siPools: highly complex but accurately defined siRNA pools eliminate off-target effects

Specific inhibition of diverse pathogens in human cells by synthetic microRNA-like oligonucleotides inferred from RNAi screens

(2014) A. Franceschini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNAi Factors Are Present and Active in Human Cell Nuclei

(2014) Keith T. Gagnon et al.   Cell Reports

The non-coding skin: Exploring the roles of long non-coding RNAs in epidermal homeostasis and disease

(2013) Sonja Hombach et al.   BIOESSAYS

Argonaute proteins: functional insights and emerging roles

(2013) Gunter Meister   NATURE REVIEWS GENETICS

Genome Regulation by Long Noncoding RNAs

(2012) John L. Rinn et al.   Annual Review of Biochemistry

A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens

(2012) Frederic D Sigoillot et al.   NATURE METHODS

HTSanalyzeR: an R/Bioconductor package for integrated network analysis of high-throughput screens

(2011) X. Wang et al.   BIOINFORMATICS

Chemical Modification of siRNA Bases To Probe and Enhance RNA Interference

(2011) Hayden Peacock et al.   JOURNAL OF ORGANIC CHEMISTRY

Gene silencing by microRNAs: contributions of translational repression and mRNA decay

(2011) Eric Huntzinger et al.   NATURE REVIEWS GENETICS

Improved siRNA/shRNA Functionality by Mismatched Duplex

(2011) Haoquan Wu et al.   PLoS One

Thermodynamic stability of small hairpin RNAs highly influences the loading process of different mammalian Argonautes

(2011) S. Gu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased siRNA duplex stability correlates with reduced off-target and elevated on-target effects

(2011) S. Petri et al.   RNA

Dicer is dispensable for asymmetric RISC loading in mammals

(2011) J. G. Betancur et al.   RNA

Vigilance and Validation: Keys to Success in RNAi Screening

(2010) Frederic D. Sigoillot et al.   ACS Chemical Biology

Genomic Screening with RNAi: Results and Challenges

(2010) Stephanie Mohr et al.   Annual Review of Biochemistry

A framework for oligonucleotide microarray preprocessing

(2010) Benilton S. Carvalho et al.   BIOINFORMATICS

Argonaute proteins at a glance

(2010) C. Ender et al.   JOURNAL OF CELL SCIENCE

HSP90 Protein Stabilizes Unloaded Argonaute Complexes and Microscopic P-bodies in Human Cells

(2010) Michael Johnston et al.   MOLECULAR BIOLOGY OF THE CELL

Utilization of unlocked nucleic acid (UNA) to enhance siRNA performance in vitro and in vivo

(2010) Maria B. Laursen et al.   Molecular BioSystems

Hsc70/Hsp90 Chaperone Machinery Mediates ATP-Dependent RISC Loading of Small RNA Duplexes

(2010) Shintaro Iwasaki et al.   MOLECULAR CELL

The widespread regulation of microRNA biogenesis, function and decay

(2010) Jacek Krol et al.   NATURE REVIEWS GENETICS

A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects

(2010) Jesper B. Bramsen et al.   NUCLEIC ACIDS RESEARCH

Importin 8 Is a Gene Silencing Factor that Targets Argonaute Proteins to Distinct mRNAs

(2009) Lasse Weinmann et al.   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

On the road to reading the RNA-interference code

(2009) Haruhiko Siomi et al.   NATURE

A three-dimensional view of the molecular machinery of RNA interference

(2009) Martin Jinek et al.   NATURE

Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application

(2009) Aimee L. Jackson et al.   NATURE REVIEWS DRUG DISCOVERY

E. coli RNase III(E38A) generates discrete-sized products from long dsRNA

(2009) J. Xiao et al.   RNA

Importance of Translation and Nonnucleolytic Ago Proteins for On-Target RNA Interference

(2008) Ligang Wu et al.   CURRENT BIOLOGY

Improved northern blot method for enhanced detection of small RNA

(2008) Gurman S Pall et al.   Nature Protocols

Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect

(2008) Kumiko Ui-Tei et al.   NUCLEIC ACIDS RESEARCH

A multifunctional human Argonaute2-specific monoclonal antibody

(2008) S. Rudel et al.   RNA

Argonaute proteins: key players in RNA silencing

(2007) Gyorgy Hutvagner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY