Curcumin Differs from Tetrahydrocurcumin for Molecular Targets, Signaling Pathways and Cellular Responses

Curcumin, a component of golden spice: From bedside to bench and back

(2014) Sahdeo Prasad et al.   BIOTECHNOLOGY ADVANCES

Differential cellular uptake and metabolism of curcuminoids in monocytes/macrophages: regulatory effects on lipid accumulation

(2014) Kiyotaka Nakagawa et al.   BRITISH JOURNAL OF NUTRITION

Tetrahydrocurcumin induces G2/M cell cycle arrest and apoptosis involving p38 MAPK activation in human breast cancer cells

(2014) Ning Kang et al.   FOOD AND CHEMICAL TOXICOLOGY

Recent Developments in Delivery, Bioavailability, Absorption and Metabolism of Curcumin: the Golden Pigment from Golden Spice

(2014) Sahdeo Prasad et al.   Cancer Research and Treatment

Novel racemic tetrahydrocurcuminoid dihydropyrimidinone analogues as potent acetylcholinesterase inhibitors

(2013) Sarawalee Arunkhamkaew et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Curcumin-loaded solid lipid nanoparticles have prolonged in vitro antitumour activity, cellular uptake and improved in vivo bioavailability

(2013) Jiabei Sun et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Structure-activity relationship analysis of curcumin analogues on anti-influenza virus activity

(2013) Jun-Lin Ou et al.   FEBS Journal

Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells

(2013) Anggakusuma et al.   GUT

Inhibition of Enveloped Viruses Infectivity by Curcumin

(2013) Tzu-Yen Chen et al.   PLoS One

Curcuma longa Extract Associated with White Pepper Lessens High Fat Diet-Induced Inflammation in Subcutaneous Adipose Tissue

(2013) Audrey M. Neyrinck et al.   PLoS One

Inhibition of Ca2+ release-activated Ca2+ channel (CRAC) by curcumin and caffeic acid phenethyl ester (CAPE) via electrophilic addition to a cysteine residue of Orai1

(2012) Dong Hoon Shin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Optimized Turmeric Extract Reduces ?-Amyloid and Phosphorylated Tau Protein Burden in Alzheimer's Transgenic Mice

(2012) R. Douglas Shytle et al.   Current Alzheimer Research

In vitro antioxidant and anti-inflammatory activities of 1-dehydro-[6]-gingerdione, 6-shogaol, 6-dehydroshogaol and hexahydrocurcumin

(2012) Feng Li et al.   FOOD CHEMISTRY

Hexahydrocurcumin enhances inhibitory effect of 5-fluorouracil on HT-29 human colon cancer cells

(2012) Khanitta Srimuangwong   WORLD JOURNAL OF GASTROENTEROLOGY

RETRACTED: Suppression of pro-inflammatory and proliferative pathways by diferuloylmethane (curcumin) and its analogues dibenzoylmethane, dibenzoylpropane, and dibenzylideneacetone: Role of Michael acceptors and Michael donors

(2011) Preetha Anand et al.   BIOCHEMICAL PHARMACOLOGY

Regulatory effects of curcumin on lipid accumulation in monocytes/macrophages

(2011) Jean-Marc Zingg et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Review of Chemical Synthesis of Hormones, Pheromones and Other Bioregulators Chemical Synthesis of Hormones, Pheromones and Other Bioregulators . Edited by K.Mori ( University of Tokyo ). John Wiley & Sons Ltd. , Chichester . 2010 . xiv + 299. 19 × 24.5 cm. $65.00. ISBN 978-0-470-69724-5 (softcover).

(2011) Qiao-Hong Chen   JOURNAL OF NATURAL PRODUCTS

Tetrahydrocurcumin is more effective than curcumin in preventing azoxymethane-induced colon carcinogenesis

(2011) Ching-Shu Lai et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Multitargeting by curcumin as revealed by molecular interaction studies

(2011) Subash C. Gupta et al.   NATURAL PRODUCT REPORTS

EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy

(2011) Joachim Lupberger et al.   NATURE MEDICINE

Antioxidant and vascular protective effects of curcumin and tetrahydrocurcumin in rats with l-NAME-induced hypertension

(2011) Saowanee Nakmareong et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Discovery of the curcumin metabolic pathway involving a unique enzyme in an intestinal microorganism

(2011) A. Hassaninasab et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular docking studies of curcumin analogs with phospholipase A2

(2011) K. V. Dileep et al.   Interdisciplinary Sciences-Computational Life Sciences

Targeting Inflammation-Induced Obesity and Metabolic Diseases by Curcumin and Other Nutraceuticals

(2010) Bharat B. Aggarwal   Annual Review of Nutrition

Curcuminoids activate p38 MAP kinases and promote UVB-dependent signalling in keratinocytes

(2010) Elias E. Ayli et al.   EXPERIMENTAL DERMATOLOGY

A liquid chromatography–tandem mass spectrometric method for quantification of curcuminoids in cell medium and mouse plasma

(2010) U.V.R. Vijaya Saradhi et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Curcumin inhibits influenza virus infection and haemagglutination activity

(2009) Da-Yuan Chen et al.   FOOD CHEMISTRY

Dimethoxycurcumin, a Synthetic Curcumin Analogue, Induces Heme Oxygenase-1 Expression through Nrf2 Activation in RAW264.7 Macrophages

(2009) Sun-Oh Jeong et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Determining the Effects of Lipophilic Drugs on Membrane Structure by Solid-State NMR Spectroscopy: The Case of the Antioxidant Curcumin

(2009) Jeffrey Barry et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Natural derivatives of curcumin attenuate the Wnt/β-catenin pathway through down-regulation of the transcriptional coactivator p300

(2008) Min-Jung Ryu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Curcumin is a potent DNA hypomethylation agent

(2008) Zhongfa Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Effect of tetrahydrocurcumin on insulin receptor status in type 2 diabetic rats: studies on insulin binding to erythrocytes

(2008) Pidaran Murugan et al.   JOURNAL OF BIOSCIENCES

Heme oxygenase-1 mediates the anti-inflammatory effect of Curcumin within LPS-stimulated human monocytes

(2008) Hsien-Yeh Hsu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Curcumin Structure-Function, Bioavailability, and Efficacy in Models of Neuroinflammation and Alzheimer's Disease

(2008) A. N. Begum et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Multi-targeted therapy by curcumin: how spicy is it?

(2008) Ajay Goel et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Dimethoxycurcumin, a synthetic curcumin analogue with higher metabolic stability, inhibits NO production, inducible NO synthase expression and NF-κB activation in RAW264.7 macrophages activated with LPS

(2008) Hyun-Ock Pae et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets

(2008) Bharat B. Aggarwal et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Anti-cancer and anti-angiogenic effects of curcumin and tetrahydrocurcumin on implanted hepatocellular carcinoma in nude mice

(2008) Pornprom Yoysungnoen et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Inhibition of monoamine oxidase-B by the polyphenolic compound, curcumin and its metabolite tetrahydrocurcumin, in a model of Parkinson’s disease induced by MPTP neurodegeneration in mice

(2008) A. Rajeswari et al.   INFLAMMOPHARMACOLOGY

Curcumin attenuates dimethylnitrosamine-induced liver injury in rats through Nrf2-mediated induction of heme oxygenase-1

(2007) E. Olatunde Farombi et al.   FOOD AND CHEMICAL TOXICOLOGY