The Crosstalk between Nrf2 and TGF-β1 in the Epithelial-Mesenchymal Transition of Pancreatic Duct Epithelial Cells
Published 2015 View Full Article
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Title
The Crosstalk between Nrf2 and TGF-β1 in the Epithelial-Mesenchymal Transition of Pancreatic Duct Epithelial Cells
Authors
Keywords
Small interfering RNAs, Vimentin, Pancreatic ducts, Cancer treatment, Inflammation, Luciferase, Carcinogenesis, Epithelial cells
Journal
PLoS One
Volume 10, Issue 7, Pages e0132978
Publisher
Public Library of Science (PLoS)
Online
2015-07-31
DOI
10.1371/journal.pone.0132978
References
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Note: Only part of the references are listed.- CD4+T cells potently induce epithelial-mesenchymal-transition in premalignant and malignant pancreatic ductal epithelial cells–novel implications of CD4+T cells in pancreatic cancer development
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- Luteolin inhibits the Nrf2 signaling pathway and tumor growth in vivo
- (2014) Song Chian et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2014) John D. Hayes et al. TRENDS IN BIOCHEMICAL SCIENCES
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- (2013) Suna Zhou et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Blockage of Nrf2 suppresses the migration and invasion of esophageal squamous cell carcinoma cells in hypoxic microenvironment
- (2013) H. Shen et al. DISEASES OF THE ESOPHAGUS
- Oncogenic functions of the transcription factor Nrf2
- (2013) Irene Gañán-Gómez et al. FREE RADICAL BIOLOGY AND MEDICINE
- The emerging role of the Nrf2-Keap1 signaling pathway in cancer
- (2013) M. C. Jaramillo et al. GENES & DEVELOPMENT
- Knockdown of Nrf2 suppresses glioblastoma angiogenesis by inhibiting hypoxia-induced activation of HIF-1α
- (2013) Xiangjun Ji et al. INTERNATIONAL JOURNAL OF CANCER
- Transforming Growth Factor-β Induces Transcription Factors MafK and Bach1 to Suppress Expression of the Heme Oxygenase-1 Gene
- (2013) Yukari Okita et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of nuclear factor-erythroid 2–related factor (Nrf2) by caveolin-1 promotes stress-induced premature senescence
- (2013) Daniela Volonte et al. MOLECULAR BIOLOGY OF THE CELL
- Nuclear Nrf2 expression is related to a poor survival in pancreatic adenocarcinoma
- (2013) Y. Soini et al. PATHOLOGY RESEARCH AND PRACTICE
- Toward clinical application of the Keap1–Nrf2 pathway
- (2013) Takafumi Suzuki et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- The Nrf2 cell defence pathway: Keap1-dependent and -independent mechanisms of regulation
- (2012) Holly K. Bryan et al. BIOCHEMICAL PHARMACOLOGY
- Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming
- (2012) Yoichiro Mitsuishi et al. CANCER CELL
- The emerging role of the TGFβ tumor suppressor pathway in pancreatic cancer
- (2012) David J. Birnbaum et al. CELL CYCLE
- The transcription factor NF-E2-related Factor 2 (Nrf2): a protooncogene?
