Multitargeting by curcumin as revealed by molecular interaction studies

Interaction of a Curcumin Analogue Dimethoxycurcumin with DNA

(2011) Amit Kunwar et al.   Chemical Biology & Drug Design

Epigenetic changes induced by curcumin and other natural compounds

(2011) Simone Reuter et al.   Genes and Nutrition

Targeting Sarcoplasmic/Endoplasmic Reticulum Ca2+-ATPase 2 by Curcumin Induces ER Stress-Associated Apoptosis for Treating Human Liposarcoma

(2011) L. Wang et al.   MOLECULAR CANCER THERAPEUTICS

Neuroprotection by Spice-Derived Nutraceuticals: You Are What You Eat!

(2011) Ramaswamy Kannappan et al.   MOLECULAR NEUROBIOLOGY

Relationship between the tautomeric structures of curcumin derivatives and their Aβ-binding activities in the context of therapies for Alzheimer's disease

(2010) Daijiro Yanagisawa et al.   BIOMATERIALS

Binding of curcumin and its long chain derivatives to the activator binding domain of novel protein kinase C

(2010) Anjoy Majhi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Identification of curcumin derivatives as human glyoxalase I inhibitors: A combination of biological evaluation, molecular docking, 3D-QSAR and molecular dynamics simulation studies

(2010) Minggui Yuan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Curcumin derivatives inhibit testicular 17β-hydroxysteroid dehydrogenase 3

(2010) Guo-Xin Hu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Inhibitory Effect of Curcumin on IMP Dehydrogenase, the Target for Anticancer and Antiviral Chemotherapy Agents

(2010) Issei DAIRAKU et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals

(2010) Subash C. Gupta et al.   CANCER AND METASTASIS REVIEWS

Probing the binding site of curcumin in Escherichia coli and Bacillus subtilis FtsZ – A structural insight to unveil antibacterial activity of curcumin

(2010) Simranjeet Kaur et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Interaction of Curcumin with β-Lactoglobulin—Stability, Spectroscopic Analysis, and Molecular Modeling of the Complex

(2010) Athahalli H. Sneharani et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Resveratrol, Genistein, and Curcumin Bind Bovine Serum Albumin†

(2010) P. Bourassa et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Curcumin, the Golden Spice From Indian Saffron, Is a Chemosensitizer and Radiosensitizer for Tumors and Chemoprotector and Radioprotector for Normal Organs

(2010) Ajay Goel et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Binding and stabilization of transthyretin by curcumin

(2009) Raghu Pullakhandam et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Demethoxycurcumin induces Bcl-2 mediated G2/M arrest and apoptosis in human glioma U87 cells

(2009) Pratibha Mehta Luthra et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Potent and selective inhibition of the tumor marker AKR1B10 by bisdemethoxycurcumin: Probing the active site of the enzyme with molecular modeling and site-directed mutagenesis

(2009) Toshiyuki Matsunaga et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies

(2009) Gamze Bora-Tatar et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Insights into the inhibition of xanthine oxidase by curcumin

(2009) Liang Shen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Interactions of curcumin with the PfATP6 model and the implications for its antimalarial mechanism

(2009) Hong-Fang Ji et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Effect of curcumin on the amyloid fibrillogenesis of hen egg-white lysozyme

(2009) Steven S.-S. Wang et al.   BIOPHYSICAL CHEMISTRY

Binding of curcumin with glyoxalase I: Molecular docking, molecular dynamics simulations, and kinetics analysis

(2009) Ming Liu et al.   BIOPHYSICAL CHEMISTRY

Curcumin Binding to DNA and RNA

(2009) Shohreh Nafisi et al.   DNA AND CELL BIOLOGY

Inhibition of aldose reductase by dietary antioxidant curcumin: Mechanism of inhibition, specificity and significance

(2009) P. Muthenna et al.   FEBS LETTERS

Interaction of αS1-Casein with Curcumin and Its Biological Implications

(2009) Athahalli H. Sneharani et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Inhibition Studies of Bovine Xanthine Oxidase by Luteolin, Silibinin, Quercetin, and Curcumin

(2009) James M. Pauff et al.   JOURNAL OF NATURAL PRODUCTS

Photophysics, photochemistry and photobiology of curcumin: Studies from organic solutions, bio-mimetics and living cells

