Correlating Structural and Energetic Changes in Glycine Receptor Activation

Catch-and-Hold Activation of Muscle Acetylcholine Receptors Having Transmitter Binding Site Mutations

(2014) Prasad Purohit et al.   BIOPHYSICAL JOURNAL

Crystal structure of a human GABAA receptor

(2014) Paul S. Miller et al.   NATURE

X-ray structure of the mouse serotonin 5-HT3 receptor

(2014) Ghérici Hassaine et al.   NATURE

X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors

(2014) Thorsten Althoff et al.   NATURE

The impact of human hyperekplexia mutations on glycine receptor structure and function

(2014) Anna Bode et al.   Molecular Brain

Analysis of Hyperekplexia Mutations Identifies Transmembrane Domain Rearrangements That Mediate Glycine Receptor Activation

(2013) Anna Bode et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New Hyperekplexia Mutations Provide Insight into Glycine Receptor Assembly, Trafficking, and Activation Mechanisms

(2013) Anna Bode et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Energy and Work of a Ligand-Gated Ion Channel

(2013) Anthony Auerbach   JOURNAL OF MOLECULAR BIOLOGY

Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation

(2013) L. Sauguet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional anatomy of an allosteric protein

(2013) Prasad Purohit et al.   Nature Communications

Stoichiometry and Subunit Arrangement of α1β Glycine Receptors As Determined by Atomic Force Microscopy

(2012) Zhe Yang et al.   BIOCHEMISTRY

The startle syndromes: Physiology and treatment

(2012) Yasmine E. M. Dreissen et al.   EPILEPSIA

The  1K276E Startle Disease Mutation Reveals Multiple Intermediate States in the Gating of Glycine Receptors

(2012) R. Lape et al.   JOURNAL OF NEUROSCIENCE

Stoichiometry of the Human Glycine Receptor Revealed by Direct Subunit Counting

(2012) N. Durisic et al.   JOURNAL OF NEUROSCIENCE

Principles of activation and permeation in an anion-selective Cys-loop receptor

(2011) Ryan E. Hibbs et al.   NATURE

Linking the Acetylcholine Receptor-Channel Agonist-Binding Sites with the Gate

(2010) David J. Cadugan et al.   BIOPHYSICAL JOURNAL

What single-channel analysis tells us of the activation mechanism of ligand-gated channels: the case of the glycine receptor

(2009) Lucia G. Sivilotti   JOURNAL OF PHYSIOLOGY-LONDON

The gating isomerization of neuromuscular acetylcholine receptors

(2009) Anthony Auerbach   JOURNAL OF PHYSIOLOGY-LONDON

Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation

(2008) Nicolas Bocquet et al.   NATURE

X-ray structure of a prokaryotic pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

Pore-opening mechanism of the nicotinic acetylcholine receptor evinced by proton transfer

(2008) Gisela D Cymes et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Unliganded gating of acetylcholine receptor channels

(2008) P. Purohit et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA