Evolution of Pentameric Ligand-Gated Ion Channels: Pro-Loop Receptors

Functional Chimeras of GLIC Obtained by Adding the Intracellular Domain of Anion- and Cation-Conducting Cys-Loop Receptors

(2015) Nelli Mnatsakanyan et al.   BIOCHEMISTRY

Correlating Structural and Energetic Changes in Glycine Receptor Activation

(2015) Suzanne Scott et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complex archaea that bridge the gap between prokaryotes and eukaryotes

(2015) Anja Spang et al.   NATURE

Convergence of ion channel genome content in early animal evolution

(2015) Benjamin J. Liebeskind et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Current Methods for Automated Filtering of Multiple Sequence Alignments Frequently Worsen Single-Gene Phylogenetic Inference

(2015) Ge Tan et al.   SYSTEMATIC BIOLOGY

Molecular basis for convergent evolution of glutamate recognition by pentameric ligand-gated ion channels

(2015) Timothy Lynagh et al.   Scientific Reports

A Predicted Binding Site for Cholesterol on the GABAA Receptor

(2014) Jérôme Hénin et al.   BIOPHYSICAL JOURNAL

Genomes in turmoil: quantification of genome dynamics in prokaryote supergenomes

(2014) Pere Puigbò et al.   BMC BIOLOGY

The ctenophore genome and the evolutionary origins of neural systems

(2014) Leonid L. Moroz et al.   NATURE

Crystal structure of a human GABAA receptor

(2014) Paul S. Miller et al.   NATURE

X-ray structure of the mouse serotonin 5-HT3 receptor

(2014) Ghérici Hassaine et al.   NATURE

The InterPro protein families database: the classification resource after 15 years

(2014) Alex Mitchell et al.   NUCLEIC ACIDS RESEARCH

Evidence for accumulation of Synechococcus elongatus (Cyanobacteria: Cyanophyceae) in the tissues of the oyster Crassostrea gigas (Mollusca: Bivalvia)

(2014) Omar Hernando Avila-Poveda et al.   TISSUE & CELL

The chimerical and multifaceted marine acoel Symsagittifera roscoffensis: from photosymbiosis to brain regeneration

(2014) Xavier Bailly et al.   Frontiers in Microbiology

Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels

(2013) Ludovic Sauguet et al.   EMBO JOURNAL

Multisite Binding of a General Anesthetic to the Prokaryotic PentamericErwinia chrysanthemiLigand-gated Ion Channel (ELIC)

(2013) Radovan Spurny et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Experimental determination of the vertical alignment between the second and third transmembrane segments of muscle nicotinic acetylcholine receptors

(2013) Nelli Mnatsakanyan et al.   JOURNAL OF NEUROCHEMISTRY

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

(2013) K. Katoh et al.   MOLECULAR BIOLOGY AND EVOLUTION

Pan genome of the phytoplankton Emiliania underpins its global distribution

(2013) Betsy A. Read et al.   NATURE

The Capsaspora genome reveals a complex unicellular prehistory of animals

(2013) Hiroshi Suga et al.   Nature Communications

Molecular Cloning and Characterization of Novel Glutamate-Gated Chloride Channel Subunits from Schistosoma mansoni

(2013) Vanessa Dufour et al.   PLoS Pathogens

Premetazoan genome evolution and the regulation of cell differentiation in the choanoflagellate Salpingoeca rosetta

(2013) Stephen R Fairclough et al.   GENOME BIOLOGY

Reversal of ion-charge selectivity renders the pentameric ligand-gated ion channel GLIC insensitive to anaesthetics

(2012) Tommy Tillman et al.   BIOCHEMICAL JOURNAL

Structure and Pharmacology of Pentameric Receptor Channels: From Bacteria to Brain

(2012) Pierre-Jean Corringer et al.   STRUCTURE

Identifying bacterial and archaeal homologs of pentameric ligand-gated ion channel (pLGIC) family using domain-based and alignment-based approaches

(2011) Gloria Rendon et al.   Channels

Principles of activation and permeation in an anion-selective Cys-loop receptor

(2011) Ryan E. Hibbs et al.   NATURE

InterPro in 2011: new developments in the family and domain prediction database

(2011) S. Hunter et al.   NUCLEIC ACIDS RESEARCH

Interactive Tree Of Life v2: online annotation and display of phylogenetic trees made easy

(2011) I. Letunic et al.   NUCLEIC ACIDS RESEARCH

HMMER web server: interactive sequence similarity searching

(2011) R. D. Finn et al.   NUCLEIC ACIDS RESEARCH

Functional prokaryotic-eukaryotic chimera from the pentameric ligand-gated ion channel family

(2011) G. Duret et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Survey of Branch Support Methods Demonstrates Accuracy, Power, and Robustness of Fast Likelihood-based Approximation Schemes

(2011) Maria Anisimova et al.   SYSTEMATIC BIOLOGY

Ligand Activation of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC

(2011) Iwan Zimmermann et al.   PLOS BIOLOGY

The dynamic genome of Hydra

(2010) Jarrod A. Chapman et al.   NATURE

The Amphimedon queenslandica genome and the evolution of animal complexity

(2010) Mansi Srivastava et al.   NATURE

FastTree 2 – Approximately Maximum-Likelihood Trees for Large Alignments

(2010) Morgan N. Price et al.   PLoS One

trimAl: a tool for automated alignment trimming in large-scale phylogenetic analyses

(2009) S. Capella-Gutierrez et al.   BIOINFORMATICS

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

phyloXML: XML for evolutionary biology and comparative genomics

(2009) Mira V Han et al.   BMC BIOINFORMATICS

Aplysia cys-loop Glutamate-Gated Chloride Channels Reveal Convergent Evolution of Ligand Specificity

(2009) JacSue Kehoe et al.   JOURNAL OF MOLECULAR EVOLUTION

GABA-Induced Intersubunit Conformational Movement in the GABAA Receptor  1M1- 2M3 Transmembrane Subunit Interface: Experimental Basis for Homology Modeling of an Intravenous Anesthetic Binding Site

(2009) M. Bali et al.   JOURNAL OF NEUROSCIENCE

Atomic structure and dynamics of pentameric ligand-gated ion channels: new insight from bacterial homologues

(2009) Pierre-Jean Corringer et al.   JOURNAL OF PHYSIOLOGY-LONDON

Noisy: Identification of problematic columns in multiple sequence alignments

(2008) Andreas WM Dress et al.   Algorithms for Molecular Biology

An Improved General Amino Acid Replacement Matrix

(2008) S. Q. Le et al.   MOLECULAR BIOLOGY AND EVOLUTION

The Trichoplax genome and the nature of placozoans

(2008) Mansi Srivastava et al.   NATURE

Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation

(2008) Nicolas Bocquet et al.   NATURE

The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans

(2008) Nicole King et al.   NATURE

X-ray structure of a prokaryotic pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

Mesophilic crenarchaeota: proposal for a third archaeal phylum, the Thaumarchaeota

(2008) Céline Brochier-Armanet et al.   NATURE REVIEWS MICROBIOLOGY

PROMALS3D: a tool for multiple protein sequence and structure alignments

(2008) Jimin Pei et al.   NUCLEIC ACIDS RESEARCH