Behavioral and Neurotransmitter Abnormalities in Mice Deficient for Parkin, DJ-1 and Superoxide Dismutase

Evidence of oxidative stress in young and aged DJ-1-deficient mice

(2013) Arjun V. Raman et al.   FEBS LETTERS

Analysis of inflammation-related nigral degeneration and locomotor function in DJ-1 −/− mice

(2013) Thi A Nguyen et al.   Journal of Neuroinflammation

The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo

(2013) E. S. Vincow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DJ-1 protein protects dopaminergic neurons against 6-OHDA/MG-132-induced neurotoxicity in rats

(2012) Shuang-Yong Sun et al.   BRAIN RESEARCH BULLETIN

parkin-induced defects in neurophysiology and locomotion are generated by metabolic dysfunction and not oxidative stress

(2012) A. Vincent et al.   HUMAN MOLECULAR GENETICS

Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit

(2012) Anh H. Pham et al.   HUMAN MOLECULAR GENETICS

Mitochondrial dysfunction and oxidative stress in Parkinson's disease and monogenic parkinsonism

(2012) David N. Hauser et al.   NEUROBIOLOGY OF DISEASE

Human SOD2 Modification by Dopamine Quinones Affects Enzymatic Activity by Promoting Its Aggregation: Possible Implications for Parkinson’s Disease

(2012) Elisa Belluzzi et al.   PLoS One

Overexpression of Parkin Ameliorates Dopaminergic Neurodegeneration Induced by 1- Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine in Mice

(2012) Minjuan Bian et al.   PLoS One

Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson disease

(2012) M. W. C. Rousseaux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Parkin controls dopamine utilization in human midbrain dopaminergic neurons derived from induced pluripotent stem cells

(2012) Houbo Jiang et al.   Nature Communications

DJ-1 modulates the expression of Cu/Zn-superoxide dismutase-1 through the Erk1/2-Elk1 pathway in neuroprotection

(2011) Zhiquan Wang et al.   ANNALS OF NEUROLOGY

Comparative analysis of pathology and behavioural phenotypes in mouse models of Huntington's disease

(2011) Simon P. Brooks et al.   BRAIN RESEARCH BULLETIN

DJ-1 deficiency in astrocytes selectively enhances mitochondrial Complex I inhibitor-induced neurotoxicity

(2011) Steven J. Mullett et al.   JOURNAL OF NEUROCHEMISTRY

Akt Suppresses Retrograde Degeneration of Dopaminergic Axons by Inhibition of Macroautophagy

(2011) H.-C. Cheng et al.   JOURNAL OF NEUROSCIENCE

SOD1 and TDP-43 animal models of amyotrophic lateral sclerosis: recent advances in understanding disease toward the development of clinical treatments

(2011) Peter I. Joyce et al.   MAMMALIAN GENOME

DJ-1 associates with synaptic membranes

(2011) Yukiko Usami et al.   NEUROBIOLOGY OF DISEASE

What Genetics Tells us About the Causes and Mechanisms of Parkinson's Disease

(2011) Olga Corti et al.   PHYSIOLOGICAL REVIEWS

Autosomal recessive mutations in the development of Parkinson’s disease

(2010) Grisel Lopez et al.   Biomarkers in Medicine

Gene–Environment Interactions in Parkinson's Disease: The Importance of Animal Modeling

(2010) M P Horowitz et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Mutant SOD1 and mitochondrial damage alter expression and splicing of genes controlling neuritogenesis in models of neurodegeneration

(2010) Silvia C. Lenzken et al.   HUMAN MUTATION

Genetic Animal Models of Parkinson's Disease

(2010) Ted M. Dawson et al.   NEURON

DJ-1 binds to mitochondrial complex I and maintains its activity

(2009) Takuya Hayashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The effects of parkin suppression on the behaviour, amyloid processing, and cell survival in APP mutant transgenic mice

(2009) Juan Perucho et al.   EXPERIMENTAL NEUROLOGY

DJ-1-deficient mice show less TH-positive neurons in the ventral tegmental area and exhibit non-motoric behavioural impairments

(2009) T. T. Pham et al.   GENES BRAIN AND BEHAVIOR

Formation of a Stabilized Cysteine Sulfinic Acid Is Critical for the Mitochondrial Function of the Parkinsonism Protein DJ-1

(2009) Jeff Blackinton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Absence of nigral degeneration in aged parkin/DJ-1/PINK1 triple knockout mice

(2009) Tohru Kitada et al.   JOURNAL OF NEUROCHEMISTRY

DJ-1 mRNA anatomical localization and cell type identification in the mouse brain

(2009) Zhiguo Xie et al.   NEUROSCIENCE LETTERS

Toxic effects of dopamine metabolism in Parkinson's disease

(2009) Nobutaka Hattori et al.   PARKINSONISM & RELATED DISORDERS

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Parkin Deficiency Increases Vulnerability to Inflammation-Related Nigral Degeneration

(2008) T. C. Frank-Cannon et al.   JOURNAL OF NEUROSCIENCE

Mitochondrial localization of DJ-1 leads to enhanced neuroprotection

(2008) Eunsung Junn et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Intrastriatal CERE-120 (AAV-Neurturin) protects striatal and cortical neurons and delays motor deficits in a transgenic mouse model of Huntington's disease

(2008) Shilpa Ramaswamy et al.   NEUROBIOLOGY OF DISEASE

Free Copper, Ferroxidase and SOD1 Activities, Lipid Peroxidation and NO x Content in the CSF. A Different Marker Profile in Four Neurodegenerative Diseases

(2008) Marie-Catherine Boll et al.   NEUROCHEMICAL RESEARCH

Oxidative insults induce DJ-1 upregulation and redistribution: Implications for neuroprotection

(2008) Nirit Lev et al.   NEUROTOXICOLOGY

Progressive behavioral deficits in DJ-1-deficient mice are associated with normal nigrostriatal function

(2007) Jayanth S. Chandran et al.   NEUROBIOLOGY OF DISEASE