLOGY

Nkx6 Transcription Factors and Ptf1a Function as Antagonistic Lineage Determinants in Multipotent Pancreatic Progenitors

(2010) Ashleigh E. Schaffer et al.   DEVELOPMENTAL CELL

Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro

(2010) Jason R. Spence et al.   NATURE

The Ectopic Expression of Pax4 in the Mouse Pancreas Converts Progenitor Cells into α and Subsequently β Cells

(2009) Patrick Collombat et al.   CELL

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Developmental biology of the pancreas: A comprehensive review

(2008) George K. Gittes   DEVELOPMENTAL BIOLOGY