Guiding principles in the design of ligand-targeted nanomedicines

Toll-like receptor 2: therapeutic target for gastric carcinogenesis

(2015) William McCormack et al.   Oncotarget

Surface Modification for Improving the Stability of Nanoparticles in Liquid Media

(2014) Motoyuki Iijima et al.   KONA Powder and Particle Journal

Avidity Modulation of Folate-Targeted Multivalent Dendrimers for Evaluating Biophysical Models of Cancer Targeting Nanoparticles

(2013) Justin E. Silpe et al.   ACS Chemical Biology

Design Principles for Clinical Efficacy of Cancer Nanomedicine: A Look into the Basics

(2013) Shiladitya Sengupta et al.   ACS Nano

Enhanced Cellular Uptake of Peptide-Targeted Nanoparticles through Increased Peptide Hydrophilicity and Optimized Ethylene Glycol Peptide-Linker Length

(2013) Jared F. Stefanick et al.   ACS Nano

Effect of Folate-Targeted Nanoparticle Size on Their Rates of Penetration into Solid Tumors

(2013) Erina Vlashi et al.   ACS Nano

A Systematic Analysis of Peptide Linker Length and Liposomal Polyethylene Glycol Coating on Cellular Uptake of Peptide-Targeted Liposomes

(2013) Jared F. Stefanick et al.   ACS Nano

Reduction of Nanoparticle Avidity Enhances the Selectivity of Vascular Targeting and PET Detection of Pulmonary Inflammation

(2013) Blaine J. Zern et al.   ACS Nano

Ligand-targeted particulate nanomedicines undergoing clinical evaluation: Current status

(2013) Roy van der Meel et al.   ADVANCED DRUG DELIVERY REVIEWS

The Polyethyleneglycol Dilemma: Advantage and Disadvantage of PEGylation of Liposomes for Systemic Genes and Nucleic Acids Delivery to Tumors

(2013) Hiroto Hatakeyama et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

IR-780 dye loaded tumor targeting theranostic nanoparticles for NIR imaging and photothermal therapy

(2013) Caixia Yue et al.   BIOMATERIALS

A comparative study of chitosan shielding effect on nano-carriers hydrophilicity and biodistribution

(2013) Rania A.H. Ishak et al.   CARBOHYDRATE POLYMERS

Dextran based sensitive theranostic nanoparticles for near-infrared imaging and photothermal therapy in vitro

(2013) Peng Liu et al.   CHEMICAL COMMUNICATIONS

Multivalent glycocalixarenes for recognition of biological macromolecules: glycocalyx mimics capable of multitasking

(2013) Francesco Sansone et al.   CHEMICAL SOCIETY REVIEWS

Glyconanoparticles as multifunctional and multimodal carbohydrate systems

(2013) Marco Marradi et al.   CHEMICAL SOCIETY REVIEWS

Peptide-based Radiopharmaceuticals for Targeted Tumor Therapy

(2013) C. Dong et al.   CURRENT MEDICINAL CHEMISTRY

Delivery of therapeutic nucleic acids via transferrin and transferrin receptors: lipoplexes and other carriers

(2013) Conchita Tros de Ilarduya et al.   Expert Opinion on Drug Delivery

Influence of ligand presentation density on the molecular recognition of mannose-functionalised glyconanoparticles by bacterial lectin BC2L-A

(2013) Michael Reynolds et al.   GLYCOCONJUGATE JOURNAL

Targeting acute myeloid leukemia with a proapoptotic peptide conjugated to a toll-like receptor 2-mediated cell-penetrating peptide

(2013) Ke Li et al.   INTERNATIONAL JOURNAL OF CANCER

Intercellular adhesion molecule-1 (ICAM-1) expression correlates with oral cancer progression and induces macrophage/cancer cell adhesion

(2013) Yu Usami et al.   INTERNATIONAL JOURNAL OF CANCER

Encapsulation of paclitaxel into lauric acid-O-carboxymethyl chitosan-transferrin micelles for hydrophobic drug delivery and site-specific targeted delivery

(2013) Joung-Pyo Nam et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Effect of octreotide surface density on receptor-mediated endocytosis in vitro and anticancer efficacy of modified nanocarrier in vivo after optimization