- (2012) Phillip Shelton et al. FASEB JOURNAL
- E-cadherin inhibits nuclear accumulation of Nrf2: implications for chemoresistance of cancer cells
- (2012) W. D. Kim et al. JOURNAL OF CELL SCIENCE
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- (2012) Lingmin Zhang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
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- (2012) Dah-Yuu Lu et al. NEURO-ONCOLOGY
- Inhibition of the Nrf2 transcription factor by the alkaloid trigonelline renders pancreatic cancer cells more susceptible to apoptosis through decreased proteasomal gene expression and proteasome activity
- (2012) A Arlt et al. ONCOGENE
- Molecular mechanisms for the regulation of Nrf2-mediated cell proliferation in non-small-cell lung cancers
- (2012) T Yamadori et al. ONCOGENE
- Dimethylfumarate Attenuates Renal Fibrosis via NF-E2-Related Factor 2-Mediated Inhibition of Transforming Growth Factor-β/Smad Signaling
- (2012) Chang Joo Oh et al. PLoS One
- NRF2 Blockade Suppresses Colon Tumor Angiogenesis by Inhibiting Hypoxia-Induced Activation of HIF-1
- (2011) T.-H. Kim et al. CANCER RESEARCH
- Transforming Growth Factor Beta in Pancreatic Cancer
- (2011) Andreas Hilbig et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- Inflammatory Macrophages Induce Nrf2 Transcription Factor-dependent Proteasome Activity in Colonic NCM460 Cells and Thereby Confer Anti-apoptotic Protection
- (2011) Susanne Sebens et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Loss of E-cadherin expression and outcome among patients with resectable pancreatic adenocarcinomas
- (2011) Seung-Mo Hong et al. MODERN PATHOLOGY
- Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy
- (2011) Adam Lister et al. Molecular Cancer
- Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
- (2011) Gina M. DeNicola et al. NATURE
- Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism
- (2011) D. Ren et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Role of Nrf2 in Migration and Invasion of Human Glioma Cell U251
- (2011) Hao Pan et al. World Neurosurgery
- Gain of Nrf2 Function in Non-Small-Cell Lung Cancer Cells Confers Radioresistance
- (2010) Anju Singh et al. ANTIOXIDANTS & REDOX SIGNALING
- Cancer Chemoprevention Mechanisms Mediated Through the Keap1–Nrf2 Pathway
- (2010) John D. Hayes et al. ANTIOXIDANTS & REDOX SIGNALING
- Oxidative stress, inflammation, and cancer: How are they linked?
- (2010) Simone Reuter et al. FREE RADICAL BIOLOGY AND MEDICINE
- Nrf2-ARE stress response mechanism: A control point in oxidative stress-mediated dysfunctions and chronic inflammatory diseases
- (2010) Shruti Singh et al. FREE RADICAL RESEARCH
- The dynamic roles of TGF-β in cancer
- (2010) Erik Meulmeester et al. JOURNAL OF PATHOLOGY
- Increased cell migration and plasticity in Nrf2-deficient cancer cell lines
- (2010) G Rachakonda et al. ONCOGENE
- Nuclear Factor (Erythroid-Derived 2)-Like 2 Regulates Drug Resistance in Pancreatic Cancer Cells
- (2010) Young Bin Hong et al. PANCREAS
- Up-regulation of L1CAM in Pancreatic Duct Cells Is Transforming Growth Factor 1- and Slug-Dependent: Role in Malignant Transformation of Pancreatic Cancer
- (2009) C. Geismann et al. CANCER RESEARCH
- Mechanism of TGF-β signaling to growth arrest, apoptosis, and epithelial–mesenchymal transition
- (2009) Carl-Henrik Heldin et al. CURRENT OPINION IN CELL BIOLOGY
- Nrf2:INrf2 (Keap1) signaling in oxidative stress
- (2009) James W. Kaspar et al. FREE RADICAL BIOLOGY AND MEDICINE
- Significance of M2-Polarized Tumor-Associated Macrophage in Pancreatic Cancer
- (2009) Hiroshi Kurahara et al. JOURNAL OF SURGICAL RESEARCH
- Inhibition of liver fibrosis by solubilized coenzyme Q10: Role of Nrf2 activation in inhibiting transforming growth factor-β1 expression
- (2009) Hoo-Kyun Choi et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Role of myofibroblasts in innate chemoresistance of pancreatic carcinoma-Epigenetic downregulation of caspases
- (2008) Susanne Sebens Müerköster et al. INTERNATIONAL JOURNAL OF CANCER
- Dual roles of Nrf2 in cancer
- (2008) A LAU et al. PHARMACOLOGICAL RESEARCH
- Nrf2 signaling: An adaptive response pathway for protection against environmental toxic insults
- (2007) W OSBURN et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
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