(2009) K. Indira Priyadarsini   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY C-PHOTOCHEMISTRY REVIEWS

Effective Stabilization of Curcumin by Association to Plasma Proteins: Human Serum Albumin and Fibrinogen

(2009) Mandy H. M. Leung et al.   LANGMUIR

Primers on Molecular Pathways — Lipoxygenases: Their Role as an Oncogenic Pathway in Pancreatic Cancer

(2009) A. Comba et al.   PANCREATOLOGY

Fluorocurcumins as Cyclooxygenase-2 Inhibitor: Molecular Docking, Pharmacokinetics and Tissue Distribution in Mice

(2009) Subhash Padhye et al.   PHARMACEUTICAL RESEARCH

An Investigation of the Molecular Interactions of Diacetylcurcumin with Ribonuclease A

(2009) Bijaya Sahoo et al.   PROTEIN AND PEPTIDE LETTERS

Interaction of Curcumin and Diacetylcurcumin with the Lipocalin Member β-Lactoglobulin

(2009) Fakhrossadat Mohammadi et al.   PROTEIN JOURNAL

Curcumin inhibits FtsZ assembly: an attractive mechanism for its antibacterial activity

(2008) Dipti Rai et al.   BIOCHEMICAL JOURNAL

Fluorescence Study of the Curcumin−Casein Micelle Complexation and Its Application as a Drug Nanocarrier to Cancer Cells

(2008) Abhishek Sahu et al.   BIOMACROMOLECULES

Curcumin is a potent DNA hypomethylation agent

(2008) Zhongfa Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Molecular interactions of isoxazolcurcumin with human serum albumin: Spectroscopic and molecular modeling studies

(2008) Bijaya Ketan Sahoo et al.   BIOPOLYMERS

Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins

(2008) Ajaikumar B. Kunnumakkara et al.   CANCER LETTERS

Curcumin Inhibits the Proteasome Activity in Human Colon Cancer Cells In vitro and In vivo

(2008) V. Milacic et al.   CANCER RESEARCH

Olanzapine inhibits glycogen synthase kinase-3β: An investigation by docking simulation and experimental validation

(2008) Mohammad K. Mohammad et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Interaction of curcumin with intravenous immunoglobulin: A fluorescence quenching and Fourier transformation infrared spectroscopy study

(2008) Y LIU et al.   IMMUNOBIOLOGY

Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases

(2008) Bharat B. Aggarwal et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Inhibition of glycogen synthase kinase by curcumin: Investigation by simulated molecular docking and subsequentin vitro/in vivoevaluation

(2008) Yasser Bustanji et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Pharmacophore Modeling, Quantitative Structure–Activity Relationship Analysis, and in Silico Screening Reveal Potent Glycogen Synthase Kinase-3β Inhibitory Activities for Cimetidine, Hydroxychloroquine, and Gemifloxacin

(2008) Mutasem O. Taha et al.   JOURNAL OF MEDICINAL CHEMISTRY

Study of curcumin and genistein interactions with human serum albumin

(2008) Jean-Sébastien Mandeville et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Inhibitory effect of curcuminoids on acetylcholinesterase activity and attenuation of scopolamine-induced amnesia may explain medicinal use of turmeric in Alzheimer's disease

(2008) Touqeer Ahmed et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets

(2008) Bharat B. Aggarwal et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Curcumin as “Curecumin”: From kitchen to clinic

(2007) Ajay Goel et al.   BIOCHEMICAL PHARMACOLOGY

Investigating the binding of curcumin derivatives to bovine serum albumin

(2007) Bijaya Ketan Sahoo et al.   BIOPHYSICAL CHEMISTRY

Studies on the interaction of isoxazolcurcumin with calf thymus DNA

(2007) Rabindranath Bera et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Loading of curcumin into macrophages using lipid-based nanoparticles

(2007) Keitaro Sou et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Micelles of poly(ethylene oxide)‐b‐poly(ε‐caprolactone) as vehicles for the solubilization, stabilization, and controlled delivery of curcumin

(2007) Zengshuan Ma et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Solubilization of hydrophobic drugs by methoxy poly(ethylene glycol)‐block‐polycaprolactone diblock copolymer micelles: Theoretical and experimental data and correlations

(2007) Kevin Letchford et al.   JOURNAL OF PHARMACEUTICAL SCIENCES