(2013) Zhigui Su et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Endosomal escape kinetics of mesoporous silica-based system for efficient siRNA delivery

(2013) Mingqi Wang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Imaging Primary Mouse Sarcomas After Radiation Therapy Using Cathepsin-Activatable Fluorescent Imaging Agents

(2013) Kyle C. Cuneo et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

The effect of dual ligand-targeted micelles on the delivery and efficacy of poorly soluble drug for cancer therapy

(2013) Rupa R. Sawant et al.   JOURNAL OF DRUG TARGETING

Discovery of diverse and functional antibodies from large human repertoire antibody libraries

(2013) Lauren J. Schwimmer et al.   JOURNAL OF IMMUNOLOGICAL METHODS

A Phase I Study of Folate Immune Therapy (EC90 Vaccine Administered With GPI-0100 Adjuvant Followed by EC17) in Patients With Renal Cell Carcinoma

(2013) Robert J. Amato et al.   JOURNAL OF IMMUNOTHERAPY

Development and in Vivo Quantitative Magnetic Resonance Imaging of Polymer Micelles Targeted to the Melanocortin 1 Receptor

(2013) Natalie M. Barkey et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and In Vitro and In Vivo Evaluation of Hypoxia-Enhanced 111In-Bombesin Conjugates for Prostate Cancer Imaging

(2013) Z. Zhou et al.   JOURNAL OF NUCLEAR MEDICINE

New views on cellular uptake and trafficking of manufactured nanoparticles

(2013) L. Treuel et al.   Journal of the Royal Society Interface

Transferrin-Conjugated Pluronic Niosomes as a New Drug Delivery System for Anticancer Therapy

(2013) Lorena Tavano et al.   LANGMUIR

Effect of the Spacer Structure on the Stability of Gold Nanoparticles Functionalized with Monodentate Thiolated Poly(ethylene glycol) Ligands

(2013) Florian Schulz et al.   LANGMUIR

Influence of Spacer Length on the Cellular Uptake of Polymeric Nanoparticles

(2013) Frank Thielbeer et al.   MACROMOLECULAR BIOSCIENCE

Deep sequencing of phage display libraries to support antibody discovery

(2013) Ulla Ravn et al.   METHODS

Impact of Tumor Vascularity on Responsiveness to Antiangiogenesis in a Prostate Cancer Stem Cell-Derived Tumor Model

(2013) K. Zhang et al.   MOLECULAR CANCER THERAPEUTICS

In Vivo and in Silico Pharmacokinetics and Biodistribution of a Melanocortin Receptor 1 Targeted Agent in Preclinical Models of Melanoma

(2013) Narges K. Tafreshi et al.   MOLECULAR PHARMACEUTICS

Effective Delivery of siRNA into Cancer Cells and Tumors Using Well-Defined Biodegradable Cationic Star Polymers

(2013) Cyrille Boyer et al.   MOLECULAR PHARMACEUTICS

Use of Folate-Conjugated Imaging Agents To Target Alternatively Activated Macrophages in a Murine Model of Asthma

(2013) Jiayin Shen et al.   MOLECULAR PHARMACEUTICS

Phase I Study of a Systemically Delivered p53 Nanoparticle in Advanced Solid Tumors

(2013) Neil Senzer et al.   MOLECULAR THERAPY

Multifunctional Hierarchically Assembled Nanostructures as Complex Stage-Wise Dual-Delivery Systems for Coincidental Yet Differential Trafficking of siRNA and Paclitaxel

(2013) Mahmoud Elsabahy et al.   NANO LETTERS

Biotargeted nanomedicines for cancer: six tenets before you begin

(2013) Michael S Goldberg et al.   Nanomedicine

Heterogeneity in nanoparticles influences biodistribution and targeting

(2013) Isaac M Adjei et al.   Nanomedicine

Family of pH (low) insertion peptides for tumor targeting

(2013) D. Weerakkody et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Surface modification of inorganic nanoparticles for development of organic–inorganic nanocomposites—A review

(2013) Sarita Kango et al.   PROGRESS IN POLYMER SCIENCE

Targeting cancer cell-specific RNA interference by siRNA delivery using a complex carrier of affibody-displaying bio-nanocapsules and liposomes

(2013) Yuya Nishimura et al.   JOURNAL OF NANOBIOTECHNOLOGY

Liposomal drug delivery systems: From concept to clinical applications

(2012) Theresa M. Allen et al.   ADVANCED DRUG DELIVERY REVIEWS

The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

(2012) Alexandre Albanese et al.   Annual Review of Biomedical Engineering

NGR-based Strategies for Targeting Delivery of Chemotherapeutics to Tumor Vasculature

(2012) Mingming Zou et al.   Anti-Cancer Agents in Medicinal Chemistry

Synthesis and Characterization of a Melanoma-Targeted Fluorescence Imaging Probe by Conjugation of a Melanocortin 1 Receptor (MC1R) Specific Ligand

(2012) Narges K. Tafreshi et al.   BIOCONJUGATE CHEMISTRY

Endosomal escape and siRNA delivery with cationic shell crosslinked knedel-like nanoparticles with tunable buffering capacities

(2012) Ritu Shrestha et al.   BIOMATERIALS

Triazoyl–phenyl linker system enhancing the aqueous solubility of a molecular probe and its efficiency in affinity labeling of a target protein for jasmonate glucoside

(2012) Satoru Tamura et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Targeted nanoparticle delivery overcomes off-target immunostimulatory effects of oligonucleotides and improves therapeutic efficacy in chronic lymphocytic leukemia

(2012) B. Yu et al.   BLOOD

Bioconjugatable Azo-Based Dark-Quencher Dyes: Synthesis and Application to Protease-Activatable Far-Red Fluorescent Probes

(2012) Arnaud Chevalier et al.   CHEMISTRY-A EUROPEAN JOURNAL

Activatable Fluorescent Probes: A New Concept in Optical Molecular Imaging

(2012) E. Lacivita et al.   CURRENT MEDICINAL CHEMISTRY

Organic nanocarriers for cancer drug delivery

(2012) Víctor López-Dávila et al.   CURRENT OPINION IN PHARMACOLOGY

Degradation of BMS-753493, a novel epothilone folate conjugate anticancer agent

(2012) Madhushree Gokhale et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Tailoring the biodegradability of porous silicon nanoparticles

(2012) Nick K. Hon et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Phase I Study of Folate Conjugate EC145 (Vintafolide) in Patients With Refractory Solid Tumors

(2012) Patricia M. LoRusso et al.   JOURNAL OF CLINICAL ONCOLOGY

Immobilization of fluorescein isothiocyanate on magnetic polymeric nanoparticle using chitosan as spacer

(2012) Chariya Kaewsaneha et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Doxil® — The first FDA-approved nano-drug: Lessons learned

(2012) Yechezkel (Chezy) Barenholz   JOURNAL OF CONTROLLED RELEASE

Preparation and Characterization of Folate Targeting Magnetic Nanomedicine Loaded with Cisplatin

(2012) Minqiang Xie et al.   Journal of Nanomaterials

Multicolored pH-Tunable and Activatable Fluorescence Nanoplatform Responsive to Physiologic pH Stimuli

(2012) Kejin Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Abstract C36: MBP-426, a novel liposome-encapsulated oxaliplatin, in combination with 5-FU/leucovorin (LV): Phase I results of a Phase I/II study in gastro-esophageal adenocarcinoma, with pharmacokinetics

(2012) N. N. Senzer et al.   MOLECULAR CANCER THERAPEUTICS

Plasma, tumor and tissue pharmacokinetics of Docetaxel delivered via nanoparticles of different sizes and shapes in mice bearing SKOV-3 human ovarian carcinoma xenograft

(2012) Kevin S. Chu et al.   Nanomedicine-Nanotechnology Biology and Medicine

Effect of ligand density, receptor density, and nanoparticle size on cell targeting

(2012) Drew R. Elias et al.   Nanomedicine-Nanotechnology Biology and Medicine

Factors affecting T cell responses induced by fully synthetic glyco-gold-nanoparticles

(2012) Silvia Fallarini et al.   Nanoscale

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

(2012) Hyukjin Lee et al.   Nature Nanotechnology

Evolution of Bombesin Conjugates for Targeted PET Imaging of Tumors

(2012) Hanwen Zhang et al.   PLoS One

pHLIP peptide targets nanogold particles to tumors

(2012) L. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heterobivalent ligands target cell-surface receptor combinations in vivo

