Development of a therapeutic monoclonal antibody that targets secreted fatty acid–binding protein aP2 to treat type 2 diabetes
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Title
Development of a therapeutic monoclonal antibody that targets secreted fatty acid–binding protein aP2 to treat type 2 diabetes
Authors
Keywords
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Journal
Science Translational Medicine
Volume 7, Issue 319, Pages 319ra205-319ra205
Publisher
American Association for the Advancement of Science (AAAS)
Online
2015-12-24
DOI
10.1126/scitranslmed.aac6336
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- (2014) J. Saksi et al. Circulation-Cardiovascular Genetics
- Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity
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- (2014) Young-Wook Won et al. NATURE MATERIALS
- FABP4 is secreted from adipocytes by adenyl cyclase-PKA- and guanylyl cyclase-PKG-dependent lipolytic mechanisms
- (2014) Tomohiro Mita et al. Obesity
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- (2013) Hai-yan Cai et al. ACTA PHARMACOLOGICA SINICA
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- (2013) Chi-Lun Huang et al. Cardiovascular Diabetology
- Adipocyte Lipid Chaperone aP2 Is a Secreted Adipokine Regulating Hepatic Glucose Production
- (2013) Haiming Cao et al. Cell Metabolism
- Adipocyte fatty acid-binding protein is released from adipocytes by a non-conventional mechanism
- (2013) S Kralisch et al. INTERNATIONAL JOURNAL OF OBESITY
- Calcium-dependent release of adipocyte fatty acid binding protein from human adipocytes
- (2013) I Schlottmann et al. INTERNATIONAL JOURNAL OF OBESITY
- The rapid generation of recombinant functional monoclonal antibodies from individual, antigen-specific bone marrow-derived plasma cells isolated using a novel fluorescence-based method
- (2013) Alison M Clargo et al. mAbs
- Circulating Levels of Fatty Acid-Binding Protein Family and Metabolic Phenotype in the General Population
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- (2013) Wing Sun Chow et al. Journal of the American Heart Association
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- (2012) Bernhard M. Kaess et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover
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- Pharmacological inhibition of adipocyte fatty acid binding protein alleviates both acute liver injury and non-alcoholic steatohepatitis in mice
- (2012) Ruby L.C. Hoo et al. JOURNAL OF HEPATOLOGY
- Small-molecule inhibitors of FABP4/5 ameliorate dyslipidemia but not insulin resistance in mice with diet-induced obesity
- (2011) Hong Lan et al. JOURNAL OF LIPID RESEARCH
- Serum Fatty Acid-Binding Protein 4 Is a Predictor of Cardiovascular Events in End-Stage Renal Disease
- (2011) Masato Furuhashi et al. PLoS One
- Serum Adipocyte Fatty Acid-Binding Protein Is Associated Independently with Vascular Inflammation: Analysis with18F-Fluorodeoxyglucose Positron Emission Tomography
- (2010) Hye Jin Yoo et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Serum fatty acid binding protein 4, free fatty acids, and metabolic risk markers
- (2009) Sidika E. Karakas et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Identification of a Lipokine, a Lipid Hormone Linking Adipose Tissue to Systemic Metabolism
- (2008) Haiming Cao et al. CELL
- Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets
- (2008) Masato Furuhashi et al. NATURE REVIEWS DRUG DISCOVERY
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