High Mobility Group Box-1 Promotes the Proliferation and Migration of Hepatic Stellate Cells via TLR4-Dependent Signal Pathways of PI3K/Akt and JNK
Published 2013 View Full Article
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Title
High Mobility Group Box-1 Promotes the Proliferation and Migration of Hepatic Stellate Cells via TLR4-Dependent Signal Pathways of PI3K/Akt and JNK
Authors
Keywords
Immune receptor signaling, Liver fibrosis, Transcription factors, Apoptosis, Collagens, Cytokines, Enzyme-linked immunoassays, Membrane receptor signaling
Journal
PLoS One
Volume 8, Issue 5, Pages e64373
Publisher
Public Library of Science (PLoS)
Online
2013-05-17
DOI
10.1371/journal.pone.0064373
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Note: Only part of the references are listed.- High-mobility group box-1 protein induces mucin 8 expression through the activation of the JNK and PI3K/Akt signal pathways in human airway epithelial cells
- (2012) Dong Eun Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- PI3K/Akt contributes to increased expression of Toll-like receptor 4 in macrophages exposed to hypoxic stress
- (2012) So Young Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2012) Lei Li et al. LIVER INTERNATIONAL
- High-Mobility Group Box-1 Induces Proinflammatory Cytokines Production of Kupffer Cells through TLRs-Dependent Signaling Pathway after Burn Injury
- (2012) Xu-Lin Chen et al. PLoS One
- Thymosin-β4 (Tβ4) Blunts PDGF-Dependent Phosphorylation and Binding of AKT to Actin in Hepatic Stellate Cells
- (2011) Karina Reyes-Gordillo et al. AMERICAN JOURNAL OF PATHOLOGY
- HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection
- (2011) Ulf Andersson et al. Annual Review of Immunology
- HMGB1, TLR and RAGE: a functional tripod that leads to diabetic inflammation
- (2011) José Augusto Nogueira-Machado et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- The biphasic nature of hypoxia-induced directional migration of activated human hepatic stellate cells
- (2011) Erica Novo et al. JOURNAL OF PATHOLOGY
- Fascin, a novel marker of human hepatic stellate cells, may regulate their proliferation, migration and collagen gene expression through the FAK-PI3K-Akt pathway
- (2011) Naoki Uyama et al. LABORATORY INVESTIGATION
- Up-regulated autophagy by endogenous high mobility group box-1 promotes chemoresistance in leukemia cells
- (2011) Liangchun Yang et al. LEUKEMIA & LYMPHOMA
- High mobility group box-1 induces migration of vascular smooth muscle cells via TLR4-dependent PI3K/Akt pathway activation
- (2011) Jian Yang et al. MOLECULAR BIOLOGY REPORTS
- HMGB1 and RAGE in Inflammation and Cancer
- (2010) Gary P. Sims et al. Annual Review of Immunology
- Ursolic acid ameliorates hepatic fibrosis in the rat by specific induction of apoptosis in hepatic stellate cells
- (2010) Xu Wang et al. JOURNAL OF HEPATOLOGY
- Toll-like Receptor 4 and Hepatic Fibrogenesis
- (2010) Jean-Philippe Pradere et al. SEMINARS IN LIVER DISEASE
- Physiological and pathophysiological outcomes of the interactions of HMGB1 with cell surface receptors
- (2009) Heikki Rauvala et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Sensitization of Human Hepatic Stellate Cells to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Induced Apoptosis by Leflunomide
- (2009) Xiaoming Tang et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Inhibition of phosphatidylinositol 3-kinase signaling in hepatic stellate cells blocks the progression of hepatic fibrosis
- (2009) Gakuhei Son et al. HEPATOLOGY
- Akt-mediated regulation of NFκB and the essentialness of NFκB for the oncogenicity of PI3K and Akt
- (2009) Dong Bai et al. INTERNATIONAL JOURNAL OF CANCER
- Effects of rhubarb on migration of rat hepatic stellate cells
- (2009) Yun-Lian Lin et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Toll-like receptor 4 mediates lipopolysaccharide-induced collagen secretion by phosphoinositide3-kinase-akt pathway in fibroblasts during acute lung injury
- (2009) ZhengYu He et al. JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION
- Raf kinase inhibitor protein inhibits cell proliferation but promotes cell migration in rat hepatic stellate cells
- (2009) Junji Ma et al. LIVER INTERNATIONAL
- Role of the receptor for advanced glycation end products inhepatic fbrosis
- (2009) Christina Lohwasser et al. WORLD JOURNAL OF GASTROENTEROLOGY
- The Role of High Mobility Group Box1 in Pulmonary Fibrosis
- (2008) Naoki Hamada et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- A TLR4/MD2 fusion protein inhibits LPS-induced pro-inflammatory signaling in hepatic stellate cells
- (2008) Bernd Schnabl et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mechanisms of Hepatic Fibrogenesis
- (2008) Scott L. Friedman GASTROENTEROLOGY
- Specific siRNA Targeting the Receptor for Advanced Glycation End Products Inhibits Experimental Hepatic Fibrosis in Rats
- (2008) Jin-Rong Xia et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- High mobility group box 1 protein as a marker of hepatocellular injury in human liver transplantation
- (2008) Minna Ilmakunnas et al. LIVER TRANSPLANTATION
- High mobility group protein B1 enhances DNA repair and chromatin modification after DNA damage
- (2008) S. S. Lange et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- High-Mobility Group Box 1 Protein Activates Hepatic Stellate Cells In Vitro
- (2008) Y.-H. Kao et al. TRANSPLANTATION PROCEEDINGS
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