(2012) L. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preclinical Development and Clinical Translation of a PSMA-Targeted Docetaxel Nanoparticle with a Differentiated Pharmacological Profile

(2012) J. Hrkach et al.   Science Translational Medicine

Insights into the endosomal escape mechanism via investigation of dendrimer–membrane interactions

(2012) Wen-de Tian et al.   Soft Matter

Scaffold Diversification Enhances Effectiveness of a Superlibrary of Hyperthermophilic Proteins

(2012) Mahmud Hussain et al.   ACS Synthetic Biology

Self-Assembled Targeted Nanoparticles: Evolution of Technologies and Bench to Bedside Translation

(2011) Jinjun Shi et al.   ACCOUNTS OF CHEMICAL RESEARCH

Synthesis and Evaluation of Folate-Based Chlorambucil Delivery Systems for Tumor-Targeted Chemotherapy

(2011) Annalisa Guaragna et al.   BIOCONJUGATE CHEMISTRY

Intracellular dynamics of cationic and anionic polystyrene nanoparticles without direct interaction with mitotic spindle and chromosomes

(2011) Yuexian Liu et al.   BIOMATERIALS

Enhancement of cell recognition in vitro by dual-ligand cancer targeting gold nanoparticles

(2011) Xi Li et al.   BIOMATERIALS

The high performance of 3XFLAG for target purification of a bioactive metabolite: A tag combined with a highly effective linker structure

(2011) Minoru Ueda et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Multifunctional dendritic polymers in nanomedicine: opportunities and challenges

(2011) Jayant Khandare et al.   CHEMICAL SOCIETY REVIEWS

Targeted drug delivery to tumors: Myths, reality and possibility

(2011) You Han Bae et al.   JOURNAL OF CONTROLLED RELEASE

Recent advances in ligand targeted therapy

(2011) Giuseppe Trapani et al.   JOURNAL OF DRUG TARGETING

Development of Melanoma-Targeted Polymer Micelles by Conjugation of a Melanocortin 1 Receptor (MC1R) Specific Ligand

(2011) Natalie M. Barkey et al.   JOURNAL OF MEDICINAL CHEMISTRY

Safety, Pharmacokinetics, and Activity of GRN1005, a Novel Conjugate of Angiopep-2, a Peptide Facilitating Brain Penetration, and Paclitaxel, in Patients with Advanced Solid Tumors

(2011) R. Kurzrock et al.   MOLECULAR CANCER THERAPEUTICS

Endocytosis and intracellular transport of nanoparticles: Present knowledge and need for future studies

(2011) Tore-Geir Iversen et al.   Nano Today

Targeted drug delivery to tumor vasculature by a carbohydrate mimetic peptide

(2011) S. Hatakeyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Designing super selectivity in multivalent nano-particle binding

(2011) F. J. Martinez-Veracoechea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multistage nanoparticle delivery system for deep penetration into tumor tissue

(2011) C. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Delivery of Molecular and Nanoscale Medicine to Tumors: Transport Barriers and Strategies

(2011) Vikash P. Chauhan et al.   Annual Review of Chemical and Biomolecular Engineering

Target-Cancer-Cell-Specific Activatable Fluorescence Imaging Probes: Rational Design and in Vivo Applications

(2010) Hisataka Kobayashi et al.   ACCOUNTS OF CHEMICAL RESEARCH

Morphing Low-Affinity Ligands into High-Avidity Nanoparticles by Thermally Triggered Self-Assembly of a Genetically Encoded Polymer

(2010) Andrew J. Simnick et al.   ACS Nano

Enzyme-Responsive Intracellular Controlled Release Using Nanometric Silica Mesoporous Supports Capped with “Saccharides”

(2010) Andrea Bernardos et al.   ACS Nano

Glyconanomaterials: Synthesis, Characterization, and Ligand Presentation

(2010) Xin Wang et al.   ADVANCED MATERIALS

Radiolabeled CCK/gastrin peptides for imaging and therapy of CCK2 receptor-expressing tumors

(2010) Susan Roosenburg et al.   AMINO ACIDS

Antibody–drug conjugates: targeted drug delivery for cancer

(2010) Stephen C Alley et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Factors that Control the Circulation Time of Nanoparticles in Blood: Challenges, Solutions and Future Prospects

(2010) Jin-Wook Yoo et al.   CURRENT PHARMACEUTICAL DESIGN

Activatable Molecular Probes for Cancer Imaging

(2010) Seulki Lee et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery

(2010) Fabienne Danhier et al.   JOURNAL OF CONTROLLED RELEASE

Endocytosis of nanomedicines

(2010) Gaurav Sahay et al.   JOURNAL OF CONTROLLED RELEASE

Assessment of Chemoselective Neoglycosylation Methods Using Chlorambucil as a Model

(2010) Randal D. Goff et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Biological Analysis of Prostate-Specific Membrane Antigen-Targeted Anticancer Prodrugs

(2010) Sumith A. Kularatne et al.   JOURNAL OF MEDICINAL CHEMISTRY

Folate-Targeted Therapies for Cancer

(2010) Wei Xia et al.   JOURNAL OF MEDICINAL CHEMISTRY

Reducing Undesirable Hepatic Clearance of a Tumor-Targeted Vinca Alkaloid via Novel Saccharopeptidic Modifications

(2010) C. P. Leamon et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Hyperbranched Polyglycidol Assisted Green Synthetic Protocols for the Preparation of Multifunctional Metal Nanoparticles

(2010) Haiqing Li et al.   LANGMUIR

High sensitivity detection of cancer in vivo using a dual-controlled activation fluorescent imaging probe based on H-dimer formation and pH activation

(2010) Mikako Ogawa et al.   Molecular BioSystems

The Effects of Particle Size and Molecular Targeting on the Intratumoral and Subcellular Distribution of Polymeric Nanoparticles

(2010) Helen Lee et al.   MOLECULAR PHARMACEUTICS

Delivering nanomedicine to solid tumors

(2010) Rakesh K. Jain et al.   Nature Reviews Clinical Oncology

Strategies in the design of nanoparticles for therapeutic applications

(2010) Robby A. Petros et al.   NATURE REVIEWS DRUG DISCOVERY

Targeting nanoparticles to cancer

(2010) M. Wang et al.   PHARMACOLOGICAL RESEARCH

Computational model for nanocarrier binding to endothelium validated using in vivo, in vitro, and atomic force microscopy experiments

(2010) J. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vivo optical imaging in arthritis--an enlightening future?

(2010) L. L. Gompels et al.   RHEUMATOLOGY

Receptor Mediated Tumor Targeting: An Emerging Approach for Cancer Therapy

(2010) Chandana Mohanty et al.   Current Drug Delivery

H-Type Dimer Formation of Fluorophores: A Mechanism for Activatable,in VivoOptical Molecular Imaging

(2009) Mikako Ogawa et al.   ACS Chemical Biology

Designer Biomaterials for Nanomedicine

(2009) Nishit Doshi et al.   ADVANCED FUNCTIONAL MATERIALS

Ligand-Targeted Delivery of Small Interfering RNAs to Malignant Cells and Tissues

(2009) Mini Thomas et al.   Annals of the New York Academy of Sciences

Arabinogalactan−Folic Acid−Drug Conjugate for Targeted Delivery and Target-Activated Release of Anticancer Drugs to Folate Receptor-Overexpressing Cells

(2009) Roy I. Pinhassi et al.   BIOMACROMOLECULES

Long-circulating polymeric nanoparticles bearing a combinatorial coating of PEG and water-soluble chitosan

(2009) Yan Sheng et al.   BIOMATERIALS

Improved therapeutic activity of folate-targeted liposomal doxorubicin in folate receptor-expressing tumor models

(2009) Alberto Gabizon et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

In vivo Molecular Imaging of Cancer with a Quenching Near-Infrared Fluorescent Probe Using Conjugates of Monoclonal Antibodies and Indocyanine Green

(2009) Mikako Ogawa et al.   CANCER RESEARCH

Computationally Guided Photothermal Tumor Therapy Using Long-Circulating Gold Nanorod Antennas

(2009) G. von Maltzahn et al.   CANCER RESEARCH

Multivalent ligand presentation as a central concept to study intricate carbohydrate–protein interactions

(2009) Narayanaswamy Jayaraman   CHEMICAL SOCIETY REVIEWS

Folate-targeted therapeutic and imaging agents for cancer

(2009) Philip Stewart Low et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

A randomised Phase III trial of glufosfamide compared with best supportive care in metastatic pancreatic adenocarcinoma previously treated with gemcitabine

(2009) Tudor E. Ciuleanu et al.   EUROPEAN JOURNAL OF CANCER

Ligand-based targeted therapy for cancer tissue

(2009) Manasi Das et al.   Expert Opinion on Drug Delivery

Dual-targeting daunorubicin liposomes improve the therapeutic efficacy of brain glioma in animals

(2009) Xue Ying et al.   JOURNAL OF CONTROLLED RELEASE

Role of nanocarrier systems in cancer nanotherapy

(2009) M. R. Mozafari et al.   JOURNAL OF LIPOSOME RESEARCH

Biodegradable PLGA based nanoparticles for sustained regional lymphatic drug delivery

(2009) Deepa A. Rao et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

A Near-Infrared Neutral pH Fluorescent Probe for Monitoring Minor pH Changes: Imaging in Living HepG2 and HL-7702 Cells

(2009) Bo Tang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In vivo target-specific activatable near-infrared optical labeling of humanized monoclonal antibodies

(2009) M. Ogawa et al.   MOLECULAR CANCER THERAPEUTICS

Prostate-Specific Membrane Antigen Targeted Imaging and Therapy of Prostate Cancer Using a PSMA Inhibitor as a Homing Ligand

(2009) Sumith A. Kularatne et al.   MOLECULAR PHARMACEUTICS

In Vivo Structural Activity and Optimization Studies of Folate−Tubulysin Conjugates

(2009) Joseph A. Reddy et al.   MOLECULAR PHARMACEUTICS

Fluorophore−Quencher Based Activatable Targeted Optical Probes for Detectingin VivoCancer Metastases

(2009) Mikako Ogawa et al.   MOLECULAR PHARMACEUTICS

The First Targeted Delivery of siRNA in Humans via a Self-Assembling, Cyclodextrin Polymer-Based Nanoparticle: From Concept to Clinic

(2009) Mark E. Davis   MOLECULAR PHARMACEUTICS

Mediating Tumor Targeting Efficiency of Nanoparticles Through Design

(2009) Steven D. Perrault et al.   NANO LETTERS

Synergistic Targeting of αvβ3Integrin and Galectin-1 with Heteromultivalent Paramagnetic Liposomes for Combined MR Imaging and Treatment of Angiogenesis

(2009) Ewelina Kluza et al.   NANO LETTERS

Design considerations for tumour-targeted nanoparticles

(2009) Hak Soo Choi et al.   Nature Nanotechnology

Tunable immunonanoparticle binding to cancer cells: thermodynamic analysis of targeted drug delivery vehicles

(2009) Karyn Ho et al.   Soft Matter

Frontiers in Nanoparticle Research: Toward Greater Complexity of Structure and Function of Nanomaterials

(2008) Nicholas A. Kotov et al.   ADVANCED MATERIALS

Magnetic Iron Oxide Nanoworms for Tumor Targeting and Imaging

(2008) Ji-Ho Park et al.   ADVANCED MATERIALS

Size-Dependent Endocytosis of Nanoparticles

(2008) Sulin Zhang et al.   ADVANCED MATERIALS

Structural basis for mannose recognition by a lectin from opportunistic bacteriaBurkholderia cenocepacia

(2008) Emilie Lameignere et al.   BIOCHEMICAL JOURNAL

Tumour-targeted nanomedicines: principles and practice

(2008) T Lammers et al.   BRITISH JOURNAL OF CANCER

Antibody-Drug Conjugates for Cancer Therapy

(2008) Paul J. Carter et al.   CANCER JOURNAL

Activatable imaging probes with amplified fluorescent signals

(2008) Seulki Lee et al.   CHEMICAL COMMUNICATIONS

Physical approaches to biomaterial design

(2008) Samir Mitragotri et al.   NATURE MATERIALS

The effect of particle design on cellular internalization pathways

(2008) S. E. A. Gratton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Does a targeting ligand influence nanoparticle tumor localization or uptake?

(2008) Kathleen F. Pirollo et al.   TRENDS IN BIOTECHNOLOGY