Development of a therapeutic monoclonal antibody that targets secreted fatty acid–binding protein aP2 to treat type 2 diabetes

Serum Levels of Adipocyte Fatty Acid–Binding Protein Are Independently Associated With Left Ventricular Mass and Myocardial Performance Index in Obstructive Sleep Apnea Syndrome

(2016) Mustafa Mücahit Balci et al.   JOURNAL OF INVESTIGATIVE MEDICINE

The mAb against adipocyte fatty acid-binding protein 2E4 attenuates the inflammation in the mouse model of high-fat diet-induced obesity via toll-like receptor 4 pathway

(2015) Xiaoliang Miao et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Metabolic functions of FABPs—mechanisms and therapeutic implications

(2015) Gökhan S. Hotamisligil et al.   Nature Reviews Endocrinology

Circulating adipocyte fatty acid-binding protein induces insulin resistance in micein vivo

(2015) Susan Kralisch et al.   Obesity

Low-Expression Variant of Fatty Acid-Binding Protein 4 Favors Reduced Manifestations of Atherosclerotic Disease and Increased Plaque Stability

(2014) J. Saksi et al.   Circulation-Cardiovascular Genetics

Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity

(2014) Meric Erikci Ertunc et al.   JOURNAL OF LIPID RESEARCH

Oligopeptide complex for targeted non-viral gene delivery to adipocytes

(2014) Young-Wook Won et al.   NATURE MATERIALS

FABP4 is secreted from adipocytes by adenyl cyclase-PKA- and guanylyl cyclase-PKG-dependent lipolytic mechanisms

(2014) Tomohiro Mita et al.   Obesity

Fatty Acid Binding Protein 4 and 5 Play a Crucial Role in Thermogenesis under the Conditions of Fasting and Cold Stress

(2014) Mas Rizky A. A. Syamsunarno et al.   PLoS One

Serum AFBP levels are elevated in patients with nonalcoholic fatty liver disease

(2014) Jun-Bin Suh et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Benzbromarone, an old uricosuric drug, inhibits human fatty acid binding protein 4 in vitro and lowers the blood glucose level in db/db mice

(2013) Hai-yan Cai et al.   ACTA PHARMACOLOGICA SINICA

Association between serum adipocyte fatty-acid binding protein concentrations, left ventricular function and myocardial perfusion abnormalities in patients with coronary artery disease

(2013) Chi-Lun Huang et al.   Cardiovascular Diabetology

Adipocyte Lipid Chaperone aP2 Is a Secreted Adipokine Regulating Hepatic Glucose Production

(2013) Haiming Cao et al.   Cell Metabolism

Adipocyte fatty acid-binding protein is released from adipocytes by a non-conventional mechanism

(2013) S Kralisch et al.   INTERNATIONAL JOURNAL OF OBESITY

Calcium-dependent release of adipocyte fatty acid binding protein from human adipocytes

(2013) I Schlottmann et al.   INTERNATIONAL JOURNAL OF OBESITY

The rapid generation of recombinant functional monoclonal antibodies from individual, antigen-specific bone marrow-derived plasma cells isolated using a novel fluorescence-based method

(2013) Alison M Clargo et al.   mAbs

Circulating Levels of Fatty Acid-Binding Protein Family and Metabolic Phenotype in the General Population

(2013) Shutaro Ishimura et al.   PLoS One

Elevated Circulating Adipocyte‐Fatty Acid Binding Protein Levels Predict Incident Cardiovascular Events in a Community‐Based Cohort: A 12‐Year Prospective Study

(2013) Wing Sun Chow et al.   Journal of the American Heart Association

Circulating Adipocyte Fatty Acid-Binding Protein Levels and Cardiovascular Morbidity and Mortality in Patients With Coronary Heart Disease

(2012) Maximilian von Eynatten et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cardiometabolic Correlates and Heritability of Fetuin-A, Retinol-Binding Protein 4, and Fatty-Acid Binding Protein 4 in the Framingham Heart Study

(2012) Bernhard M. Kaess et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover

(2012) Roger H. Unger et al.   JOURNAL OF CLINICAL INVESTIGATION

Pharmacological inhibition of adipocyte fatty acid binding protein alleviates both acute liver injury and non-alcoholic steatohepatitis in mice

(2012) Ruby L.C. Hoo et al.   JOURNAL OF HEPATOLOGY

Small-molecule inhibitors of FABP4/5 ameliorate dyslipidemia but not insulin resistance in mice with diet-induced obesity

(2011) Hong Lan et al.   JOURNAL OF LIPID RESEARCH

Serum Fatty Acid-Binding Protein 4 Is a Predictor of Cardiovascular Events in End-Stage Renal Disease

(2011) Masato Furuhashi et al.   PLoS One

Serum Adipocyte Fatty Acid-Binding Protein Is Associated Independently with Vascular Inflammation: Analysis with18F-Fluorodeoxyglucose Positron Emission Tomography

(2010) Hye Jin Yoo et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Serum fatty acid binding protein 4, free fatty acids, and metabolic risk markers

(2009) Sidika E. Karakas et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Identification of a Lipokine, a Lipid Hormone Linking Adipose Tissue to Systemic Metabolism

(2008) Haiming Cao et al.   CELL

Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets

(2008) Masato Furuhashi et al.   NATURE REVIEWS DRUG DISCOVERY