parkin-induced defects in neurophysiology and locomotion are generated by metabolic dysfunction and not oxidative stress

Genetic Manipulation of Genes and Cells in the Nervous System of the Fruit Fly

(2011) Koen J.T. Venken et al.   NEURON

Oxidative stress induces overgrowth of the Drosophila neuromuscular junction

(2011) V. J. Milton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zinc supplement greatly improves the condition of parkin mutant Drosophila

(2010) Nidhi Saini et al.   BIOLOGICAL CHEMISTRY

LRRK2 Kinase Regulates Synaptic Morphology through Distinct Substrates at the Presynaptic and Postsynaptic Compartments of the Drosophila Neuromuscular Junction

(2010) S. Lee et al.   JOURNAL OF NEUROSCIENCE

100 years of Drosophila research and its impact on vertebrate neuroscience: a history lesson for the future

(2010) Hugo J. Bellen et al.   NATURE REVIEWS NEUROSCIENCE

Extended lifespan of Drosophila parkin mutants through sequestration of redox-active metals and enhancement of anti-oxidative pathways

(2010) Nidhi Saini et al.   NEUROBIOLOGY OF DISEASE

Genetic Analysis of Pathways to Parkinson Disease

(2010) John Hardy   NEURON

Genetic Animal Models of Parkinson's Disease

(2010) Ted M. Dawson et al.   NEURON

DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex

(2010) Joo-Young Im et al.   NEUROSCIENCE RESEARCH

High brain lactate is a hallmark of aging and caused by a shift in the lactate dehydrogenase A/B ratio

(2010) J. M. Ross et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin

(2010) E. Ziviani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recent advances in using Drosophila to model neurodegenerative diseases

(2009) Bingwei Lu   APOPTOSIS

Autophagy promotes synapse development inDrosophila

(2009) Wei Shen et al.   JOURNAL OF CELL BIOLOGY

Impaired dopamine release and synaptic plasticity in the striatum ofParkin−/− mice

(2009) Tohru Kitada et al.   JOURNAL OF NEUROCHEMISTRY

Clinical neuroprotection in Parkinson's disease — Still waiting for the breakthrough

(2009) Matthias Löhle et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

SH3 Domains from a Subset of BAR Proteins Define a Ubl-Binding Domain and Implicate Parkin in Synaptic Ubiquitination

(2009) Jean-François Trempe et al.   MOLECULAR CELL

Spike integration and cellular memory in a rhythmic network from Na+/K+ pump current dynamics

(2009) Stefan R Pulver et al.   NATURE NEUROSCIENCE

Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss

(2009) Luke S Tain et al.   NATURE NEUROSCIENCE

Modelling Parkinson’s Disease in Drosophila

(2009) José A. Botella et al.   NEUROMOLECULAR MEDICINE

Mitochondrial function and morphology are impaired inparkin-mutant fibroblasts

(2008) Heather Mortiboys et al.   ANNALS OF NEUROLOGY

Superoxide dismutase overexpression protects dopaminergic neurons in a Drosophila model of Parkinson's disease

(2008) Jose A. Botella et al.   NEUROBIOLOGY OF DISEASE

The PINK1/Parkin pathway regulates mitochondrial morphology

(2008) A. C. Poole et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA