CD4+T cells potently induce epithelial-mesenchymal-transition in premalignant and malignant pancreatic ductal epithelial cells–novel implications of CD4+T cells in pancreatic cancer development

Tumor-associated macrophages exhibit pro- and anti-inflammatory properties by which they impact on pancreatic tumorigenesis

(2014) Ole Helm et al.   INTERNATIONAL JOURNAL OF CANCER

Tumor necrosis factor-α modulates epithelial mesenchymal transition mediators ZEB2 and S100A4 to promote cholangiocarcinoma progression

(2014) Anchalee Techasen et al.   Journal of Hepato-Biliary-Pancreatic Sciences

L1CAM promotes enrichment of immunosuppressive T cells in human pancreatic cancer correlating with malignant progression

(2014) Evelin Grage-Griebenow et al.   Molecular Oncology

Comparative Characterization of Stroma Cells and Ductal Epithelium in Chronic Pancreatitis and Pancreatic Ductal Adenocarcinoma

(2014) Ole Helm et al.   PLoS One

CD4+ T Lymphocyte Ablation Prevents Pancreatic Carcinogenesis in Mice

(2014) Y. Zhang et al.   Cancer Immunology Research

The fatal alliance of cancer and T cells

(2014) Evelin Grage-Griebenow et al.   OncoImmunology

Immune cells in pancreatic cancer

(2014) Yaqing Zhang et al.   OncoImmunology

Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer

(2013) Y Ino et al.   BRITISH JOURNAL OF CANCER

Cancer statistics, 2013

(2013) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Location, Location, Location: Macrophage Positioning within Tumors Determines Pro- or Antitumor Activity

(2013) Lee B. Rivera et al.   CANCER CELL

Detection of Circulating Pancreas Epithelial Cells in Patients With Pancreatic Cystic Lesions

(2013) Andrew D. Rhim et al.   GASTROENTEROLOGY

Epithelial–Mesenchymal Transition (EMT) Induced by TNF-α Requires AKT/GSK-3β-Mediated Stabilization of Snail in Colorectal Cancer

(2013) Hao Wang et al.   PLoS One

Immune infiltrates as predictive markers of survival in pancreatic cancer patients

(2013) Maria Pia Protti et al.   Frontiers in Physiology

Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors

(2012) Anne-Katrine Bonde et al.   BMC CANCER

Epithelial-Mesenchymal Transition Induced by TNF-  Requires NF- B-Mediated Transcriptional Upregulation of Twist1

(2012) C.-W. Li et al.   CANCER RESEARCH

EMT and Dissemination Precede Pancreatic Tumor Formation

(2012) Andrew D. Rhim et al.   CELL

M2-Polarized Tumor-Associated Macrophage Infiltration of Regional Lymph Nodes Is Associated With Nodal Lymphangiogenesis and Occult Nodal Involvement in pN0 Pancreatic Cancer

(2012) Hiroshi Kurahara et al.   PANCREAS

Comparative Analysis of Dynamic Cell Viability, Migration and Invasion Assessments by Novel Real-Time Technology and Classic Endpoint Assays

(2012) Ridha Limame et al.   PLoS One

Myofibroblast-induced tumorigenicity of pancreatic ductal epithelial cells is L1CAM dependent

(2011) Heiner Schäfer et al.   CARCINOGENESIS

Pancreatic Cancer Alters Human CD4+ T Lymphocyte Function

(2011) Paola Fogar et al.   PANCREAS

Positive Expression of L1-CAM is Associated with Perineural Invasion and Poor Outcome in Pancreatic Ductal Adenocarcinoma

(2010) Qi-Wen Ben et al.   ANNALS OF SURGICAL ONCOLOGY

Up-regulation of L1CAM in Pancreatic Duct Cells Is Transforming Growth Factor  1- and Slug-Dependent: Role in Malignant Transformation of Pancreatic Cancer

(2009) C. Geismann et al.   CANCER RESEARCH

Immune-Induced Epithelial to Mesenchymal Transition In vivo Generates Breast Cancer Stem Cells

(2009) M. Santisteban et al.   CANCER RESEARCH

Significance of M2-Polarized Tumor-Associated Macrophage in Pancreatic Cancer

(2009) Hiroshi Kurahara et al.   JOURNAL OF SURGICAL RESEARCH

Anti-Tumor Necrosis Factor Therapy Inhibits Pancreatic Tumor Growth and Metastasis

(2008) J.-H. Egberts et al.   CANCER RESEARCH