Anaplastic lymphoma kinase: role in cancer pathogenesis and small-molecule inhibitor development for therapy

Epidermal growth factor receptor inhibitors in the treatment of lung cancer: reality and hopes

(2009) Paul Wheatley-Price et al.   CURRENT OPINION IN ONCOLOGY

An Attractive Therapeutic Target, mTOR Pathway, in ALK+ Anaplastic Large Cell Lymphoma

(2008) Jeong Hee Cho-Vega et al.   ADVANCES IN ANATOMIC PATHOLOGY

Elevated levels of PtdIns5P in NPM-ALK transformed cells: Implication of PIKfyve

(2008) S. Coronas et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ALK+ histiocytosis: a novel type of systemic histiocytic proliferative disorder of early infancy

(2008) J. K. C. Chan et al.   BLOOD

ALK- anaplastic large-cell lymphoma is clinically and immunophenotypically different from both ALK+ ALCL and peripheral T-cell lymphoma, not otherwise specified: report from the International Peripheral T-Cell Lymphoma Project

(2008) K. J. Savage et al.   BLOOD

EML4–ALK fusion transcript is not found in gastrointestinal and breast cancers

(2008) Y Fukuyoshi et al.   BRITISH JOURNAL OF CANCER

Genomic Alterations of Anaplastic Lymphoma Kinase May Sensitize Tumors to Anaplastic Lymphoma Kinase Inhibitors

(2008) U. McDermott et al.   CANCER RESEARCH

Identification of Novel Isoforms of the EML4-ALK Transforming Gene in Non-Small Cell Lung Cancer

(2008) Y. L. Choi et al.   CANCER RESEARCH

Regulation of growth factor signaling by FRS2 family docking/scaffold adaptor proteins

(2008) Noriko Gotoh   CANCER SCIENCE

EML4-ALK Fusion Gene and Efficacy of an ALK Kinase Inhibitor in Lung Cancer

(2008) J. P. Koivunen et al.   CLINICAL CANCER RESEARCH

Showering c-MET-dependent cancers with drugs

(2008) Beatrice S. Knudsen et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Pleiotrophin, a multifunctional angiogenic factor: mechanisms and pathways in normal and pathological angiogenesis

(2008) Pablo Perez-Pinera et al.   CURRENT OPINION IN HEMATOLOGY

Inflammatory myofibroblastic tumor and low-grade myofibroblastic sarcoma: a comparative study of clinicopathologic features and further observations on the immunohistochemical profile of myofibroblasts

(2008) Xiaofei Qiu et al.   HUMAN PATHOLOGY

Inflammatory myofibroblastic tumor of the central nervous system and its relationship to inflammatory pseudotumor

(2008) Rebecca S. Swain et al.   HUMAN PATHOLOGY

The Survival-promoting Peptide Y-P30 Enhances Binding of Pleiotrophin to Syndecan-2 and -3 and Supports Its Neuritogenic Activity

(2008) Peter Landgraf et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure and Clinical Relevance of the Epidermal Growth Factor Receptor in Human Cancer

(2008) Amit Kumar et al.   JOURNAL OF CLINICAL ONCOLOGY

EML4-ALK Fusion Is Linked to Histological Characteristics in a Subset of Lung Cancers

(2008) Kentaro Inamura et al.   Journal of Thoracic Oncology

EML4-ALK fusion transcripts, but no NPM-, TPM3-, CLTC-, ATIC-, or TFG-ALK fusion transcripts, in non-small cell lung carcinomas

(2008) Kazuya Shinmura et al.   LUNG CANCER

Identification of ALK as a major familial neuroblastoma predisposition gene

(2008) Yaël P. Mossé et al.   NATURE

Activating mutations in ALK provide a therapeutic target in neuroblastoma

(2008) Rani E. George et al.   NATURE

Oncogenic mutations of ALK kinase in neuroblastoma

(2008) Yuyan Chen et al.   NATURE

Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma

(2008) Isabelle Janoueix-Lerosey et al.   NATURE

A quantitative analysis of kinase inhibitor selectivity

(2008) Mazen W Karaman et al.   NATURE BIOTECHNOLOGY

Neuroblastoma: Biology, Prognosis, and Treatment

(2008) Julie R. Park et al.   PEDIATRIC CLINICS OF NORTH AMERICA

A mouse model for EML4-ALK-positive lung cancer

(2008) M. Soda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammatory myofibroblastic tumours: where are we now?

(2007) B C Gleason et al.   JOURNAL OF CLINICAL PATHOLOGY

Analysis of gene expression profile of TPM3-ALK positive anaplastic large cell lymphoma reveals overlapping and unique patterns with that of NPM-ALK positive anaplastic large cell lymphoma

(2007) Sandra D. Bohling et al.   LEUKEMIA RESEARCH

Development of anaplastic lymphoma kinase (ALK) small-molecule inhibitors for cancer therapy

(2007) Rongshi Li et al.   MEDICINAL RESEARCH REVIEWS