High Mobility Group Box-1 Promotes the Proliferation and Migration of Hepatic Stellate Cells via TLR4-Dependent Signal Pathways of PI3K/Akt and JNK

High-mobility group box-1 protein induces mucin 8 expression through the activation of the JNK and PI3K/Akt signal pathways in human airway epithelial cells

(2012) Dong Eun Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PI3K/Akt contributes to increased expression of Toll-like receptor 4 in macrophages exposed to hypoxic stress

(2012) So Young Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effect of RhoA on transforming growth factor β1-induced rat hepatic stellate cell migration

(2012) Lei Li et al.   LIVER INTERNATIONAL

High-Mobility Group Box-1 Induces Proinflammatory Cytokines Production of Kupffer Cells through TLRs-Dependent Signaling Pathway after Burn Injury

(2012) Xu-Lin Chen et al.   PLoS One

Thymosin-β4 (Tβ4) Blunts PDGF-Dependent Phosphorylation and Binding of AKT to Actin in Hepatic Stellate Cells

(2011) Karina Reyes-Gordillo et al.   AMERICAN JOURNAL OF PATHOLOGY

HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection

(2011) Ulf Andersson et al.   Annual Review of Immunology

HMGB1, TLR and RAGE: a functional tripod that leads to diabetic inflammation

(2011) José Augusto Nogueira-Machado et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The biphasic nature of hypoxia-induced directional migration of activated human hepatic stellate cells

(2011) Erica Novo et al.   JOURNAL OF PATHOLOGY

Fascin, a novel marker of human hepatic stellate cells, may regulate their proliferation, migration and collagen gene expression through the FAK-PI3K-Akt pathway

(2011) Naoki Uyama et al.   LABORATORY INVESTIGATION

Up-regulated autophagy by endogenous high mobility group box-1 promotes chemoresistance in leukemia cells

(2011) Liangchun Yang et al.   LEUKEMIA & LYMPHOMA

High mobility group box-1 induces migration of vascular smooth muscle cells via TLR4-dependent PI3K/Akt pathway activation

(2011) Jian Yang et al.   MOLECULAR BIOLOGY REPORTS

HMGB1 and RAGE in Inflammation and Cancer

(2010) Gary P. Sims et al.   Annual Review of Immunology

Ursolic acid ameliorates hepatic fibrosis in the rat by specific induction of apoptosis in hepatic stellate cells

(2010) Xu Wang et al.   JOURNAL OF HEPATOLOGY

Toll-like Receptor 4 and Hepatic Fibrogenesis

(2010) Jean-Philippe Pradere et al.   SEMINARS IN LIVER DISEASE

Physiological and pathophysiological outcomes of the interactions of HMGB1 with cell surface receptors

(2009) Heikki Rauvala et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Sensitization of Human Hepatic Stellate Cells to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Induced Apoptosis by Leflunomide

(2009) Xiaoming Tang et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Inhibition of phosphatidylinositol 3-kinase signaling in hepatic stellate cells blocks the progression of hepatic fibrosis

(2009) Gakuhei Son et al.   HEPATOLOGY

Akt-mediated regulation of NFκB and the essentialness of NFκB for the oncogenicity of PI3K and Akt

(2009) Dong Bai et al.   INTERNATIONAL JOURNAL OF CANCER

Effects of rhubarb on migration of rat hepatic stellate cells

(2009) Yun-Lian Lin et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Toll-like receptor 4 mediates lipopolysaccharide-induced collagen secretion by phosphoinositide3-kinase-akt pathway in fibroblasts during acute lung injury

(2009) ZhengYu He et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Raf kinase inhibitor protein inhibits cell proliferation but promotes cell migration in rat hepatic stellate cells

(2009) Junji Ma et al.   LIVER INTERNATIONAL

Role of the receptor for advanced glycation end products inhepatic fbrosis

(2009) Christina Lohwasser et al.   WORLD JOURNAL OF GASTROENTEROLOGY

The Role of High Mobility Group Box1 in Pulmonary Fibrosis

(2008) Naoki Hamada et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

A TLR4/MD2 fusion protein inhibits LPS-induced pro-inflammatory signaling in hepatic stellate cells

(2008) Bernd Schnabl et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

Specific siRNA Targeting the Receptor for Advanced Glycation End Products Inhibits Experimental Hepatic Fibrosis in Rats

(2008) Jin-Rong Xia et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

High mobility group box 1 protein as a marker of hepatocellular injury in human liver transplantation

(2008) Minna Ilmakunnas et al.   LIVER TRANSPLANTATION

High mobility group protein B1 enhances DNA repair and chromatin modification after DNA damage

(2008) S. S. Lange et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-Mobility Group Box 1 Protein Activates Hepatic Stellate Cells In Vitro

(2008) Y.-H. Kao et al.   TRANSPLANTATION PROCEEDINGS